2.7.1.86: NADH kinase
This is an abbreviated version!
For detailed information about NADH kinase, go to the full flat file.
Reaction
Synonyms
ATP-NADH kinase, ATP:NADH 2'-phosphotransferase, ATP:NADH2 2'-phosphotransferase, diphosphopyridine nucleotide (reduced) kinase, DPNH kinase, EC 2.7.1.96, kinase, reduced nicotinamide adenine dinucleotide (phosphorylating), Mfnk, NAD(H) kinase, NAD(H)K, NADH kinase, NADH kinase POS5, mitochondrial, NADH2 kinase, NADHK, NADK, NADK-1, NADK1, NADK3, nicotinamide adenine dinucleotide (reduced) kinase, nicotinamide adenine dinucleotide hydride kinase, Pos5, Pos5p, Posp5, Ppnk, reduced diphosphopyridine nucleotide kinase, reduced nicotinamide adenine dinucleotide kinase (phosphorylating), Utr1, YEF1, YEL041W
ECTree
Advanced search results
General Information
General Information on EC 2.7.1.86 - NADH kinase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
malfunction
physiological function
-
yeast cells lacking the mitochondrial NADH kinase encoded by POS5 display increased sensitivity to hydrogen peroxide, a slow-growth phenotype, reduced mitochondrial function and increased levels of mitochondrial protein oxidation and mitochondrial DNA mutations
malfunction
-
deletion of the POS5 gene results in respiratory deficiency, anti-oxidative dysfunction and arginine auxotrophy of cells, and the respiratory deficiency is fatal for mitochondrial function
malfunction
-
DELTApos5 mitochondria cannot efficiently synthesize Fe-S clusters on endogenous aconitase or imported ferredoxin
malfunction
-
deletion of the POS5 gene results in respiratory deficiency, anti-oxidative dysfunction and arginine auxotrophy of cells, and the respiratory deficiency is fatal for mitochondrial function
-
malfunction
-
DELTApos5 mitochondria cannot efficiently synthesize Fe-S clusters on endogenous aconitase or imported ferredoxin
-
malfunction
-
yeast cells lacking the mitochondrial NADH kinase encoded by POS5 display increased sensitivity to hydrogen peroxide, a slow-growth phenotype, reduced mitochondrial function and increased levels of mitochondrial protein oxidation and mitochondrial DNA mutations
-
-
the enzyme contributes to the maintenance of respiratory chain complex activities
physiological function
-
the enzyme is required for efficient iron-sulfur cluster biogenesis in wild type mitochondria
physiological function
a triple mutant lacking the activities of ATP-NAD/NADH kinase Utr1, ATP-NADH kinase Pos5 and ATP-NADH kinase Yel041wp, i.e. Yef1, is viable and does not show growth defects. Presence of Utr1 protein is critical for growth in low iron medium
physiological function
the enzyme might have a role in waterlogging tolerance in legumes
physiological function
the enzyme might have a role in waterlogging tolerance in legumes
physiological function
-
the enzyme contributes to the maintenance of respiratory chain complex activities
-
physiological function
-
the enzyme is required for efficient iron-sulfur cluster biogenesis in wild type mitochondria
-