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2.7.2.10: phosphoglycerate kinase (GTP)

This is an abbreviated version!
For detailed information about phosphoglycerate kinase (GTP), go to the full flat file.

Reaction

GTP
+
3-phospho-D-glycerate
=
GDP
 +
3-phospho-D-glyceroyl phosphate

Synonyms

3-phosphoglycerate kinase, kinase (phosphorylating), phosphoglycerate (guanosine triphosphate), kinase, phosphoglycerate (phosphorylating guanosine triphosphate), PGK

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.2 Phosphotransferases with a carboxy group as acceptor
                2.7.2.10 phosphoglycerate kinase (GTP)

Substrates Products

Substrates Products on EC 2.7.2.10 - phosphoglycerate kinase (GTP)

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + 3-phospho-D-glycerate
ADP + 3-phospho-D-glyceroyl 1-phosphate
show the reaction diagram
-
in glycolytic direction selectivity for GDP over ADP is 150-fold, selectivity for GTP over ATP is about 50fold
-
-
r
GDP + 3-phospho-D-glyceroyl 1-phosphate
GTP + 3-phospho-D-glycerate
show the reaction diagram
GTP + 3-phospho-D-glycerate
GDP + 3-phospho-D-glyceroyl 1-phosphate
show the reaction diagram
GTP + 3-phospho-D-glycerate
GDP + 3-phospho-D-glyceroyl phosphate
show the reaction diagram
-
-
-
-
?
ITP + 3-phospho-D-glycerate
IDP + 3-phospho-D-glyceroyl 1-phosphate
show the reaction diagram
-
in glycolytic direction 40% of the activity with GDP, 30% of the activity with GTP
-
-
r