2.7.1.86: NADH kinase
This is an abbreviated version!
For detailed information about NADH kinase, go to the full flat file.
Reaction
Synonyms
ATP-NADH kinase, ATP:NADH 2'-phosphotransferase, ATP:NADH2 2'-phosphotransferase, diphosphopyridine nucleotide (reduced) kinase, DPNH kinase, EC 2.7.1.96, kinase, reduced nicotinamide adenine dinucleotide (phosphorylating), Mfnk, NAD(H) kinase, NAD(H)K, NADH kinase, NADH kinase POS5, mitochondrial, NADH2 kinase, NADHK, NADK, NADK-1, NADK1, NADK3, nicotinamide adenine dinucleotide (reduced) kinase, nicotinamide adenine dinucleotide hydride kinase, Pos5, Pos5p, Posp5, Ppnk, reduced diphosphopyridine nucleotide kinase, reduced nicotinamide adenine dinucleotide kinase (phosphorylating), Utr1, YEF1, YEL041W
ECTree
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Metals Ions
Metals Ions on EC 2.7.1.86 - NADH kinase
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Ca2+
K+
-
K+ is the only monovalent metal ion resulting higher NADH kinase activity by almost 1.5fold
Mg2+
Mn2+
Zn2+
additional information
no significant increase in NAD(H) kinase activity is detected in the presence of Ca2+ /calmodulin
Mg2+
-
Mn2+ can substitute for Mg2+ to stabilize the phosphoanhydride bonds of ATP but with only 28% of the activity. Km-value Mg2+, 1.16 mM
Mg2+
-
either Mn2+ or Mg2+ activate at low concentrations. Km: Km: 1.0 mM
-
Mn2+ can substitute for Mg2+ to stabilize the phosphoanhydride bonds of ATP but with only 28% of the activity