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2.7.1.78: polynucleotide 5'-hydroxyl-kinase

This is an abbreviated version!
For detailed information about polynucleotide 5'-hydroxyl-kinase, go to the full flat file.

Word Map on EC 2.7.1.78

Reaction

ATP
+
5'-dephospho-DNA
=
ADP
+
5'-phospho-DNA

Synonyms

5' end-specific RNA/DNA kinase, 5' polynucleotide kinase, 5'-hydroxyl polynucleotide kinase, 5'-hydroxyl polyribonucleotide kinase, 5'-hydroxyl RNA kinase, 5'-OH polynucleotide kinase, ATP:5'-dephosphopolynucleotide 5'-phosphatase, cleavage and polyadenylation factor I subunit, CLP1, Clp1-like protein, DNA 5'-hydroxyl kinase, DNA kinase, Grc3, HD-Pnk, HEAB, hPNKP, kinase (phosphorylating), polynucleotide 5'-hydroxyl, More, mPNKP, Nol9, PALF, PhoClp1, PNK, Pnk1, PNKP, polynucleotide 5'-hydroxyl kinase (phosphorylating), polynucleotide 5'-hydroxyl-kinase, polynucleotide kinase, polynucleotide kinase and aprataxin-like forkhead-associated, polynucleotide kinase phosphatase, polynucleotide kinase-phosphatase, polynucleotide kinase/phosphatase, RNA-specific polynucleotide kinase, Rnl1, RPNK, T4 PNK, T4 polynucleotide kinase, T4 polynucleotide kinase/phosphatase, tRNA endonuclease complex, TSEN

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.78 polynucleotide 5'-hydroxyl-kinase

Reference

Reference on EC 2.7.1.78 - polynucleotide 5'-hydroxyl-kinase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Habraken, Y.; Verly, W.G.
Further purification and characterization of the DNA 3-phosphatase from rat-liver chromatin which is also a polynucleotide 5-hydroxyl kinase
Eur. J. Biochem.
171
59-66
1988
Rattus norvegicus
Manually annotated by BRENDA team
Habraken, Y.; Verly, W.G.
The DNA 3-phosphatase and 5-hydroxyl kinase of rat liver chromatin
FEBS Lett.
160
46-50
1983
Rattus norvegicus
Manually annotated by BRENDA team
Maunders, M.J.
Polynucleotide kinase (EC 2.7.1.78)
Methods Mol. Biol.
16
343-357
1993
Escherichia phage T2, Tequatrovirus T4, Enterobacteria phage T6, Bos taurus, Homo sapiens, Mesocricetus auratus, no activity in Escherichia coli, Rattus norvegicus
Manually annotated by BRENDA team
Novogrodsky, A.; Hurwitz, J.
The enzymatic phosphorylation of ribonucleic acid and deoxyribonucleic acid. I. Phosphorylation at 5-hydroxyl termini
J. Biol. Chem.
241
2923-2932
1966
Escherichia phage T2, Tequatrovirus T4, no activity in bacteriophage T1, no activity in bacteriophage T5
Manually annotated by BRENDA team
Novogrodsky, A.; Tal, M.; Traub, A.; Hurwitz, J.
The enzymatic phosphorylation of ribonucleic acid and deoxyribonucleic acid. II. Further properties of the 5-hydroxyl polynucleotide kinase
J. Biol. Chem.
241
2933-2943
1966
Escherichia phage T2
Manually annotated by BRENDA team
Fejes, E.; Denes, G.
Purification and some properties of polynucleotide kinase from rat liver nuclei
Acta Biochim. Biophys. Acad. Sci. Hung.
15
275-285
1980
Rattus norvegicus
Manually annotated by BRENDA team
Panet, A.; van de Sande, J.H.; Loewen, P.C.; Khorana, H.G.; Raae, A.J.; Lillehaug, J.R.; Kleppe, K.
