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2.7.4.12: T2-induced deoxynucleotide kinase

This is an abbreviated version!
For detailed information about T2-induced deoxynucleotide kinase, go to the full flat file.

Word Map on EC 2.7.4.12

Reaction

ATP
+
dGMP (or dTMP)
=
ADP
+
dGDP (or dTDP)

Synonyms

deoxynucleotide kinase, kinase, deoxynucleotide (phosphorylating, T2-induced)

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.4 Phosphotransferases with a phosphate group as acceptor
                2.7.4.12 T2-induced deoxynucleotide kinase

Substrates Products

Substrates Products on EC 2.7.4.12 - T2-induced deoxynucleotide kinase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + 5-hydroxymethyl-dCMP
ADP + 5-hydroxymethyl-dCDP
show the reaction diagram
-
phosphorylation at about half the rate of dGMP or dTMP
-
r
ATP + dGMP
ADP + dGDP
show the reaction diagram
ATP + dTMP
ADP + dTDP
show the reaction diagram
-
as good as dGMP
-
r
dATP + dGMP
dADP + dGDP
show the reaction diagram
-
phosphorylation at about 80-90% the rate of ATP
-
-
r
dATP + dTMP
dADP + dTDP
show the reaction diagram
-
phosphorylation at about 80-90% the rate of ATP
-
-
r
additional information
?
-
-
poor substrates are dUMP or 5-methyl-dCMP, no donor substrates are GTP, CTP, dGTP, dCTP, or dTTP, no acceptor substrates are dCMP, dAMP, GMP, or UMP
-
-
?