2.7.1.90: diphosphate-fructose-6-phosphate 1-phosphotransferase
This is an abbreviated version!
For detailed information about diphosphate-fructose-6-phosphate 1-phosphotransferase, go to the full flat file.
Word Map on EC 2.7.1.90
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2.7.1.90
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2,6-bisphosphate
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atp-pfks
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propionibacterium
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freudenreichii
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fructose-2,6-bisphosphate
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phosphofructokinases
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dikinase
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embden-meyerhof-parnas
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fowleri
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methanolica
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thermoproteus
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mgppi
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tenax
- 2.7.1.90
- 2,6-bisphosphate
- atp-pfks
- propionibacterium
- freudenreichii
- fructose-2,6-bisphosphate
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phosphofructokinases
- dikinase
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embden-meyerhof-parnas
- fowleri
- methanolica
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thermoproteus
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mgppi
- tenax
Reaction
Synonyms
6-phosphofructokinase (pyrophosphate), AtPFPalpha2, diphosphate-D-fructose-6-phosphate 1-phosphotransferase, FBPase, fructose 1,6-bisphosphatase, inorganic pyrophosphate-dependent phosphofructokinase, inorganic pyrophosphate-phosphofructokinase, PFKA, PFP, PfpA4, phosphotransferase, pyrophosphate-D-fructose 6-phosphate 1-, PPi-dependent 6-phosphofructokinase, PPi-dependent phosphofructokinase, PPi-PFK, pyrophosphate D-fructose-6-phosphate 1-phosphotransferase, pyrophosphate-D-fructose 6-phosphate 1-phosphotransferase, pyrophosphate-D-fructose 6-phosphate phosphotransferase, pyrophosphate-dependent 6-phosphofructokinase, pyrophosphate-dependent fructose-6-phosphate 1-phosphotransferase, pyrophosphate-dependent phosphofructo-1-kinase, pyrophosphate-dependent phosphofructokinase, pyrophosphate-fructose-6-phosphate-phosphotransferase, pyrophosphate: D-fructose-6-phosphate 1-phosphotransferase, pyrophosphate: fructose 6-phosphate 1-phosphotransferase, pyrophosphate: fructose-6-phosphate 1-phosphotransferase, pyrophosphate:D-fructose-6-phosphate 1-phosphotransferase, pyrophosphate:fructose 6-phosphate 1-phosphotransferase, pyrophosphate:fructose-6-phosphate 1-phosphotransferase
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2.7.1.90 diphosphate-fructose-6-phosphate 1-phosphotransferaseAdvanced search results
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results (Inhibitors
Inhibitors on EC 2.7.1.90 - diphosphate-fructose-6-phosphate 1-phosphotransferase
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INHIBITOR 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
2,5-Anhydro-D-mannitol 1,6-bisphosphate
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D-fructose 1,6-bisphosphate-analog, kinetics
3-[N-(2-phenylthioethyl)-N-methylamino]-1-hydroxypropylidene-1,1-bisphosphonate
i.e. CGP 48048, bisphosphonate, synthetic diphosphate analogue; inhibition of growth
alendronate
bisphosphonate, synthetic diphosphate analogue; inhibition of growth
clodronate
bisphosphonate, synthetic diphosphate analogue; inhibition of initial growth after inoculation
etidronate
bisphosphonate, synthetic diphosphate analogue; inhibition of growth
Increased ionic strength
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e.g. 30 mM KCl, NH4Cl, 10 mM Na2SO4, (NH4)2SO4 or 5 mM sodium phosphate
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KCl
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complete inhibition in the forward reaction, slightly inhibitory in the reverse reaction
magnesium diphosphate
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reverse reaction, product inhibition, kinetics
pamidronate
bisphosphonate, synthetic diphosphate analogue; inhibition of growth
risedronate
bisphosphonate, synthetic diphosphate analogue; inhibition of growth
zoledronate
bisphosphonate, synthetic diphosphate analogue; inhibition of initial growth after inoculation
1,n-Alkanediol biphosphates
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n: 2-9, weak
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2,3-O-isopropylidene-alpha-L-sorbofuranose-1-phosphate
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weak
3-phospho-D-glycerate
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diminishes the activating effect of fructose 2,6-bisphosphate
ADP
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50% inhibition in the forward reaction and complete inhibition in the reverse reaction at 1 mM