Physical characterization and simultaneous purification of bacteriophage T4 induced polynucleotide kinase, polynucleotide ligase, and deoxyribonucleic acid polymerase
Biochemistry
12
5045-5050
1973
Tequatrovirus T4
Manually annotated by BRENDA team
Lillehaug, J.R.; Kleppe, R.K.; Kleppe, K.
Phosphorylation of double-stranded DNAs by T4 polynucleotide kinase
Biochemistry
15
1858-1865
1976
Tequatrovirus T4
Manually annotated by BRENDA team
Teraoka, H.; Mizuta, K.; Sato, F.; Shimoyachi, M.; Tsukada, K.
Polynucleotide kinase from rat-liver nuclei. Purification and properties
Eur. J. Biochem.
58
297-302
1975
Rattus norvegicus
Manually annotated by BRENDA team
Lillehaug, J.R.
Physicochemical properties of T4 polynucleotide kinase
Eur. J. Biochem.
73
499-506
1977
Tequatrovirus T4
Manually annotated by BRENDA team
Tamura, S.; Teraoka, H.; Tsukada, K.
Characterization of DNA kinase from calf thymus
Eur. J. Biochem.
115
449-453
1981
Bos taurus
Manually annotated by BRENDA team
Nichols, B.P.; Lindell, T.D.; Stellwagen, E.; Donelson, J.E.
A rapid purification of T4 polynucleotide kinase using Blue Dextran-Sepharose chromatography
Biochim. Biophys. Acta
526
410-417
1978
Tequatrovirus T4
Manually annotated by BRENDA team
Lillehaug, J.R.
Inhibition of T4 polynucleotide kinase by the ATP analog, beta, gamma-imidoadenylyl 5-triphosphate
Biochim. Biophys. Acta
525
357-363
1978
Tequatrovirus T4
Manually annotated by BRENDA team
Pheiffer, B.H.; Zimmerman, S.B.
Deoxyribonucleic acid kinase from nuclei of rat liver: mechanism, reversal, and inhibitors of the reaction
Biochemistry
18
2960-2963
1979
Rattus norvegicus
Manually annotated by BRENDA team
Sertic-Pritsos, K.; Vinocour, M.; Winicov, I.
5-Hydroxyl RNA kinase from mouse L cells
Eur. J. Biochem.
144
47-55
1984
Mus musculus
Manually annotated by BRENDA team
Soltis, D.A.; Uhlenbeck, O.C.
Isolation and characterization of two mutant forms of T4 polynucleotide kinase
J. Biol. Chem.
257
11332-11339
1982
Tequatrovirus T4
Manually annotated by BRENDA team
Bosdal, T.; Lillehaug, J.R.
Purification and kinetic properties of polynucleotide kinase from rat testes
Biochim. Biophys. Acta
840
280-286
1985
Rattus norvegicus
Manually annotated by BRENDA team
Shuman, S.; Hurwitz, J.
5-Hydroxyl polyribonucleotide kinase from HeLa cell nuclei. Purification and properties
J. Biol. Chem.
254
10396-10404
1979
Homo sapiens
Manually annotated by BRENDA team
Levin, C.J.; Zimmerman, S.B.
A deoxyribonucleic acid kinase from nuclei of rat liver. Purification and properties
J. Biol. Chem.
251
1767-1774
1976
Rattus norvegicus
Manually annotated by BRENDA team
Austin, G.E.; Sirakoff, D.; Roop, B.; Moyer, G.H.
Purification and properties of polynucleotide kinase of calf thymus
Biochim. Biophys. Acta
522
412-422
1978
Bos taurus
Manually annotated by BRENDA team
Lorsch, J.R.; Szostak, J.W.
Kinetic and thermodynamic characterization of the reaction catalyzed by a polynucleotide kinase ribozyme
Biochemistry
34
15315-15327
1995
synthetic ribozyme
Manually annotated by BRENDA team
Prinos, P.; Slack, C.; Lasko, D.D.
5' Phosphorylation of DNA in mammalian cells: identification of a polymin P-precipitable polynucleotide kinase
J. Cell. Biochem.
58
115-131
1995
Bos taurus
Manually annotated by BRENDA team
Karimi-Busheri, F.; Weinfeld, M.
