2.7.6.1: ribose-phosphate diphosphokinase
This is an abbreviated version!
For detailed information about ribose-phosphate diphosphokinase, go to the full flat file.
Word Map on EC 2.7.6.1
-
2.7.6.1
-
purine
-
erythrocyte
-
superactivity
-
pyrimidine
-
x-linked
-
phosphoribosyltransferase
-
uric
-
gout
-
hypoxanthine
-
hypoxanthine-guanine
-
deafness
-
charcot-marie-tooth
-
sensorineural
-
hemolysates
-
diphosphorylated
-
nonsyndromic
-
hgprt
-
hyperuricaemia
-
lesch-nyhan
-
phosphoribosyl-pyrophosphate
-
feedback-resistant
-
synthesis
-
medicine
- 2.7.6.1
- purine
- erythrocyte
-
superactivity
- pyrimidine
-
x-linked
- phosphoribosyltransferase
-
uric
- gout
- hypoxanthine
-
hypoxanthine-guanine
- deafness
- charcot-marie-tooth
-
sensorineural
-
hemolysates
-
diphosphorylated
-
nonsyndromic
- hgprt
-
hyperuricaemia
- lesch-nyhan
-
phosphoribosyl-pyrophosphate
-
feedback-resistant
- synthesis
- medicine
Reaction
Synonyms
5-phospho-alpha D-ribosyl 1-diphosphate synthase, 5-phosphoribose pyrophosphorylase, 5-phosphoribosyl-1-alpha-diphosphate synthase, 5-phosphoribosyl-1-pyrophosphate synthetase, 5-phosphoribosyl-alpha-1-pyrophosphate synthetase, AN6711.2, ATP: D-ribose-5-phosphate pyrophosphotransferase, ATP:D-ribose-5-phosphate pyrophosphotransferase, bsPRS, Pcal_1127, phosphoribosyl diphosphate synthase, phosphoribosyl pyrophosphate synthase 1 (PRS-1), phosphoribosyl pyrophosphate synthase enzyme, phosphoribosyl pyrophosphate synthetase, phosphoribosyl-1-pyrophosphate synthetase, phosphoribosyl-diphosphate synthetase, phosphoribosylpyrophosphate synthase, phosphoribosylpyrophosphate synthetase, phosphoribosylpyrophosphate synthetase 1, phosphoribosylpyrophosphate synthetase subunit 1, PP-ribose P synthetase, PPRibP synthetase, PRibPP synthase, PRPP synthase, PRPP synthetase, PRPPase, PRPPS, PRPPS1, PRPPS2, PRPS1, Prps1a, Prps1b, PRS, PRS-I, PRS1, Prs4, PrsA, PrsB, PrsC, pyrophosphokinase, ribose phosphate, pyrophosphoribosylphosphate synthetase, ribophosphate pyrophosphokinase, ribose-5-phosphate pyrophosphokinase, ribose-phosphate pyrophosphokinase, ribose-phosphate pyrophosphokinase 1, RPPK, SSO1045, TT_C1184, TT_C1274
ECTree
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Reference on EC 2.7.6.1 - ribose-phosphate diphosphokinase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Kian, I.A.; Etingof, R.N.
Purine biosynthesis de novo in bovine retina: purification and characterization of amidophosphoribosyl transferase and phosphoribosyl pyrophosphate synthetase
Biochemistry
64
648-651
1999
Bos taurus
Switzer, R.L.
Regulation and mechanism of phosphoribosylpyrophosphate synthetase. I. Purification and properties of the enzyme from Salmonella typhimurium
J. Biol. Chem.
244
2854-2863
1969
Salmonella enterica subsp. enterica serovar Typhimurium
Ashihara, H.
Characterization of phosphoribosylpyrophosphate synthetase from spinach leaves
Z. Pflanzenphysiol.
83
379-392
1977
Spinacia oleracea
-
Switzer, R.L.