AMP
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90% inhibition in the forward reaction and complete inhibition in the reverse reaction at 1 mM
Ca2+
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complete inhibition in the forward reaction, slightly inhibitory in the reverse reaction
Co2+
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complete inhibition in the forward reaction, strong inhibition in the reverse reaction
D-fructose 1,6-bisphosphate
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forward reaction, product inhibition, kinetics
D-fructose 1,6-bisphosphate
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forward reaction, product inhibition, kinetics
D-fructose 2,6-bisphosphate
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competitive versus D-fructose 1,6-bisphosphate, reverse reaction
D-fructose 2,6-bisphosphate
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at high concentration; competitive versus D-fructose 1,6-bisphosphate, reverse reaction
D-fructose 6-phosphate
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competitive versus D-fructose 1,6-bisphosphate and phosphate
D-fructose 6-phosphate
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reverse reaction, product inhibition, kinetics
D-fructose 6-phosphate
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reverse reaction, diminishes the activating effect of fructose 2,6-bisphosphate
diphosphate
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kinetics; substrate-substrate interaction between phosphate and diphosphate in forward and reverse reaction
diphosphate
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reverse reaction, diminishes the activating effect of fructose 2,6-bisphosphate
Imidodiphosphate
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mixed inhibitor with respect to both fructose 6-phosphate and diphosphate
Mn2+
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inhibitory in the forward reaction only, slightly activating in the reverse reaction
NaCl
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complete inhibition in the forward reaction, slightly inhibitory in the reverse reaction
NH4+
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complete inhibition in the forward reaction, slightly inhibitory in the reverse reaction
phosphate
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noncompetitive versus diphosphate and D-fructose 6-phosphate; sequential ternary complex mechanism
phosphate
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in the forward reaction only in presence of fructose 2,6-bisphosphate
phosphate
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inhibitory in the reverse reaction; in the forward reaction only in presence of fructose 2,6-bisphosphate
phosphate
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forward reaction, product inhibition, kinetics; substrate-substrate interaction between phosphate and diphosphate in forward and reverse reaction
phosphate
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forward reaction, diminishes the activating effect of fructose 2,6-bisphosphate
phosphate
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in the forward reaction only in presence of fructose 2,6-bisphosphate
phosphoenolpyruvate
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diminishes the activating effect of fructose 2,6-bisphosphate
additional information
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no inhibition by ammonium sulfate, D-fructose 2,6-bisphosphate, GDP; no inhibition by nucleoside triphosphates
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additional information
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addition of citrate, pyruvate, phosphoenolpyruvate, L-serine, phosphoglycerate, ATP, ADP, AMP, NADP, NADs and NADPH to the assay mixture has no effect on activity
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additional information
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not affected by pyruvate, citrate, serine, phosphoglycerate, phosphoenolpyruvate, ATP, ADP, AMP, NADP+, NAD+ and NADPH
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additional information
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not affected by ATP, AMP, citrate, pyruvate, and malate
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additional information
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no inhibition by glucose, glucose 1-phosphate, sucrose, D-fructose, glycolate, succinate, UDPglucose; no inhibition by pyruvate, malate
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additional information
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no effect of glucose, pyruvate, fructose 2,6-bisphosphate
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additional information
neither inhibitory nor activating: oxaloacetic acid, glucose 6-phosphate, citric acid, isocitric acid, 2,3-bisphosphoglyceric acid and malic acid at 5 mM
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