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2.7.2.1: acetate kinase

This is an abbreviated version!
For detailed information about acetate kinase, go to the full flat file.

Word Map on EC 2.7.2.1

Reaction

ATP
+
acetate
=
ADP
+
acetyl phosphate

Synonyms

acetate kinase (phosphorylating), acetic kinase, acetokinase, ACK, ackA, AckA1, AckA2, ACKase, AK, ATP-ecoAK, ATP-specific AK, EAK, EutP, EutQ, MM_0495, Sak, short chain fatty acid kinase, StAckA, urkinase

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.2 Phosphotransferases with a carboxy group as acceptor
                2.7.2.1 acetate kinase

General Stability

General Stability on EC 2.7.2.1 - acetate kinase

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GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
all 4 substrates of the forward and reverse reaction protect the enzyme from inactivation by diethyldicarbonate
-
almost no decrease in activity after several freezing and thawing cycles
-
ATP and acetate protects against inactivation
-
ATP or ADP protects the enzyme from inactivation
-
ATP, ADP and AMP protects against inactivation by N-ethylmaleimide
-
destroyed by repeated freezing and thawing
stabilized against heat inactivation by salts, most effective (NH4)2SO4
-
stabilized during storage by L-cysteine
-
the enzyme is unaffected by repeated freezing and thawing
unaffected by repeated freezing and thawing
-