Phosphoribosylpyrophosphate synthetase and related pyrophosphokinases
The Enzymes,3rd Ed. (Boyer,P. D. ,ed. )
10
607-629
1974
Columba sp., Escherichia coli, Gallus gallus, Homo sapiens, Mus musculus, Ophiodon elongatus, Rattus norvegicus, Salmonella enterica subsp. enterica serovar Typhimurium
-
Switzer, R.L.; Gibson, K.J.
Phosphoribosylpyrophosphate synthetase (ribose-5-phosphate pyrophosphokinase) from Salmonella typhimurium
Methods Enzymol.
51
3-11
1978
Salmonella enterica subsp. enterica serovar Typhimurium, Salmonella enterica subsp. enterica serovar Typhimurium Su 422
Roth, D.G.; White, C.; Deuel, T.F.
Ribosephosphate pyrophosphokinase (rat liver)
Methods Enzymol.
51
12-17
1978
Rattus norvegicus
Arnvig, K.; Hove-Jensen, B.; Switzer, R.L.
Purification and properties of phosphoribosyl-diphosphate synthetase from Bacillus subtilis
Eur. J. Biochem.
192
195-200
1990
Bacillus subtilis
Schubert, K.R.; Switzer, R.L.; Shelton, E.
Studies of the quaternary structure and the chemical properties of phosphoribosylpyrophosphate synthetase from Salmonella typhimurium
J. Biol. Chem.
250
7492-7500
1975
Salmonella enterica subsp. enterica serovar Typhimurium, Salmonella enterica subsp. enterica serovar Typhimurium Su 422
Ishijima, S.; Kita, K.; Ahmad, I.; Ishizuka, T.; Taira, M.; Tatibana, M.
Expression of rat phosphoribosylpyrophosphate synthetase subunits I and II in Escherichia coli. Isolation and characterization of the recombinant isoforms
J. Biol. Chem.
266
15693-15697
1991
Rattus norvegicus
Roth, D.G.; Shelton, E.; Deuel, T.F.
Purification and properties of phosphoribosyl pyrophosphate synthetase from rat liver
J. Biol. Chem.
249
291-296
1974
Rattus norvegicus
Fox, I.H.; Kelley, W.N.
Human phosphoribosylpyrophosphate synthetase. Kinetic mechanism and end product inhibition
J. Biol. Chem.
247
2126-2131
1972
Homo sapiens
Switzer, R.L.; Sogin, D.C.
Regulation and mechanism of phosphoribosylpyrophosphate synthetase. V. Inhibition by end products and regulation by adenosine diphosphate
J. Biol. Chem.
248
1063-1073
1973
Salmonella enterica subsp. enterica serovar Typhimurium
Nosal, J.M.; Switzer, R.L.; Becker, M.A.
Overexpression, purification, and characterization of recombinant human 5-phosphoribosyl-1-pyrophosphate synthetase isozymes I and II
J. Biol. Chem.
268
10168-10175
1993
Homo sapiens
Becker, M.A.; Kostel, P.J.; Meyer, L.J.
Human phosphoribosylpyrophosphate synthetase. Comparison of purified normal and mutant enzymes
J. Biol. Chem.
250
6822-6830
1975
Homo sapiens
Kita, K.; Otsuki, T.; Ishizuka, T.; Tatibana, M.
Rat liver phosphoribosyl pyrophosphate synthetase: existence of the purified enzyme as heterogeneous aggregates and identification of the catalytic subunit
J. Biochem.
105
736-741
1989
Rattus norvegicus
Green, C.D.; Martin, D.W.
Characterization of a feedback-resistant phosphoribosylpyrophosphate synthetase from cultured, mutagenized hepatoma cells that overproduce purines
Proc. Natl. Acad. Sci. USA
70
3698-3702
1973
Rattus norvegicus
Parry, R.J.; Burns, M.R.; Skae, P.N.; Hoyt, J.C.; Pal, B.
Carbocyclic analogues of D-ribose-5-phosphate: synthesis and behavior with 5-phosphoribosyl alpha-1-pyrophosphate synthetases
Bioorg. Med. Chem.
