2.7.4.14: UMP/CMP kinase

This is an abbreviated version!
For detailed information about UMP/CMP kinase, go to the full flat file.

Reaction

Synonyms

ATP:UMP-CMP phosphotransferase, CMP kinase, CMP/UMP kinase, CMPK, CMPK1, CMPK2, CTP:CMP phosphotransferase, cytidine monophosphate kinase, cytidine/uridine monophosphate kinase 2, cytidylate kinase, dCK, deoxycytidine kinase, EC 2.7.4.5, kinase, cytidylate (phosphorylating), More, MssA protein, nucleoside monophosphate kinase, P25, pyrimidine nucleoside monophosphate kinase, UCK, UMP-CMP kinase, UMP-CMP kinase 2, UMP-CMPK2, UMP/CMP kinase, UMP/CMP kinase 1, UMP/CMPK1, UMPK, uridine monophosphate/cytidine monophosphate kinase

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.4 Phosphotransferases with a phosphate group as acceptor

                2.7.4.14 UMP/CMP kinase

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Results	in table
13	Activating Compound
3225	AA Sequence
3	Application
1	CAS Registry Number
12	Cloned(Commentary)
7	Cofactor
1	Crystallization (Commentary)
112	Disease/ Diagnostics
1	Expression
9	General Information
8	General Stability
6	IC50 Value
45	Inhibitors
11	kcat/KM [mM/s]
10	Ki Value [mM]
132	KM Value [mM]
10	Localization
21	Metals/Ions
7	Molecular Weight [Da]
28	Natural Substrates/ Products (Substrates)
215	Organism
8	Pathway
29	PDB ID
7	pH Optimum
2	pH Range
3	pH Stability
1	pI Value
15	Protein Variants
13	Purification (Commentary)
6	Reaction
3	Reaction Type
40	Reference
1	Renatured (Commentary)
55	Source Tissue
9	Specific Activity [micromol/min/mg]
6	Storage Stability
188	Substrates and Products (Substrate)
6	Subunits
50	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
12	Temperature Stability [°C]
30	Turnover Number [1/s]

Storage Stability

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Storage Stability on EC 2.7.4.14 - UMP/CMP kinase

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STORAGE STABILITY

ORGANISM

UNIPROT

LITERATURE

-10°C, 30% loss of activity within 2 months

Escherichia coli

-

645138

-20°C, concentrated enzyme solution in 30% glycerol, less than 5% loss of activity per month

Homo sapiens

-

645141

-20°C, in 25 mM Tris-acetate buffer, pH 7.5, 50 mM 2-mercaptoethanol, 50% glycerol, stable for at least 2 months

Rattus norvegicus

-

645139

-80°C, up to 12 months

Rattus norvegicus

-

645147

4°C, 0.2 mg/ml, 2 weeks, 20% loss of activity

Tetrahymena pyriformis

-

645137

4°C, considerable loss of activity within 24 h, DTT stabilizes, more stable in 20 mM phosphate buffer, pH 8 than in Tris-HCl buffer

Rattus norvegicus

-

645147