2.7.4.9: dTMP kinase

This is an abbreviated version!
For detailed information about dTMP kinase, go to the full flat file.

Word Map on EC 2.7.4.9

2.7.4.9

tuberculosis

nucleoside

deoxycytidine

dtdp

aztmp

medicine

drug development

Reaction

Synonyms

ATP: TMP phosphotransferase, Cdc8, deoxythymidine 5'-monophosphate kinase, deoxythymidine monophosphate kinase, dTMP kinase, dTMP kinases, dTMPK, human thymidine monophosphate kinase (hTMPK), kinase, thymidine monophosphate (phosphorylating), kinase, thymidylate (phosphorylating), ORF454, PfTMK, S. aureus thymidylate kinase, thymidine 5'-monophosphate kinase, thymidine kinase, thymidine monophosphate kinase, thymidylate kinase, thymidylate monophosphate kinase, thymidylic acid kinase, thymidylic kinase, TK1, TMK, TMP kinase, TMPK, TMPKmt, TTHA1607, TYMK

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.4 Phosphotransferases with a phosphate group as acceptor

2.7.4.9 dTMP kinase

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Results	in table
1	Activating Compound
45422	AA Sequence
12	Application
1	CAS Registry Number
29	Cloned(Commentary)
9	Cofactor
23	Crystallization (Commentary)
179	Disease/ Diagnostics
23	General Information
8	General Stability
178	IC50 Value
502	Inhibitors
18	kcat/KM [mM/s]
198	Ki Value [mM]
101	KM Value [mM]
15	Localization
29	Metals/Ions
21	Molecular Weight [Da]
29	Natural Substrates/ Products (Substrates)
298	Organism
11	Pathway
232	PDB ID
9	pH Optimum
6	pH Range
3	pH Stability
29	Protein Variants
27	Purification (Commentary)
3	Reaction
4	Reaction Type
107	Reference
1	Renatured (Commentary)
23	Source Tissue
11	Specific Activity [micromol/min/mg]
4	Storage Stability
215	Substrates and Products (Substrate)
21	Subunits
99	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Range [°C]
14	Temperature Stability [°C]
63	Turnover Number [1/s]

Cloned

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Cloned on EC 2.7.4.9 - dTMP kinase

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5 entries

expressed as His-tag fusion protein in Escherichia coli BL21(DE3)

Homo sapiens

661477

expressed in Escherichia coli

4 entries

expressed in Escherichia coli BL21(DE3) cells

2 entries

expressed in Escherichia coli JM109 cells

Homo sapiens

701680

expressed in Escherichia coli Rosetta Oxford cells

Ehrlichia chaffeensis

Q2GHN3

721198

expressed in Mus musculus heart

Homo sapiens

705442

expression as fusion protein with Green Fluorescent Protein in HeLa cell

Homo sapiens

692491

expression in Escherichia coli

8 entries

expression of wild-type enzyme and G146A variant in Escherichia coli BL21(DE3)/pDIA17

Escherichia coli

645202

full length and truncated enzyme lacking the first 22 amino acids expressed in Escherichia coli BL21 C41 (DE3)

Equid alphaherpesvirus 4

663399

histidine-tagged enzyme, overexpression in Escherichia coli

Streptococcus pneumoniae

645203

overexpression in Escherichia coli

Mycobacterium tuberculosis

645207