Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.7.4.3: adenylate kinase

This is an abbreviated version!
For detailed information about adenylate kinase, go to the full flat file.

Word Map on EC 2.7.4.3

Reaction

ATP
+
AMP
=
2 ADP

Synonyms

5'-AMP-kinase, ABC adenylate kinase, AD-004 like protein, adenosine 5'-triphosphate:adenosine 5'-monophosphate phosphotransferase, adenylate kinase, adenylate kinase 1, adenylate kinase 2, adenylate kinase 4, adenylate kinase 5, adenylate kinase 6, adenylate kinase 9, adenylate kinase isoenzyme 1, adenylate kinase isozyme 2, adenylate kinase-2, adenylate kinase-like protein 1, adenylic kinase, adenylokinase, ADK, ADK1, ADK2, ADLP, AK1, AK2, AK4, AK5, AK5p1, AK5p2, AK6, AK7, AK8, AK9, AKE, AKlse4, AKm, AKmeso, AKp, AKpsycrho, AKthermo, ATP:AMP phosphotransferase, CFTR, CINAP, coilin interacting nuclear ATPase protein, cystic fibrosis transmembrane conductance regulator, DAK2, Dak6, kinase, adenylate (phosphorylating), kinase, myo- (phosphorylating), MeADK1, MeADK2, MJ0458, myokinase, nonstructural protein 4B, NS4B, pfSMCnbd, phosphotransferase, Rv0733, Saci_0573, SpAdK, structural maintenance of chromosome protein

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.4 Phosphotransferases with a phosphate group as acceptor
                2.7.4.3 adenylate kinase

Specific Activity

Specific Activity on EC 2.7.4.3 - adenylate kinase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.011
mutant enzyme CINAP H79G, in 100 mM Tris-HCl, pH 7.5, 60 mM KCl, temperature not specified in the publication
0.018
wild type enzyme CINAP, in 100 mM Tris-HCl, pH 7.5, 60 mM KCl, temperature not specified in the publication
0.6
nucleotide-binding domain 2 of wild type, with ATP
0.9
wild type, with AMP
1.2
wild type, with ATP
1.4
wild type, with ADP
10
Q14EL6
recombinant enzyme, in 110 mM TEA-HCl, pH 7.6, at 25°C
100
Q7Z0H0
wild type AK
1062
-
liver, mitochondria
129
-
mutant S129F
14
substrate: ATP, pH and temperature not specified in the publication
1400 - 1600
-
muscle, 30°C, pH 8.1
1450
-
30°C, pH 7.4
1480
-
allelozyme AK1*1
1550
-
-
1560
Megalodesulfovibrio gigas
-
apoenzyme, pH 7.4, 30°C
1600 - 1700
1640
-
ATP formation, pH 7.4, 30°C
1700 - 1800
-
muscle, 30°C, pH 8.1
1810
-
muscle
1980
Megalodesulfovibrio gigas
-
fully zinc-substitued form, pH 7.4, 30°C
2000
wild-type, 37°C
2020
Megalodesulfovibrio gigas
-
native form, pH 7.4, 30°C
2170
Megalodesulfovibrio gigas
-
fully cobalt-substitued form, pH 7.4, 30°C
2244
-
muscle, pH 8.0, 30°C
225 - 250
-
liver, 30°C, pH 8.1
230
-
liver, pH 8.0, 30°C
250
-
mutant P87S
280
-
30°C, pH 7.4
32
-
pH 8.7, 25°C, ATP production
350 - 400
-
-
420
-
allelozyme AK1*2
56
substrate: ATP, pH and temperature not specified in the publication
60
-
isozyme II
76.7 - 79.3
81
substrate: ATP, pH and temperature not specified in the publication
89
substrate: ATP, pH and temperature not specified in the publication
additional information