4
1077-1088
1996
Bacillus subtilis, Homo sapiens, Salmonella enterica subsp. enterica serovar Typhimurium
Balzarini, J.; Nave, J.F.; Becker, M.A.; Tatibana, M.; De Clercq, E.
Kinetic properties of adenine nucleotide analogs against purified 5-phosphoribosyl-1-pyrophosphate synthetase from E. coli, rat liver and human erythrocytes
Nucleosides Nucleotides
14
1861-1871
1995
Escherichia coli, Homo sapiens, Rattus norvegicus
-
Okada, N.N.; Ishizuka, T.; Isogai, E.; Suzuki, N.; Tatibana, M.
Variation of phosphoribosylpyrophosphate synthetase activity in human cells
Biochem. Mol. Biol. Int.
44
1059-1067
1998
Homo sapiens
-
Sonoda, T.; Kita, K.; Ishijima, S.; Ishizuka, T.; Ahmad, I.; Tatibana, M.
Kinetic and regulatory properties of rat liver phosphoribosylpyrophosphate synthetase complex are partly distinct from those of isolated recombinant component catalytic subunits
J. Biochem.
122
635-640
1997
Rattus norvegicus
Eriksen, T.A.; Kadziola, A.; Larsen, S.
Binding of cations in Bacillus subtilis phosphoribosyldiphosphate synthetase and their role in catalysis
Protein Sci.
11
271-279
2002
Bacillus subtilis
Ishijima, S.; Asai, T.; Kita, K.; Sonoda, T.; Tatibana, M.
Partial reconstitution of mammalian phosphoribosylpyrophosphate synthetase in Escherichia coli cells. Coexpression of catalytic subunits with the 39-kDa associated protein leads to formation of soluble multimeric complexes of various compositions
Biochim. Biophys. Acta
1342
28-36
1997
Rattus norvegicus
Krath, B.N.; Hove-Jensen, B.
Implications of secondary structure prediction and amino acid sequence comparison of class I and class II phosphoribosyl diphosphate synthases on catalysis, regulation, and quaternary structure
Protein Sci.
10
2317-2324
2001
Spinacia oleracea
Becker, M.A.
Phosphoribosylpyrophosphate synthetase and the regulation of phosphoribosylpyrophosphate production in human cells
Prog. Nucleic Acid Res. Mol. Biol.
69
115-148
2001
Bacillus subtilis, Homo sapiens
Tatibana, M.; Kita, K.; Taira, M.; Ishijima, S.; Sonoda, T.; Ishizuka, T.; Iizasa, T.; Ahmad, I.
Mammalian phosphoribosyl-pyrophosphate synthetase
Adv. Enzyme Regul.
35
229-249
1995
Homo sapiens, Rattus norvegicus
Willemoes, M.; Hove-Jensen, B.
Binding of divalent magnesium by Escherichia coli phosphoribosyl diphosphate synthetase
Biochemistry
36
5078-5083
1997
Escherichia coli
Becker, M.A.; Taylor, W.; Smith, P.R.; Ahmed, M.
Overexpression of the normal phosphoribosylpyrophosphate synthetase 1 isoform underlies catalytic superactivity of human phosphoribosylpyrophosphate synthetase
J. Biol. Chem.
271
19894-19899
1996
Homo sapiens
Eriksen, T.A.; Kadziola, A.; Bentsen, A.K.; Harlow, K.W.; Larsen, S.
Structural basis for the function of Bacillus subtilis phosphoribosyl-pyrophosphate synthetase
Nat. Struct. Biol.
7
303-308
2000
Bacillus subtilis
Gallois, R.; Prevot, J.C.; Clement, A.; Jacob, J.L.
Purification and characterization of phosphoribosylpyrophosphate synthetase from rubber tree latex
Plant Physiol.
115
847-852
1997
Hevea brasiliensis
Krath, B.N.; Hove-Jensen, B.