Purification and substrate specificity of polydeoxyribonucleotide kinases isolated from calf thymus and rat liver
J. Cell. Biochem.
64
258-272
1997
Bos taurus, Rattus norvegicus
Manually annotated by BRENDA team
Fanta, M.; Zhang, H.; Bernstein, N.; Glover, M.; Karimi-Busheri, F.; Weinfeld, M.
Production, characterization, and epitope mapping of monoclonal antibodies against human polydeoxyribonucleotide kinase
Hybridoma
20
237-242
2001
Homo sapiens
Manually annotated by BRENDA team
Wang, L.K.; Shuman, S.
Mutational analysis defines the 5'-kinase and 3'-phosphatase active sites of T4 polynucleotide kinase
Nucleic Acids Res.
30
1073-1080
2002
Tequatrovirus T4
Manually annotated by BRENDA team
Petrousseva, I.O.; Safronov, I.V.; Komarova, N.I.; Kamynina, T.P.; Lavrik, O.I.; Khodyreva, S.N.
A new approach to the synthesis of the 5'-end substituted oligonucleotides using T4 polynucleotide kinase and gamma-amides of ATP bearing photoreactive groups
Dokl. Biochem. Biophys.
389
114-117
2003
Tequatrovirus T4
Manually annotated by BRENDA team
Caldecott, K.W.
Polynucleotide kinase. A versatile molecule makes a clean break
Structure
10
1151-1152
2002
Tequatrovirus T4, Mammalia
Manually annotated by BRENDA team
Zhu, H.; Yin, S.; Shuman, S.
Characterization of polynucleotide kinase/phosphatase enzymes from Mycobacteriophages omega and Cjw1 and vibriophage KVP40
J. Biol. Chem.
279
26358-26369
2004
Omegavirus omega, Kostyavirus CJW1
Manually annotated by BRENDA team
Mani, R.S.; Karimi-Busheri, F.; Fanta, M.; Cass, C.E.; Weinfeld, M.
Spectroscopic studies of DNA and ATP binding to human polynucleotide kinase: evidence for a ternary complex
Biochemistry
42
12077-12084
2003
Homo sapiens
Manually annotated by BRENDA team
Martins, A.; Shuman, S.
Characterization of a baculovirus enzyme with RNA ligase, polynucleotide 5'-Kinase, and polynucleotide 3'-phosphatase activities
J. Biol. Chem.
279
18220-18231
2004
unidentified baculovirus
Manually annotated by BRENDA team
Blondal, T.; Hjorleifsdottir, S.; Aevarsson, A.; Fridjonsson, O.H.; Skirnisdottir, S.; Wheat, J.O.; Hermannsdottir, A.G.; Hreggvidsson, G.O.; Smith, A.V.; Kristjansson, J.K.
Characterization of a 5'-polynucleotide kinase/3'-phosphatase from bacteriophage RM378
J. Biol. Chem.
280
5188-5194
2005
Rhodothermus phage RM378
Manually annotated by BRENDA team
Bernstein, N.K.; Williams, R.S.; Rakovszky, M.L.; Cui, D.; Green, R.; Karimi-Busheri, F.; Mani, R.S.; Galicia, S.; Koch, C.A.; Cass, C.E.; Durocher, D.; Weinfeld, M.; Glover, J.N.
The molecular architecture of the mammalian DNA repair enzyme, polynucleotide kinase
Mol. Cell
17
657-670
2005
Mus musculus (Q9JLV6)
Manually annotated by BRENDA team
Eastberg, J.H.; Pelletier, J.; Stoddard, B.L.
Recognition of DNA substrates by T4 bacteriophage polynucleotide kinase
Nucleic Acids Res.
32
653-660
2004
Tequatrovirus T4 (P06855)
Manually annotated by BRENDA team
Karimi-Busheri, F.; Rasouli-Nia, A.; Allalunis-Turner, J.; Weinfeld, M.
