2.7.6.4: nucleotide diphosphokinase
This is an abbreviated version!
For detailed information about nucleotide diphosphokinase, go to the full flat file.
Word Map on EC 2.7.6.4
Reaction
Synonyms
ATP nucleotide 3'-pyrophosphokinase, ATP:nucleotide pyrophosphotransferase, nucleotide 3'-pyrophosphokinase, nucleotide pyrophosphokinase, nucleotide pyrophosphotransferase, pyrophosphokinase, nucleotide
ECTree
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Metals Ions on EC 2.7.6.4 - nucleotide diphosphokinase
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METALS and IONS 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
Co2+
Fe2+
Mg2+
Mn2+
Ni2+
-
absolute requirement for bivalent cations, at pH 10.0 Mg2+ is most effective, while Mn2+, Co2+ and Zn2+ show little activity. At pH 7.0, Co2+ is most effective and Mg2+, Mn2+, Ni2+ and Fe2+ show little activity
Zn2+
Co2+
-
absolute requirement for a divalent metal ion, at pH 10.0 Mg2+ and Mn2+ are most effective, at pH 7.0 Mg2+, Co2+, Mn2+, Fe2+ and Zn2+ are effective
Co2+
-
absolute requirement for bivalent cations, at pH 10.0 Mg2+ is most effective, while Mn2+, Co2+ and Zn2+ show little activity. At pH 7.0, Co2+ is most effective and Mg2+, Mn2+, Ni2+ and Fe2+ show little activity. Optimal concentration is 2.5 mM Co2+
Fe2+
-
absolute requirement for a divalent metal ion, at pH 10.0 Mg2+ and Mn2+ are most effective, at pH 7.0 Mg2+, Co2+, Mn2+, Fe2+ and Zn2+ are effective
Fe2+
-
absolute requirement for bivalent cations, at pH 10.0 Mg2+ is most effective, while Mn2+, Co2+ and Zn2+ show little activity. At pH 7.0, Co2+ is most effective and Mg2+, Mn2+, Ni2+ and Fe2+ show little activity
Mg2+
-
absolute requirement for a divalent metal ion, at pH 10.0, Mg2+ and Mn2+ are most effective. At pH 7.0, Mg2+, Co2+, Mn2+, Fe2+ and Zn2+ are effective
Mg2+
-
absolute requirement for bivalent cations, at pH 10.0, Mg2+ is most effective, while Mn2+, Co2+ and Zn2+ show little activity. At pH 7.0, Co2+ is most effective and Mg2+, Mn2+, Ni2+ and Fe2+ show little activity. Optimal concentration is 5 mM Mg2+
Mg2+
-
most actively stimulates at 30-100 mM, half-maximal activation from 10 to 100 mM
Mn2+
-
absolute requirement for a divalent metal ion, at pH 10.0 Mg2+ and Mn2+ are most effective, at pH 7.0 Mg2+, Co2+, Mn2+, Fe2+ and Zn2+ are effective
Mn2+
-
absolute requirement for bivalent cations, at pH 10.0 Mg2+ is most effective, while Mn2+, Co2+ and Zn2+ show little activity. At pH 7.0, Co2+ is most effective and Mg2+, Mn2+, Ni2+ and Fe2+ show little activity
Zn2+
-
absolute requirement for a divalent metal ion, at pH 10.0 Mg2+ and Mn2+ are most effective, at pH 7.0 Mg2+, Co2+, Mn2+, Fe2+ and Zn2+ are effective