Organellar and cytosolic localization of four phosphoribosyl diphosphate synthase isozymes in spinach
Plant Physiol.
119
497-506
1999
Spinacia oleracea
Willemoes, M.; Hove-Jensen, B.; Larsen, S.
Steady state kinetic model for the binding of substrates and allosteric effectors to Escherichia coli phosphoribosyl-diphosphate synthase
J. Biol. Chem.
275
35408-35412
2000
Escherichia coli
Krath, B.N.; Hove-Jensen, B.
Class II recombinant phosphoribosyl diphosphate synthase from spinach. Phosphate independence and diphosphoryl donor specificity
J. Biol. Chem.
276
17851-17856
2001
Spinacia oleracea
Jarori, G.K.; Murali, N.; Switzer, R.L.; Rao, B.D.N.
Conformation of MgATP bound to 5-phospho-a-D-ribose 1-diphosphate synthetase by two-dimensional transferred nuclear Overhauser effect spectroscopy
Eur. J. Biochem.
230
517-524
1995
Salmonella enterica subsp. enterica serovar Typhimurium
Bentsen, A.K.; Larsen, T.A.; Kadziola, A.; Larsen, S.; Harlow, K.W.
Overexpression of Bacillus subtilis phosphoribosylpyrophosphate synthetase and crystallization and preliminary X-ray characterization of the free enzyme and its substrate-effector complexes
Proteins
24
238-246
1996
Bacillus subtilis
Napolitano, H.B.; Sculaccio, S.A.; Thiemann, O.H.; Oliva, G.
Preliminary crystallographic analysis of sugar cane phosphoribosylpyrophosphate synthase
Acta Crystallogr. Sect. F
F61
49-51
2005
Saccharum officinarum
Kaida, A.; Ariumi, Y.; Baba, K.; Matsubae, M.; Takao, T.; Shimotohno, K.
Identification of a novel p300-specific-associating protein, PRS1 (phosphoribosylpyrophosphate synthetase subunit 1)
Biochem. J.
391
239-247
2005
Homo sapiens
Hove-Jensen, B.; McGuire, J.N.
Surface exposed amino acid differences between mesophilic and thermophilic phosphoribosyl diphosphate synthase
Eur. J. Biochem.
271
4526-4533
2004
[Bacillus] caldolyticus
Hove-Jensen, B.; Bentsen, A.K.; Harlow, K.W.
Catalytic residues Lys197 and Arg199 of Bacillus subtilis phosphoribosyl diphosphate synthase. Alanine-scanning mutagenesis of the flexible catalytic loop
FEBS J.
272
3631-3639
2005
Bacillus subtilis
Hove-Jensen, B.
Heterooligomeric phosphoribosyl diphosphate synthase of Saccharomyces cerevisiae: combinatorial expression of the five PRS genes in Escherichia coli
J. Biol. Chem.
279
40345-40350
2004
Saccharomyces cerevisiae
de Brouwer, A.P.; Williams, K.L.; Duley, J.A.; van Kuilenburg, A.B.; Nabuurs, S.B.; Egmont-Petersen, M.; Lugtenberg, D.; Zoetekouw, L.; Banning, M.J.; Roeffen, M.; Hamel, B.C.; Weaving, L.; Ouvrier, R.A.; Donald, J.A.; Wevers, R.A.; Christodoulou, J.; van Bokhoven, H.
Arts syndrome is caused by loss-of-function mutations in PRPS1
Am. J. Hum. Genet.
81
507-518
2007
Homo sapiens (P60891), Homo sapiens
Kim, H.J.; Sohn, K.M.; Shy, M.E.; Krajewski, K.M.; Hwang, M.; Park, J.H.; Jang, S.Y.; Won, H.H.; Choi, B.O.; Hong, S.H.; Kim, B.J.; Suh, Y.L.; Ki, C.S.; Lee, S.Y.; Kim, S.H.; Kim, J.W.