Human polynucleotide kinase participates in repair of DNA double-strand breaks by nonhomologous end joining but not homologous recombination
Cancer Res.
67
6619-6625
2007
Homo sapiens
Manually annotated by BRENDA team
Keppetipola, N.; Shuman, S.
Distinct enzymic functional groups are required for the phosphomonoesterase and phosphodiesterase activities of Clostridium thermocellum polynucleotide kinase/phosphatase
J. Biol. Chem.
281
19251-19259
2006
Acetivibrio thermocellus
Manually annotated by BRENDA team
Audebert, M.; Salles, B.; Weinfeld, M.; Calsou, P.
Involvement of polynucleotide kinase in a poly(ADP-ribose) polymerase-1-dependent DNA double-strand breaks rejoining pathway
J. Mol. Biol.
356
257-265
2006
Homo sapiens
Manually annotated by BRENDA team
Dobson, C.J.; Allinson, S.L.
The phosphatase activity of mammalian polynucleotide kinase takes precedence over its kinase activity in repair of single strand breaks
Nucleic Acids Res.
34
2230-2237
2006
Homo sapiens
Manually annotated by BRENDA team
Keppetipola, N.; Shuman, S.
Mechanism of the phosphatase component of Clostridium thermocellum polynucleotide kinase-phosphatase
RNA
12
73-82
2006
Acetivibrio thermocellus
Manually annotated by BRENDA team
Keppetipola, N.; Shuman, S.
Characterization of the 2,3 cyclic phosphodiesterase activities of Clostridium thermocellum polynucleotide kinase-phosphatase and bacteriophage lambda phosphatase
Nucleic Acids Res.
35
7721-7732
2007
Acetivibrio thermocellus
Manually annotated by BRENDA team
Song, C.; Zhao, M.
Real-time monitoring of the activity and kinetics of T4 polynucleotide kinase by a singly labeled DNA-hairpin smart probe coupled with lambda exonuclease cleavage
Anal. Chem.
81
1383-1388
2009
Tequatrovirus T4 (P06855)
Manually annotated by BRENDA team
Freschauf, G.K.; Karimi-Busheri, F.; Ulaczyk-Lesanko, A.; Mereniuk, T.R.; Ahrens, A.; Koshy, J.M.; Rasouli-Nia, A.; Pasarj, P.; Holmes, C.F.; Rininsland, F.; Hall, D.G.; Weinfeld, M.
Identification of a small molecule inhibitor of the human DNA repair enzyme polynucleotide kinase/phosphatase
Cancer Res.
69
7739-7746
2009
Tequatrovirus T4, Homo sapiens, Schizosaccharomyces pombe, Mus musculus (Q9JLV6)
Manually annotated by BRENDA team
Whiteside, J.R.; Box, C.L.; McMillan, T.J.; Allinson, S.L.
Cadmium and copper inhibit both DNA repair activities of polynucleotide kinase
DNA Repair
9
83-89
2010
Homo sapiens
Manually annotated by BRENDA team
Freschauf, G.K.; Mani, R.S.; Mereniuk, T.R.; Fanta, M.; Virgen, C.A.; Dianov, G.L.; Grassot, J.M.; Hall, D.G.; Weinfeld, M.
Mechanism of action of an imido-piperidine inhibitor of human polynucleotide kinase/phosphatase
J. Biol. Chem.
285
2351-2360
2010
Homo sapiens (Q96T60)
Manually annotated by BRENDA team
Jain, R.; Shuman, S.
Characterization of a thermostable archaeal polynucleotide kinase homologous to human Clp1
RNA
15
923-931
2009
Pyrococcus horikoshii (Q57936), Pyrococcus horikoshii
Manually annotated by BRENDA team
Weinfeld, M.; Mani, R.S.; Abdou, I.; Aceytuno, R.D.; Glover, J.N.
Tidying up loose ends: the role of polynucleotide kinase/phosphatase in DNA strand break repair
Trends Biochem. Sci.
