2.7.1.52: fucokinase
This is an abbreviated version!
For detailed information about fucokinase, go to the full flat file.
Word Map on EC 2.7.1.52
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2.7.1.52
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salvage
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fucosyltransferase
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3hfucose
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reutilization
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gdp-alpha-d-mannose
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gdp-beta-l-fucose
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synthesis
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analysis
- 2.7.1.52
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salvage
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fucosyltransferase
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3hfucose
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reutilization
- gdp-alpha-d-mannose
- gdp-beta-l-fucose
- synthesis
- analysis
Reaction
Synonyms
ATP:6-deoxy-beta-L-galactose 1-phosphotransferase, ATP:6-deoxy-L-galactose 1-phospho transferase, Fkgp, FKP, fucokinase, fucokinase/L-fucose-1-P-guanylyltransferase, fucokinase:GDP-fucose pyrophosphorylase, fucose kinase, Fuk, kinase, fuco- (phosphorylating), L-fucokinase, L-fucokinase/guanosine 5'-diphosphate-L-fucose pyrophosphorylase, L-fucokinase/guanosine-5'-diphosphate-Fuc pyrophosphorylase, L-fucokinase:GDP-fucose pyrophosphorylase, L-fucose kinase, L-fucose kinase/GDP-L-fucose pyrophosphorylase, More
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2.7.1.52 fucokinaseAdvanced search results
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results (Natural Substrates Products
Natural Substrates Products on EC 2.7.1.52 - fucokinase
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
ATP + 6-deoxy-L-galactose
ADP + 6-deoxy-L-galactose 1-phosphate
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i.e. L-fucose, serves to utilize free L-fucose for glycoprotein synthesis
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?
ATP + 6-deoxy-L-galactose
ADP + 6-deoxy-L-galactose 1-phosphate
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enzyme is part of a salvage pathway for reutilization of L-fucose
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?
ATP + 6-deoxy-L-galactose
ADP + 6-deoxy-L-galactose 1-phosphate
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i.e. L-fucose, serves to utilize free L-fucose for glycoprotein synthesis
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?
ATP + L-fucose
ADP + beta-L-fucose 1-phosphate
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?
ATP + L-fucose
ADP + beta-L-fucose 1-phosphate
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involved in GDP-L-fucose salvage pathway
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?
ATP + L-fucose
ADP + beta-L-fucose 1-phosphate
involved in GDP-L-fucose salvage pathway
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-
?
ATP + L-fucose
ADP + beta-L-fucose 1-phosphate
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involved in GDP-L-fucose salvage pathway
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?
additional information
?
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development of an alternative way of labeling of fucosylated structures by metabolic engineering for the identification of fucosylated glycoproteins, using a chemoenzymatic approach. In this approach, the activities of Bacteroides fragilis 9343 L-fucokinase/guanosine-5'-diphosphate-Fuc pyrophosphorylase and human alpha1,3-fucosyltransferase 9 are combined in a Namalwa cellular model, the system can be applied to labeling of alkyne-modified fucosylated glycoproteins, e.g. for labeling of alkynyl fucose containing glycans, N-linked glycosylation site mapping and fucosylated glycoprotein identification by IGOT-LC-MS analysis, overview
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?
additional information
?
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development of an alternative way of labeling of fucosylated structures by metabolic engineering for the identification of fucosylated glycoproteins, using a chemoenzymatic approach. In this approach, the activities of Bacteroides fragilis 9343 L-fucokinase/guanosine-5'-diphosphate-Fuc pyrophosphorylase and human alpha1,3-fucosyltransferase 9 are combined in a Namalwa cellular model, the system can be applied to labeling of alkyne-modified fucosylated glycoproteins, e.g. for labeling of alkynyl fucose containing glycans, N-linked glycosylation site mapping and fucosylated glycoprotein identification by IGOT-LC-MS analysis, overview
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additional information
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fucokinase:GDP-fucose pyrophosphorylase is a dual activity enzyme metabolizing fucose and nucleotide-sugar
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