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2.7.4.26: isopentenyl phosphate kinase

This is an abbreviated version!
For detailed information about isopentenyl phosphate kinase, go to the full flat file.

Word Map on EC 2.7.4.26

Reaction

ATP
+
isopentenyl phosphate
=
ADP
+
isopentenyl diphosphate

Synonyms

HvIpk, HVO_2762, IPK, Ipk2, isopentenyl phosphate kinase, MJ0044, MM_1763, Ta0103

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.4 Phosphotransferases with a phosphate group as acceptor
                2.7.4.26 isopentenyl phosphate kinase

Crystallization

Crystallization on EC 2.7.4.26 - isopentenyl phosphate kinase

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
X-ray structure determination
catalytically competent structure in complex with Mg2+ . Substrate binding results in significant conformational change of residues Lys204, Glu207, and Lys211 located on the alphaG helix to form a strong salt bridge network with Asp145, which in turn tethers the invariant Ser142 via H-bond interaction. The conformational change shuts the subtrate entrance channel formed between the alphaG and alphaE helices
X-ray structure determination