36
262-271
2011
Tequatrovirus T4, Homo sapiens, Mus musculus, Schizosaccharomyces pombe
Manually annotated by BRENDA team
Heindl, K.; Martinez, J.
Nol9 is a novel polynucleotide 5-kinase involved in ribosomal RNA processing
EMBO J.
29
4161-4171
2010
Homo sapiens
Manually annotated by BRENDA team
Li, S.; Kanno, S.; Watanabe, R.; Ogiwara, H.; Kohno, T.; Watanabe, G.; Yasui, A.; Lieber, M.R.
Polynucleotide kinase and aprataxin-like forkhead-associated protein (PALF) acts as both a single-stranded DNA endonuclease and a single-stranded DNA 3 exonuclease and can participate in DNA end joining in a biochemical system
J. Biol. Chem.
286
36368-36377
2011
Homo sapiens
Manually annotated by BRENDA team
Schellenberg, M.; Williams, R.
DNA end processing by polynucleotide kinase/phosphatase
Proc. Natl. Acad. Sci. USA
108
20855-20856
2011
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Durand, S.; Richard, G.; Bontems, F.; Uzan, M.
Bacteriophage T4 polynucleotide kinase triggers degradation of mRNAs
Proc. Natl. Acad. Sci. USA
109
7073-7078
2012
Tequatrovirus T4
Manually annotated by BRENDA team
Wang, L.K.; Das, U.; Smith, P.; Shuman, S.
Structure and mechanism of the polynucleotide kinase component of the bacterial Pnkp-Hen1 RNA repair system
RNA
18
2277-2286
2012
Acetivibrio thermocellus (A3DJ38), Acetivibrio thermocellus
Manually annotated by BRENDA team
Mair, B.; Popow, J.; Mechtler, K.; Weitzer, S.; Martinez, J.
Intron excision from precursor tRNA molecules in mammalian cells requires ATP hydrolysis and phosphorylation of tRNA-splicing endonuclease components
Biochem. Soc. Trans.
41
831-837
2013
Homo sapiens
Manually annotated by BRENDA team
Karaca, E.; Weitzer, S.; Pehlivan, D.; Shiraishi, H.; Gogakos, T.; Hanada, T.; Jhangiani, S.N.; Wiszniewski, W.; Withers, M.; Campbell, I.M.; Erdin, S.; Isikay, S.; Franco, L.M.; Gonzaga-Jauregui, C.; Gambin, T.; Gelowani, V.; Hunter, J.V.; Yesil, G.; Koparir, E.; Yilmaz, S.; Brown, M.; Briskin, D.; H, H.a.
Human CLP1 mutations alter tRNA biogenesis, affecting both peripheral and central nervous system function
Cell
157
636-650
2014
Homo sapiens
Manually annotated by BRENDA team
Schaffer, A.E.; Eggens, V.R.; Caglayan, A.O.; Reuter, M.S.; Scott, E.; Coufal, N.G.; Silhavy, J.L.; Xue, Y.; Kayserili, H.; Yasuno, K.; Rosti, R.O.; Abdellateef, M.; Caglar, C.; Kasher, P.R.; Cazemier, J.L.; Weterman, M.A.; Cantagrel, V.; Cai, N.; Zweier, C.; Altunoglu, U.; Satkin, N.B.; Aktar, F.; Tuysuz, B.
CLP1 founder mutation links tRNA splicing and maturation to cerebellar development and neurodegeneration
Cell
157
651-663
2014
Homo sapiens (Q92989), Homo sapiens
Manually annotated by BRENDA team
Das, U.; Shuman, S.
Mechanism of RNA 2,3-cyclic phosphate end healing by T4 polynucleotide kinase-phosphatase
Nucleic Acids Res.
41
355-365
2013
Tequatrovirus T4
Manually annotated by BRENDA team
Ma, C.; Fang, H.; Wang, K.; Xia, K.; Chen, H.; He, H.; Zeng, W.
Simultaneous detection of kinase and phosphatase activities of polynucleotide kinase using molecular beacon probes
Anal. Biochem.
