2.7.1.63: polyphosphate-glucose phosphotransferase

This is an abbreviated version!
For detailed information about polyphosphate-glucose phosphotransferase, go to the full flat file.

Word Map on EC 2.7.1.63

2.7.1.63

mycobacterium

tuberculosis

6-phosphate

glucokinases

shermanii

propionibacterium

nonprocessive

synthesis

Reaction

Synonyms

All1371, GMK, inorganic polyphosphate/ATP-glucomannokinase, inorganic polyphosphate:D-glucose 6-phosphotransferase, More, PGPTase, phosphotransferase, polyphosphate-glucose, poly P glucokinase, poly(P) glucokinase, poly(P)/ATP-glucomannokinase, PolyP-dependent glucokinase, polyP-GK, polyP-Glk, polyphosphate glucokinase, polyphosphate-D-(+)-glucose-6-phosphotransferase, polyphosphate-dependent glucokinase, polyphosphate-glucose 6-phosphotransferase, polyphosphate/ATP-glucomannokinase, PP-Glk, PPGK, SCO5059

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.1 Phosphotransferases with an alcohol group as acceptor

2.7.1.63 polyphosphate-glucose phosphotransferase

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Results	in table
5	Activating Compound
875	AA Sequence
3	Application
1	CAS Registry Number
13	Cloned(Commentary)
1	Crystallization (Commentary)
9	General Information
4	General Stability
20	Inhibitors
22	kcat/KM [mM/s]
4	Ki Value [mM]
75	KM Value [mM]
4	Localization
19	Metals/Ions
29	Molecular Weight [Da]
19	Natural Substrates/ Products (Substrates)
57	Organism
5	Pathway
2	PDB ID
9	pH Optimum
5	pH Range
3	pH Stability
1	pI Value
5	Protein Variants
19	Purification (Commentary)
5	Reaction
1	Reaction Type
48	Reference
8	Specific Activity [micromol/min/mg]
1	Storage Stability
135	Substrates and Products (Substrate)
31	Subunits
69	Synonyms
1	Systematic Name
10	Temperature Optimum [°C]
1	Temperature Range [°C]
16	Temperature Stability [°C]
53	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 2.7.1.63 - polyphosphate-glucose phosphotransferase

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ADP

4 entries

AMP

3 entries

ATP

Mycobacterium tuberculosis

at high concentrations competitive substrate inhibition with respect to glucose, ATP-dependent reaction

641751

D-fructose 6-phosphate

Mycobacterium tuberculosis

inhibits reaction with polyphosphate and glucose or ATP and glucose

641751

D-glucose

Mycolicibacterium phlei

above 150 mM, substrate inhibition

641744

D-glucose 6-phosphate

2 entries

D-xylose

2 entries

Mg2+

Mycolicibacterium phlei

molar ratio polyphosphate/Mg below 0.5, activation above, EDTA partially reverses

641744

NaCl

Nocardia minima

above 100 mM

641747

Poly(P)

Mycolicibacterium phlei

above 0.05 mM, substrate inhibition

641744

Tetrapolyphosphate

Propionibacterium freudenreichii subsp. shermanii

inhibits reaction with ATP

641750

tripolyphosphate

Mycolicibacterium phlei

when present in excess together with Grahams salt at pH 7.2

641743

additional information

Corynebacterium glutamicum

A0A160PRJ4

no effect by fructose 1,6-bisphosphate, xylose, cAMP, UDP glucose, and glucose 1,6-bisphosphate

721367