2.7.2.12: acetate kinase (diphosphate)
This is an abbreviated version!
For detailed information about acetate kinase (diphosphate), go to the full flat file.
Reaction
Synonyms
acetate kinase (PPi), acetate kinase (PPi-forming), ACK, diphosphate-specific AK, EhACK, phosphotransferase, pyrophosphate-acetate, PPi-dependent AK, PPi-ehiAK, PPi-forming acetate kinase, pyrophosphate-acetate phosphotransferase, pyrophosphate-dependent AK, pyrophosphate:acetate phosphotransferase
ECTree
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Substrates Products on EC 2.7.2.12 - acetate kinase (diphosphate)
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
phosphate + acetyl phosphate
diphosphate + acetate
-
much greater activity in the direction of acetate formation
-
r
phosphate + acetyl phosphate
diphosphate + acetate
-
much greater activity in the direction of acetate formation
-
r
additional information
?
-
-
no activity with ADP, GDP, UDP, IDP or CDP
-
-
?
additional information
?
-
-
unlike other characterized ACKs, EhACK shows only diphosphate-dependent activity in the direction of acetyl phosphate formation. ATP does not serve as a phosphoryl donor
-
-
?
additional information
?
-
D-glucose 6-phosphate, D-fructose 6-phosphate, D-fructose 1,6-bisphophate, ADP, ATP and AMP used at the physiological concentrations and 1 mM each of 3-phosphoglycerate, 2-phosphoglycerate, phosphoenolpyruvate, UDP-glucose, UTP, O-phosphoserine and phosphocreatine are no substrates for the enzyme. The enzyme has no activity in the acetyl phosphate-forming direction
-
-
-
additional information
?
-
-
D-glucose 6-phosphate, D-fructose 6-phosphate, D-fructose 1,6-bisphophate, ADP, ATP and AMP used at the physiological concentrations and 1 mM each of 3-phosphoglycerate, 2-phosphoglycerate, phosphoenolpyruvate, UDP-glucose, UTP, O-phosphoserine and phosphocreatine are no substrates for the enzyme. The enzyme has no activity in the acetyl phosphate-forming direction
-
-
-
additional information
?
-
-
no activity with ADP, GDP, UDP, IDP or CDP
-
-
?
