2.7.1.50: hydroxyethylthiazole kinase

This is an abbreviated version!
For detailed information about hydroxyethylthiazole kinase, go to the full flat file.

Reaction

Synonyms

4-methyl-5-(beta-hydroxyethyl) thiazole kinase, 4-methyl-5-(beta-hydroxyethyl)thiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase , 4-methyl-5-hydroxyethylthiazole kinase, At3g24030, GRMZM2G094558, hydroxyethylthiazole kinase/thiamine-phosphate pyrophosphorylase, kinase, hydroxyethylthiazole (phosphorylating), More, SaThiM, TH kinase, THI6, thiazole kinase, ThiK, ThiM, THZ kinase

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.1 Phosphotransferases with an alcohol group as acceptor

                2.7.1.50 hydroxyethylthiazole kinase

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Results	in table
14495	AA Sequence
1	CAS Registry Number
5	Cloned(Commentary)
2	Cofactor
5	Crystallization (Commentary)
13	General Information
2	Inhibitors
3	kcat/KM [mM/s]
1	Ki Value [mM]
6	KM Value [mM]
10	Metals/Ions
5	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
57	Organism
7	Pathway
74	PDB ID
2	pH Optimum
1	pH Range
1	Protein Variants
5	Purification (Commentary)
3	Reaction
1	Reaction Type
15	Reference
22	Specific Activity [micromol/min/mg]
1	Storage Stability
37	Substrates and Products (Substrate)
12	Subunits
36	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Stability [°C]
3	Turnover Number [1/s]

KM Value

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KM Value on EC 2.7.1.50 - hydroxyethylthiazole kinase

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KM VALUE [mM]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

8.34

1,3,5-trimethyl-4-(2-hydroxyethyl)pyrazole

Staphylococcus aureus

Q6GEY3

pH 7.5, 37°C

760137

8.31

2-methyl-3-(2-hydroxyethyl)imidazole

Staphylococcus aureus

Q6GEY3

pH 7.5, 37°C

760137

0.044

4-methyl-5-(2-hydroxyethyl)thiazole

Staphylococcus aureus

Q6GEY3

pH 7.5, 37°C

760137

0.0057

5-(2-hydroxyethyl)-4-methylthiazole

Saccharomyces cerevisiae

-

pH 7.5, 37°C

639720

0.79

ATP

Saccharomyces cerevisiae

-

pH 7.5, 37°C

639720

additional information

additional information

Bacillus subtilis

P39593

modeling of stationary points along the reaction pathway, determination of relative energies of the transition state and product

693705

-