Mutations in PRPS1, which encodes the phosphoribosyl pyrophosphate synthetase enzyme critical for nucleotide biosynthesis, cause hereditary peripheral neuropathy with hearing loss and optic neuropathy (cmtx5)
Am. J. Hum. Genet.
81
552-558
2007
Homo sapiens, Homo sapiens (P60891)
Li, S.; Lu, Y.; Peng, B.; Ding, J.
Crystal structure of human phosphoribosylpyrophosphate synthetase 1 reveals a novel allosteric site
Biochem. J.
401
39-47
2007
Bacillus subtilis, Homo sapiens, Homo sapiens (P60891)
Jimenez, A.; Santos, M.A.; Revuelta, J.L.
Phosphoribosyl pyrophosphate synthetase activity affects growth and riboflavin production in Ashbya gossypii
BMC Biotechnol.
8
67
2008
Eremothecium gossypii
Koslowsky, S.; Riegler, H.; Bergmueller, E.; Zrenner, R.
Higher biomass accumulation by increasing phosphoribosylpyrophosphate synthetase activity in Arabidopsis thaliana and Nicotiana tabacum
Plant Biotechnol. J.
6
281-294
2008
Eremothecium gossypii
Moran, R.; Kuilenburg, A.B.; Duley, J.; Nabuurs, S.B.; Retno-Fitri, A.; Christodoulou, J.; Roelofsen, J.; Yntema, H.G.; Friedman, N.R.; van Bokhoven, H.; de Brouwer, A.P.
Phosphoribosylpyrophosphate synthetase superactivity and recurrent infections is caused by a p.Val142Leu mutation in PRS-I
Am. J. Med. Genet. A
158A
455-460
2012
Homo sapiens (P60891), Homo sapiens
Zakataeva, N.P.; Romanenkov, D.V.; Skripnikova, V.S.; Vitushkina, M.V.; Livshits, V.A.; Kivero, A.D.; Novikova, A.E.
Wild-type and feedback-resistant phosphoribosyl pyrophosphate synthetases from Bacillus amyloliquefaciens: purification, characterization, and application to increase purine nucleoside production
Appl. Microbiol. Biotechnol.
93
2023-2033
2012
Bacillus amyloliquefaciens (E7EAU9), Bacillus amyloliquefaciens, Bacillus amyloliquefaciens IAM 1523 (E7EAU9)
Alderwick, L.J.; Lloyd, G.S.; Lloyd, A.J.; Lovering, A.L.; Eggeling, L.; Besra, G.S.
Biochemical characterization of the Mycobacterium tuberculosis phosphoribosyl-1-pyrophosphate synthetase
Glycobiology
21
410-425
2011
Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv
Cherney, M.M.; Cherney, L.T.; Garen, C.R.; James, M.N.
The structures of Thermoplasma volcanium phosphoribosyl pyrophosphate synthetase bound to ribose-5-phosphate and ATP analogs
J. Mol. Biol.
413
844-856
2011
Thermoplasma volcanium (Q97CA5), Thermoplasma volcanium
Koenigsknecht, M.; Fenlon, L.; Downs, D.
Phosphoribosylpyrophosphate synthetase (PrsA) variants alter cellular pools of ribose 5-phosphate and influence thiamine synthesis in Salmonella enterica
Microbiology
156
950-959
2010
Salmonella enterica, Salmonella enterica DM10373
Zhong, G.; Wei, W.; Guan, Q.; Ma, Z.; Wei, H.; Xu, X.; Zhang, S.; Lu, L.
Phosphoribosyl pyrophosphate synthetase, as a suppressor of the sepH mutation in Aspergillus nidulans, is required for the proper timing of septation
Mol. Microbiol.
86
894-907
2012
Aspergillus nidulans, Aspergillus nidulans WJA01
Hong, S.; Zhou, D.; Chen, C.; Wang, W.; Lv, Y.; Ye, Y.; Zou, P.; Yv, J.; Chang, X.; Yv, X.; Shi, L.; Ma, L.; Sun, Y.; Zhang, D.; Shen, B.; Zhu, C.
