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2.7.1.81: hydroxylysine kinase

This is an abbreviated version!
For detailed information about hydroxylysine kinase, go to the full flat file.

Word Map on EC 2.7.1.81

Reaction

GTP
+
5-hydroxy-L-lysine
=
GDP
 +
5-phosphooxy-L-lysine

Synonyms

AGPHD1, guanosine triphosphate:5-hydroxy-L-lysine O-phosphotransferase, hydroxylysine kinase (phosphorylating), kinase, hydroxylysine (phosphorylating)

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.81 hydroxylysine kinase

Inhibitors

Inhibitors on EC 2.7.1.81 - hydroxylysine kinase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-Amino-5-hydroxyadipate
-
4 isomers, 40 mM, strong inhibition
4,5-Dehydro-(trans)-L-lysine
-
-
carnitine
-
2 isomers
choline
D-ornithine
-
-
ethanolamine
Hydroxy-L-pipecolate
-
-
-
hydroxy-L-proline
-
40 mM, strong
L-2,4-diamino-n-butyrate
-
-
L-homoserine
-
40 mM, weak inhibition
L-lysine
L-ornithine
Mn2+
-
at 1 mM, in presence of 1 mM Mg2+, strong inhibition, but activation in absence of Mg2+
S-aminoethyl-L-cysteine
-
-
Zn2+
-
at 1 mM, in presence of 1 mM Mg2+, strong inhibition
additional information
-
no inhibition by serine, threonine, and hydroxyproline
-