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2.7.7.13: mannose-1-phosphate guanylyltransferase

This is an abbreviated version!
For detailed information about mannose-1-phosphate guanylyltransferase, go to the full flat file.

Word Map on EC 2.7.7.13

Reaction

GTP
+
alpha-D-mannose 1-phosphate
=
diphosphate
 +
GDP-mannose

Synonyms

BceA, BceA(J) protein, BceAJ, CYT1, GDP-alpha-D-mannose pyrophosphorylase, GDP-D-mannose pyrophosphorylase, GDP-Man pyrophosphorylase, GDP-mannose pyrophosphorylase, GDP-mannose pyrophosphorylase B, GDP-ManPP, GDP-MP, GDPMan pyrophosphorylase, GMP, GMP3, GMPase, GMPBB, GMPP, GMPP1, GMPP2, GMPP3, GMPPB, GTP-alpha-D-Man-1-P guanylyltransferase, GTP-mannose 1-phosphate guanylyltransferase, GTP-mannose-1-phosphate guanylyltransferase, guanidine diphosphomannose pyrophosphorylase, guanidine diphosphomannose pyrophoyphorylase, guanosine 5'-diphosphate-mannose pyrophosphorylase, guanosine 5'-diphospho-D-mannose pyrophosphorylase, guanosine diphosphate mannose pyrophosphorylase, guanosine diphosphate mannose pyrophosphorylase B, guanosine diphosphate-mannose pyrophosphorylase, guanosine diphosphomannose pyrophosphorylase, guanosine triphosphate-mannose 1-phosphate guanylyltransferase, guanosine-diphospho-D-mannose pyrophosphorylase, guanylyltransferase, mannose 1-phosphate, LDBPK_230120, Man-1-PGTase, mannose 1-phosphate guanyltransferase, mannose 1-phosphate guanylyltransferase (guanosine triphosphate), mannose-1-phosphate guanyl transferase, mannose-1-phosphate guanyltransferase beta, mannose-1-phosphate guanylyltransferase, More, MPG, MPG transferase, multiple sugar-1-P NTase, NDP-sugar pyrophosphorylase, NSPase, Os01g0847200, Os03g0268400, OsVTC1-1, OsVTC1-3, OsVTC1-8, PFManC, PH0925, PH0925 protein, PIM-GMP, RfbM, VCT1-1, VCT1-3, VTC1, VTC1-1, VTC1-3

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.7 Nucleotidyltransferases
                2.7.7.13 mannose-1-phosphate guanylyltransferase