Ribose-phosphate pyrophosphokinase 1 (PRPS1) associated with deltamethrin resistance in Culex pipiens pallens
Parasitol. Res.
112
847-854
2013
Culex pipiens (H9D1K2), Culex pipiens
Lucarelli, A.P.; Buroni, S.; Pasca, M.R.; Rizzi, M.; Cavagnino, A.; Valentini, G.; Riccardi, G.; Chiarelli, L.R.
Mycobacterium tuberculosis phosphoribosylpyrophosphate synthetase: biochemical features of a crucial enzyme for mycobacterial cell wall biosynthesis
PLoS ONE
5
e15494
2010
Mycobacterium tuberculosis, Mycobacterium tuberculosis Rv1017
Breda, A.; Martinelli, L.K.; Bizarro, C.V.; Rosado, L.A.; Borges, C.B.; Santos, D.S.; Basso, L.A.
Wild-type phosphoribosylpyrophosphate synthase (PRS) from Mycobacterium tuberculosis: a bacterial class II PRS?
PLoS ONE
7
e39245
2012
Mycobacterium tuberculosis, Mycobacterium tuberculosis Rv1017c
Kadziola, A.; Jepsen, C.H.; Johansson, E.; McGuire, J.; Larsen, S.; Hove-Jensen, B.
Novel class III phosphoribosyl diphosphate synthase: structure and properties of the tetrameric, phosphate-activated, non-allosterically inhibited enzyme from Methanocaldococcus jannaschii
J. Mol. Biol.
354
815-828
2005
Methanocaldococcus jannaschii (Q58761), Methanocaldococcus jannaschii, Methanocaldococcus jannaschii DSM 2661 (Q58761)
Andersen, R.W.; Leggio, L.L.; Hove-Jensen, B.; Kadziola, A.
Structure of dimeric, recombinant Sulfolobus solfataricus phosphoribosyl diphosphate synthase: a bent dimer defining the adenine specificity of the substrate ATP
Extremophiles
19
407-415
2015
Saccharolobus solfataricus (Q97Z86), Saccharolobus solfataricus, Saccharolobus solfataricus P2 (Q97Z86)
Timofeev, V.; Abramchik, Y.; Zhukhlistova, N.; Kuranova, I.
Crystallization and preliminary X-ray diffraction study of phosphoribosyl pyrophosphate synthetase from E. coli
Crystallogr. Rep.
60
685-688
2015
Escherichia coli (P0A717)
-
Bibi, T.; Perveen, S.; Aziz, I.; Bashir, Q.; Rashid, N.; Imanaka, T.; Akhtar, M.
Pcal_1127, a highly stable and efficient ribose-5-phosphate pyrophosphokinase from Pyrobaculum calidifontis
Extremophiles
20
821-830
2016
Pyrobaculum calidifontis (A3MV85), Pyrobaculum calidifontis, Pyrobaculum calidifontis JCM 11548 (A3MV85)
Timofeev, V.I.; Sinitsyna, E.V.; Kostromina, M.A.; Muravieva, T.I.; Makarov, D.A.; Mikheeva, O.O.; Kuranova, I.P.; Esipov, R.S.
Crystal structure of recombinant phosphoribosylpyrophosphate synthetase 2 from Thermus thermophilus HB27 complexed with ADP and sulfate ions
Acta Crystallogr. Sect. F
73
369-375
2017
Thermus thermophilus (Q5SHU3)
Zhou, W.; Tsai, A.; Dattmore, D.; Stives, D.; Chitrakar, I.; DAlessandro, A.; Patil, S.; Hicks, K.; French, J.
Crystal structure of E. coli PRPP synthetase
BMC Struct. Biol.
19
001
2019
Escherichia coli (P0A719), Escherichia coli
Timofeev, V.; Abramchik, Y.; Zhukhlistova, N.; Muravieva, T.; Esipov, R.; Kuranova, I.
