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2.7.1.6: galactokinase

This is an abbreviated version!
For detailed information about galactokinase, go to the full flat file.

Word Map on EC 2.7.1.6

Reaction

ATP
+
alpha-D-galactose
=
ADP
 +
alpha-D-galactose 1-phosphate

Synonyms

atgalk, ATP:D-galactose-1-phosphotransferase, BiGalK, CLB.507001.110, CLB.510667.120, GAL1, Gal1p, galactokinase, galactokinase 1, galactose kinase, GALK, GALK1, GalKAmu, GalKSpe4, kinase (phosphorylating), galacto-, kinase, galacto- (phosphorylating), SCO3136

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.6 galactokinase

Specific Activity

Specific Activity on EC 2.7.1.6 - galactokinase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.0043
-
mutant R36K, synthesis of ATP, pH 8.0, 24°C
0.0067
-
mutant R36A, synthesis of ATP, pH 8.0, 24°C
0.07
-
R37A mutant protein, substrate: galactose
0.0781
-
substrate: ATP + 6-deoxy-D-galactose, pH 8, 37°C
0.08
-
mutant R36A, synthesis of galactose 1-phosphate, pH 8.0, 24°C
0.0812
-
-
0.09
-
substrate: ATP + D-galacturonic acid, pH 8, 37°C
0.1
-
mutant R36K, synthesis of galactose 1-phosphate, pH 8.0, 24°C
0.14
-
Y109F mutant protein, substrate: galactose
0.15
-
-
0.17
-
Y236F mutant protein, substrate: galactose
0.43
-
wild-type, synthesis of ATP, pH 8.0, 24°C
0.52
-
substrate: UTP + D-galactose, pH 8, 37°C
0.551
-
substrate: CTP + D-galactose, pH 8, 37°C
0.61
-
mutant Y223H
0.63
-
mutant Y223R
0.65
-
mutant Y223L
0.87
-
mutant Y223W
0.91
-
wild-type protein, substrate: galactose
0.931
-
substrate: dCTP + D-galactose, pH 8, 37°C
1.14
-
Y109H mutant protein, substrate: galactose
1.5
-
substrate: dUTP + D-galactose, pH 8, 37°C
1.62
-
enzyme from erythrocyte
1.737
-
enzyme from placenta
11.5
-
wild-type, synthesis of galactose 1-phosphate, pH 8.0, 24°C
12.5
-
substrate: ATP + D-galactosamine, pH 8, 37°C
137
-
substrate: ATP + D-galactose, pH 8, 37°C
138
-
substrate: dATP + D-galactose, pH 8, 37°C
15.7
-
substrate: ITP + D-galactose, pH 8, 37°C
158
-
substrate: ATP + D-galactose, pH 8, 37°C
2.258
-
-
2.5
-
substrate: dTTP + D-galactose, pH 8, 37°C
23.42
-
mutant Y223F
23.5
-
wild-type
28.5
-
substrate: GTP + D-galactose, pH 8, 37°C
31.9
-
substrate: dGTP + D-galactose, pH 8, 37°C
99.7
-
substrate: ATP + 2-deoxy-D-galactose, pH 8, 37°C
additional information