443
166-168
2013
Tequatrovirus T4
Manually annotated by BRENDA team
Tao, M.; Shi, Z.; Cheng, R.; Zhang, J.; Li, B.; Jin, Y.
Highly specific fluorescence detection of T4 polynucleotide kinase activity via photo-induced electron transfer
Anal. Biochem.
485
18-24
2015
Tequatrovirus T4
Manually annotated by BRENDA team
Hou, T.; Wang, X.; Liu, X.; Lu, T.; Liu, S.; Li, F.
Amplified detection of T4 polynucleotide kinase activity by the coupled lambda exonuclease cleavage reaction and catalytic assembly of bimolecular beacons
Anal. Chem.
86
884-890
2014
Tequatrovirus T4
Manually annotated by BRENDA team
Wang, G.; Chen, L.; He, X.; Zhu, Y.; Zhang, X.
Detection of polynucleotide kinase activity by using a gold electrode modified with magnetic microspheres coated with titanium dioxide nanoparticles and a DNA dendrimer
Analyst
139
3895-3900
2014
Tequatrovirus T4
Manually annotated by BRENDA team
Zhou, F.; Wang, G.; Shi, D.; Sun, Y.; Sha, L.; Qiu, Y.; Zhang, X.
One-strand oligonucleotide probe for fluorescent label-free "turn-on" detection of T4 polynucleotide kinase activity and its inhibition
Analyst
140
5650-5655
2015
Tequatrovirus T4
Manually annotated by BRENDA team
Strazdaite-Zieliene, Z.; Zajanckauskaite, A.; Kaliniene, L.; Meskys, R.; Truncaite, L.
A mutation in the gene for polynucleotide kinase of bacteriophage T4 K10 affects mRNA processing
Arch. Virol.
159
327-331
2014
Tequatrovirus T4, Tequatrovirus T4 K10
Manually annotated by BRENDA team
Das, U.; Wang, L.K.; Smith, P.; Shuman, S.
Structural and biochemical analysis of the phosphate donor specificity of the polynucleotide kinase component of the bacterial pnkp-hen1 RNA repair system
Biochemistry
52
4734-4743
2013
Acetivibrio thermocellus (A3DJ38), Acetivibrio thermocellus
Manually annotated by BRENDA team
Zhang, L.; Zhao, J.; Zhang, H.; Jiang, J.; Yu, R.
Double strand DNA-templated copper nanoparticle as a novel fluorescence indicator for label-free detection of polynucleotide kinase activity
Biosens. Bioelectron.
44
6-9
2013
Tequatrovirus T4
Manually annotated by BRENDA team
Chen, F.; Zhao, Y.; Qi, L.; Fan, C.
One-step highly sensitive florescence detection of T4 polynucleotide kinase activity and biological small molecules by ligation-nicking coupled reaction-mediated signal amplification
Biosens. Bioelectron.
47
218-224
2013
Tequatrovirus T4
Manually annotated by BRENDA team
Lian, S.; Liu, C.; Zhang, X.; Wang, H.; Li, Z.
Detection of T4 polynucleotide kinase activity based on cationic conjugated polymer-mediated fluorescence resonance energy transfer
Biosens. Bioelectron.
66
316-320
2015
Tequatrovirus T4
Manually annotated by BRENDA team
Das, U.; Wang, L.K.; Smith, P.; Munir, A.; Shuman, S.
Structures of bacterial polynucleotide kinase in a Michaelis complex with nucleoside triphosphate (NTP)-Mg2+ and 5-OH RNA and a mixed substrate-product complex with NTP-Mg2+ and a 5-phosphorylated oligonucleotide
J. Bacteriol.
196
4285-4292
2014
Acetivibrio thermocellus (A3DJ38), Acetivibrio thermocellus, Acetivibrio thermocellus DSM 1237 (A3DJ38)
Manually annotated by BRENDA team
Dikfidan, A.; Loll, B.; Zeymer, C.; Magler, I.; Clausen, T.; Meinhart, A.
RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase Clp1
Mol. Cell
54
975-986
2014
Caenorhabditis elegans (P52874), Caenorhabditis elegans
Manually annotated by BRENDA team
Castle, C.; Sardana, R.; Dandekar, V.; Borgianini, V.; Johnson, A.; Denicourt, C.
Las1 interacts with Grc3 polynucleotide kinase and is required for ribosome synthesis in Saccharomyces cerevisiae
Nucleic Acids Res.
41
1135-1150
2013
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Ma, C.; Jin, S.; Wang, J.; Wang, K.; Liu, H.; Wu, K.
A fluorescence-based assay for T4 polynucleotide kinase/phosphatase activity based on a terminal transferase-aided photoinduced electron transfer strategy
Anal. Methods
8
1989-1994
2016
Tequatrovirus T4 (P06855)
-
Manually annotated by BRENDA team
Shimada, M.; Dumitrache, L.C.; Russell, H.R.; McKinnon, P.J.
Polynucleotide kinase-phosphatase enables neurogenesis via multiple DNA repair pathways to maintain genome stability
EMBO J.
34
2465-2480
2015
Mus musculus (Q9JLV6)
Manually annotated by BRENDA team
Zhang, X.; Liu, Q.; Jin, Y.; Li, B.
Determination of the activity of T4 polynucleotide kinase phosphatase by exploiting the sequence-dependent fluorescence of DNA-templated copper nanoclusters
Microchim. Acta
186
003
2019
Tequatrovirus T4 (P06855)
Manually annotated by BRENDA team
Chatterjee, A.; Saha, S.; Chakraborty, A.; Silva-Fernandes, A.; Mandal, S.M.; Neves-Carvalho, A.; Liu, Y.; Pandita, R.K.; Hegde, M.L.; Hegde, P.M.; Boldogh, I.; Ashizawa, T.; Koeppen, A.H.; Pandita, T.K.; Maciel, P.; Sarkar, P.S.; Hazra, T.K.
The role of the mammalian DNA end-processing enzyme polynucleotide kinase 3-phosphatase in spinocerebellar ataxia type 3 pathogenesis
PLoS Genet.
11
e1004749
2015
Homo sapiens
Manually annotated by BRENDA team
Dong, Z.; Zhang, L.; Qiao, M.; Ge, J.; Liu, A.; Li, Z.
A label-free assay for T4 polynucleotide kinase/phosphatase activity and its inhibitors based on poly(thymine)-templated copper nanoparticles
Talanta
146
253-258
2015
Tequatrovirus T4 (P06855)
Manually annotated by BRENDA team
Zhang, H.; Zhao, Z.; Lei, Z.; Wang, Z.
Sensitive detection of polynucleotide kinase activity by paper-based fluorescence assay with lambda exonuclease assistance
Anal. Chem.
88
11358-11363
2016
Tequatrovirus T4
Manually annotated by BRENDA team
Feng, C.; Wang, Z.; Chen, T.; Chen, X.; Mao, D.; Zhao, J.; Li, G.
A dual-enzyme-assisted three-dimensional DNA walking machine using T4 polynucleotide kinase as activators and application in polynucleotide kinase assays
Anal. Chem.
90
2810-2815
2018
Tequatrovirus T4
Manually annotated by BRENDA team
Munir, A.; Shuman, S.
Characterization of Runella slithyformis HD-Pnk, a bifunctional DNA/RNA end-healing enzyme composed of an N-terminal 2,3-phosphoesterase HD domain and a C-terminal 5'-OH polynucleotide kinase domain
J. Bacteriol.
199
e00739-16
2017
Runella slithyformis, Runella slithyformis ATCC 49304
Manually annotated by BRENDA team
Tsukada, K.; Matsumoto, Y.; Shimada, M.
Linker region is required for efficient nuclear localization of polynucleotide kinase phosphatase
PLoS ONE
15
e0239404
2020
Homo sapiens
Manually annotated by BRENDA team