Three-dimensional structure of phosphoribosyl pyrophosphate synthetase from E. coli at 2.71 A resolution
Crystallogr. Rep.
61
44-54
2016
Escherichia coli (P0A717)
-
Abramchik, Y.; Timofeev, V.; Muravieva, T.; Sinitsyna, E.; Esipov, R.; Kuranova, I.
Crystallization and preliminary X-ray diffraction analysis of recombinant phosphoribosylpyrophosphate synthetase from the thermophilic Thermus thermophilus strain HB27
Crystallogr. Rep.
62
78-81
2017
Thermus thermophilus (Q72I58)
-
Podshivalov, D.; Sidorov-Biryukov, D.; Timofeev, V.; Litunov, A.; Kostromina, M.; Sinitsyna, K.; Muravieva, T.; Kuranova, I.; Esipov, R.
Modeling of phosphoribosylpyrophosphate synthetase from Thermus thermophilus in complex with ATP and ribose 5-Phosphate
Crystallogr. Rep.
64
94-97
2019
Thermus thermophilus (Q5SHU3)
-
Yu, H.; Zhang, Y.; Zhang, D.; Lu, Y.; He, H.; Zheng, F.; Wang, M.
Identification of a ribose-phosphate pyrophosphokinase that can interact in vivo with the anaphase promoting complex/cyclosome
Int. J. Mol. Sci.
18
617
2017
Hevea brasiliensis
Jiang, P.; Wei, W.F.; Zhong, G.W.; Zhou, X.G.; Qiao, W.R.; Fisher, R.; Lu, L.
The function of the three phosphoribosyl pyrophosphate synthetase (Prs) genes in hyphal growth and conidiation in Aspergillus nidulans
Microbiology
163
218-232
2017
Aspergillus nidulans, Aspergillus nidulans (Q5AYB9), Aspergillus nidulans ATCC 38163, Aspergillus nidulans ATCC 38163 (Q5AYB9)
Delos Santos, K.; Kim, M.; Yergeau, C.; Jean, S.; Moon, N.S.
Pleiotropic role of Drosophila phosphoribosyl pyrophosphate synthetase in autophagy and lysosome homeostasis
PLoS Genet.
15
e1008376
2019
Drosophila melanogaster (Q9VT33)
Donini, S.; Garavaglia, S.; Ferraris, D.M.; Miggiano, R.; Mori, S.; Shibayama, K.; Rizzi, M.
Biochemical and structural investigations on phosphoribosylpyrophosphate synthetase from Mycobacterium smegmatis
PLoS ONE
12
e0175815
2017
Mycolicibacterium smegmatis (A0R3C8), Mycolicibacterium smegmatis, Mycolicibacterium smegmatis ATCC 700084 (A0R3C8)
Walter, B.M.; Szulc, A.; Glinkowska, M.K.
Reliable method for high quality His-tagged and untagged E. coli phosphoribosyl phosphate synthase (Prs) purification
Protein Expr. Purif.
169
105587
2020
Escherichia coli
Esipov, R.; Abramchik, Y.; Fateev, I.; Muravyova, T.; Artemova, K.; Konstantinova, I.; Kuranova, I.; Miroshnikov, A.
Recombinant phosphoribosyl pyrophosphate synthetases from Thermus thermophilus HB27 Isolation and properties
Russ. J. Bioorg. Chem.
42
512-521
2016
Thermus thermophilus (Q72I58), Thermus thermophilus (Q72IE8)
-
Pei, W.; Xu, L.; Varshney, G.K.; Carrington, B.; Bishop, K.; Jones, M.; Huang, S.C.; Idol, J.; Pretorius, P.R.; Beirl, A.; Schimmenti, L.A.; Kindt, K.S.; Sood, R.; Burgess, S.M.
Additive reductions in zebrafish PRPS1 activity result in a spectrum of deficiencies modeling several human PRPS1-associated diseases
Sci. Rep.
6
29946
2016
Danio rerio (Q08CA5), Danio rerio (Q4KME9), Danio rerio
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