2.7.4.14: UMP/CMP kinase

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For detailed information about UMP/CMP kinase, go to the full flat file.

Word Map on EC 2.7.4.14

2.7.4.14

dcmp

deoxycytidine

gemcitabine

cidofovir

nmp-binding

umpks

medicine

diagnostics

Reaction

Synonyms

ATP:UMP-CMP phosphotransferase, CMP kinase, CMP/UMP kinase, CMPK, CMPK1, CMPK2, CTP:CMP phosphotransferase, cytidine monophosphate kinase, cytidine/uridine monophosphate kinase 2, cytidylate kinase, dCK, deoxycytidine kinase, EC 2.7.4.5, kinase, cytidylate (phosphorylating), More, MssA protein, nucleoside monophosphate kinase, P25, pyrimidine nucleoside monophosphate kinase, UCK, UMP-CMP kinase, UMP-CMP kinase 2, UMP-CMPK2, UMP/CMP kinase, UMP/CMP kinase 1, UMP/CMPK1, UMPK, uridine monophosphate/cytidine monophosphate kinase

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.4 Phosphotransferases with a phosphate group as acceptor

2.7.4.14 UMP/CMP kinase

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Results	in table
13	Activating Compound
3225	AA Sequence
3	Application
1	CAS Registry Number
12	Cloned(Commentary)
7	Cofactor
1	Crystallization (Commentary)
112	Disease/ Diagnostics
1	Expression
9	General Information
8	General Stability
6	IC50 Value
45	Inhibitors
11	kcat/KM [mM/s]
10	Ki Value [mM]
132	KM Value [mM]
10	Localization
21	Metals/Ions
7	Molecular Weight [Da]
28	Natural Substrates/ Products (Substrates)
215	Organism
8	Pathway
29	PDB ID
7	pH Optimum
2	pH Range
3	pH Stability
1	pI Value
15	Protein Variants
13	Purification (Commentary)
6	Reaction
3	Reaction Type
40	Reference
1	Renatured (Commentary)
55	Source Tissue
9	Specific Activity [micromol/min/mg]
6	Storage Stability
188	Substrates and Products (Substrate)
6	Subunits
50	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
12	Temperature Stability [°C]
30	Turnover Number [1/s]

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diagnostics

Homo sapiens

P30085

UMP-CMP kinase (CMPK1) as a prognostic marker for triple negative breast cancer. Analysis of 461 breast adenocarcinoma samples, overview. While cytoplasmic CMPK1 does not show any association to metastasis free survival (MFS), nuclear CMPK1 is associated to poor prognosis independently from other prognostic factors in stratified Cox regression analyses

739700

medicine

2 entries