2.7.4.25: (d)CMP kinase
This is an abbreviated version!
For detailed information about (d)CMP kinase, go to the full flat file.
Word Map on EC 2.7.4.25
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2.7.4.25
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beet
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bnyvv
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rhizomania
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resistance-breaking
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roscovitine
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polymyxa
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2.7.4.14
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tetragonia
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expansa
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biotechnology
- 2.7.4.25
- beet
- bnyvv
-
rhizomania
-
resistance-breaking
- roscovitine
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polymyxa
-
2.7.4.14
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tetragonia
- expansa
- biotechnology
Reaction
Synonyms
ATP:CMP phosphotransferase, bacterial cytidylate kinase, CMK, CMP kinase, CMPK, cytidine 5’-monophosphate kinase, cytidine monophosphate kinase, cytidylate kinase, dCMP kinase, deoxycytidine monophosphate kinase, deoxycytidine monophosphokinase, deoxycytidylate kinase, More, P25 protein, prokaryotic cytidylate kinase, SP1603, UCK, UMP-CMP kinase
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Natural Substrates Products
Natural Substrates Products on EC 2.7.4.25 - (d)CMP kinase
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REACTION DIAGRAM
additional information
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bacterial CMP kinases are specific for CMP and dCMP, whereas the related eukaryotic NMP kinase phosphorylates CMP and UMP with similar efficiency. Bacterial CMP kinase has a narrower NMP-binding pocket and a hydrogen-bonding network involving the pyrimidine moiety specific for the cytosine nucleobase compared to eukaryotic UMP?CMP kinases
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ATP + dCMP
ADP + dCDP
Escherichia coli CMPK phosphorylates dCMP nearly as well as it does CMP
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