2.7.4.2: phosphomevalonate kinase

This is an abbreviated version!
For detailed information about phosphomevalonate kinase, go to the full flat file.

Word Map on EC 2.7.4.2

2.7.4.2

isopentenyl

isoprenoids

diphosphomevalonate

5-diphosphate

mevalonate-5-pyrophosphate

pyrophosphomevalonate

2.7.1.36

cholesterogenesis

zellweger

nonsterol

medicine

Reaction

Synonyms

5-phosphomevalonate kinase, ATP:5-phosphomevalonate phosphotransferase, CcPMK, ERG8, GbPMK, kinase, phosphomevalonate (phosphorylating), mevalonate phosphate kinase, mevalonate-5-phosphate kinase, mevalonic acid phosphate kinase, More, phosphomevalonate kinase, phosphomevalonic kinase, PMK, PMVAK, PMVK, SSO2988

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.4 Phosphotransferases with a phosphate group as acceptor

2.7.4.2 phosphomevalonate kinase

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Results	in table
1	Activating Compound
6036	AA Sequence
2	Application
1	CAS Registry Number
18	Cloned(Commentary)
8	Cofactor
5	Crystallization (Commentary)
12	Disease/ Diagnostics
2	Expression
16	General Information
1	General Stability
29	Inhibitors
14	Ki Value [mM]
131	KM Value [mM]
7	Localization
41	Metals/Ions
16	Molecular Weight [Da]
23	Natural Substrates/ Products (Substrates)
42	Organism
1	Oxidation Stability
7	Pathway
8	PDB ID
9	pH Optimum
3	pH Range
1	pH Stability
2	pI Value
30	Protein Variants
16	Purification (Commentary)
7	Reaction
4	Reaction Type
41	Reference
26	Source Tissue
7	Specific Activity [micromol/min/mg]
6	Storage Stability
63	Substrates and Products (Substrate)
16	Subunits
44	Synonyms
1	Systematic Name
9	Temperature Optimum [°C]
2	Temperature Stability [°C]
4	Turnover Number [1/s]

Purification

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Purification on EC 2.7.4.2 - phosphomevalonate kinase

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2 entries

ammonium sulfate, DEAE-cellulose, BioGel P-150, hydroxylapatite, Blue Dextran-Sepharose

Sus scrofa

645174, 645177

ammonium sulfate, ethanol, phosphate gel, DEAE-cellulose

Saccharomyces cerevisiae

645173

native enzyme from liver

Sus scrofa

671609

Ni-NTA resin column chromatography

Saccharomyces cerevisiae

P24521

739502

Ni-Sepharose column chromatography

Homo sapiens

Q15126

721510

Q Sepharose, Phenyl Sepharose, Sephacryl S200, Mono Q, gel filtration, Shodex KW803

Catharanthus roseus

645180

recombinant His-tagged enzyme from Escherichia coli strain BL21 by nickel affinity chromatography

Saccharomyces cerevisiae

P24521

758668

recombinant His-tagged wild-type and mutant enzymes from Escherichia coli by nickel affinity chromatography

2 entries

recombinant His6-tagged enzyme from Escherichia coli strain BL21(DE3) by nickel affinity chromatography and gel filtration

Homo sapiens

710506

recombinant protein

Enterococcus faecalis

663336

Se-Met fusion protein, glutathione and Sepharose Q resins

Streptococcus pneumoniae

645182

Sephadex G-200

Hevea brasiliensis

645176