2.7.1.66: undecaprenol kinase
This is an abbreviated version!
For detailed information about undecaprenol kinase, go to the full flat file.
Reaction
Synonyms
C55-isoprenoid alcohol kinase, C55-isoprenoid alcohol phosphokinase, C55-isoprenyl alcohol phosphokinase, DGKA, isoprenoid alcohol kinase, isoprenoid alcohol phosphokinase, isoprenoid-alcohol kinase, kinase (phosphorylating), isoprenoid alcohol, kinase, isoprenoid alcohol (phosphorylating), polyisoprenol kinase, UDPK, undecaprenyl phosphokinase, UOH kinase, Upk
ECTree
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Activating Compound
Activating Compound on EC 2.7.1.66 - undecaprenol kinase
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Detergents
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overview: activation by detergents, only neutral detergents with short chain and unsaturated chain hydrophobes are successful activators at 25°C
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requirements for endogenous and exogenous phospholipids. Enzyme requires a fluid lipid surface for activity, lysophosphatidylglycerol and ditetradecanoylphosphatidylcholine are the best activators
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Phospholipid cofactor
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absolute requirement for a phospholipid cofactor, mixture of phosphatidylglycerol and cardiolipin, either of which is effective alone in restoring the activity of the enzyme
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Phospholipid cofactor
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lipid requirement of the enzyme is nonelectrostatic in nature
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Phospholipid cofactor
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absolute requirement for phospholipid and for detergent
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Phospholipid cofactor
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overview: activation by commercial phospholipids and glycolipids, lipids providing a hydrated, loosely packed, highly fluid environment are often effective activators
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Phospholipid cofactor
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reactivation of apoprotein by synthetic lecithins
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