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2.7.2.1: acetate kinase

This is an abbreviated version!
For detailed information about acetate kinase, go to the full flat file.

Word Map on EC 2.7.2.1

Reaction

ATP
+
acetate
=
ADP
+
acetyl phosphate

Synonyms

acetate kinase (phosphorylating), acetic kinase, acetokinase, ACK, ackA, AckA1, AckA2, ACKase, AK, ATP-ecoAK, ATP-specific AK, EAK, EutP, EutQ, MM_0495, Sak, short chain fatty acid kinase, StAckA, urkinase

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.2 Phosphotransferases with a carboxy group as acceptor
                2.7.2.1 acetate kinase

Crystallization

Crystallization on EC 2.7.2.1 - acetate kinase

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
crystallized at 1.9 A using the hanging drop vapor diffusion method. Each active site is located at an interdomain interface, and the acetate and phosphate binding pockets display sequence and structural conservation with their prokaryotic counterparts
crystallized at 2.4 A using the hanging drop vapor diffusion method. Each active site is located at an interdomain interface, and the acetate and phosphate binding pockets display sequence and structural conservation with their prokaryotic counterparts
in presence of substrate and transition states analogues
space group C2, unit cell dimensions a = 181 A, b = 67 A, c = 83 A, beta 103 degrees
-
three-dimensional structure of Methanosarcina thermophila acetate kinase bound to ADP
hanging drop vapor diffusion method, using 0.2 M lithium sulfate monohydrate, 0.1 M Tris/HCl (pH 8.5), and 24% (w/v) PEG 3350
crystal structures of Salmonella typhimurium AckA unliganded (Form-I, 2.70 A resolution) and citrate-bound (Form-II, 1.90 A resolution) are reported. Unexpectedly, Form-II StAckA structure show a drastic change in the conformation of residues 230-300 compared to that of Form-I
crystallized in two different crystal forms using the microbatch-under-oil method. Structural differences between two crystal forms of StAckA are observed. Form I crystals diffract to 2.70 A resolution and form II crystals, diffract to a higher resolution of 2.35 A
-