Substrates Products

Substrates Products on EC 2.7.7.13 - mannose-1-phosphate guanylyltransferase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
8-Azido-GTP + glucose 1-phosphate
8-Azido-GDPglucose + diphosphate
show the reaction diagram
-
-
-
?
8-Azido-GTP + mannose 1-phosphate
8-Azido-GDP mannose + diphosphate
show the reaction diagram
-
-
-
?
ATP + alpha-D-mannose 1-phosphate
ADPmannose + diphosphate
show the reaction diagram
-
recombinant beta subunit of GDPmannose pyrophosphorylase, 18% of activity with GTP
-
?
ATP + alpha-D-mannose 1-phosphate
alpha-ADP-mannose + diphosphate
show the reaction diagram
-
-
-
-
?
ATP + alpha-D-mannose 1-phosphate
diphosphate + ADP-mannose
show the reaction diagram
about 8% of the activity with GTP
-
-
?
ATP + D-mannose 1-phosphate
diphosphate + ADP-mannose
show the reaction diagram
-
-
-
?
CTP + alpha-D-mannose 1-phosphate
alpha-CDP-mannose + diphosphate
show the reaction diagram
-
-
-
-
?
CTP + alpha-D-mannose 1-phosphate
diphosphate + CDP-alpha-D-mannose
show the reaction diagram
-
recombinant beta subunit of GDPmannose pyrophosphorylase, 7% of activity with GTP
-
?
CTP + alpha-D-mannose 1-phosphate
diphosphate + CDP-mannose
show the reaction diagram
about 8% of the activity with GTP
-
-
?
D-mannose 1-phosphate + GTP
GDP-D-mannose + diphosphate
show the reaction diagram
-
-
-
-
?
dGTP + alpha-D-mannose 1-phosphate
dGDPmannose + diphosphate
show the reaction diagram
dGTP + alpha-D-mannose 1-phosphate
diphosphate + dGDP-mannose
show the reaction diagram
high activity
-
-
?
diphosphate + GDP-alpha-D-mannose
GTP + alpha-D-mannose 1-phosphate
show the reaction diagram
diphosphate + GDP-mannose
GTP + alpha-D-mannose 1-phosphate
show the reaction diagram
dTTP + alpha-D-mannose 1-phosphate
alpha-dTDP-mannose + diphosphate
show the reaction diagram
-
-
-
-
?
GDP-glucose + diphosphate
D-glucose 1-phosphate + GTP
show the reaction diagram
-
most effective substrate in direction of nucleoside triphosphate formation, in the reverse direction GTP is a better glucose acceptor than ITP
-
r
GDP-mannose + diphosphate
GTP + D-mannose 1-phosphate
show the reaction diagram
GDPmannose + diphosphate
?
show the reaction diagram
-
61% of the activity with GDPglucose
-
-
r
GTP + 2-deoxy-alpha-D-glucose-1-phosphate
GDP-2-deoxy-alpha-D-glucose + diphosphate
show the reaction diagram
-
recombinant GDPmannose pyrophosphorylase, 15% of activity with mannose 1-phosphate
-
?
GTP + 2-O-methyl-alpha-D-mannose 1-phosphate
diphosphate + GDP-2-O-methyl-alpha-D-mannose
show the reaction diagram
-
-
-
-
?
GTP + 3-deoxy-alpha-D-arabino-hexose-1-phosphate
GDP-3-deoxy-alpha-D-arabino-hexose + diphosphate
show the reaction diagram
-
recombinant GDPmannose pyrophosphorylase, 70% of activity with mannose 1-phosphate
-
?
GTP + 3-O-methyl-alpha-D-mannose 1-phosphate
diphosphate + GDP-3-O-methyl-alpha-D-mannose
show the reaction diagram
-
-
-
-
?
GTP + 4-deoxy-alpha-D-lyxo-hexose 1-phosphate
GDP-4-deoxy-alpha-D-lyxo-hexose + diphosphate
show the reaction diagram
-
-
-
-
?
GTP + 4-deoxy-alpha-D-lyxo-hexose-1-phosphate
GDP-4-deoxy-alpha-D-lyxo-hexose + diphosphate
show the reaction diagram
-
recombinant GDPmannose pyrophosphorylase, 22% of activity with mannose 1-phosphate
-
?
GTP + 4-O-methyl-alpha-D-mannose 1-phosphate
diphosphate + GDP-4-O-methyl-alpha-D-mannose
show the reaction diagram
-
-
-
-
?
GTP + 6-O-methyl-alpha-D-mannose 1-phosphate
diphosphate + GDP-6-O-methyl-alpha-D-mannose
show the reaction diagram
-
-
-
-
?
GTP + alpha-D-galactose 1-phosphate
GDP-alpha-D-galactose + diphosphate
show the reaction diagram
-
-
-
-
?
GTP + alpha-D-glucosamine 1-phosphate
alpha-GDP-glucosamine + diphosphate
show the reaction diagram
-
-
-
-
?
GTP + alpha-D-glucosamine 1-phosphate
diphosphate + GDP-alpha-D-glucosamine
show the reaction diagram
-
-
-
?
GTP + alpha-D-glucose 1-phosphate
alpha-GDP-glucose + diphosphate
show the reaction diagram
-
-
-
-
?
GTP + alpha-D-glucose 1-phosphate
diphosphate + GDP-glucose
show the reaction diagram
-
-
-
-
?
GTP + alpha-D-lyxose-1-phosphate
GDP-alpha-D-lyxose + diphosphate
show the reaction diagram
-
-
-
-
?
GTP + alpha-D-lyxose-1-phosphate
GDPalpha-D-lyxose + diphosphate
show the reaction diagram
-
recombinant GDPmannose pyrophosphorylase, 12% of activity with mannose 1-phosphate
-
?
GTP + alpha-D-mannose 1-phosphate
alpha-GDP-mannose + diphosphate
show the reaction diagram
-
in the presence of diphosphatase
-
-
r
GTP + alpha-D-mannose 1-phosphate
diphosphate + GDP-alpha-D-mannose
show the reaction diagram
GTP + alpha-D-mannose 1-phosphate
diphosphate + GDP-D-mannose
show the reaction diagram
-
-
-
?
GTP + alpha-D-mannose 1-phosphate
diphosphate + GDP-mannose
show the reaction diagram
GTP + alpha-D-mannose 1-phosphate
GDPmannose + diphosphate
show the reaction diagram
GTP + alpha-D-mannose 1-phosphate + GTP
diphosphate + GDP-alpha-D-mannose
show the reaction diagram
-
-
-
-
?
GTP + alpha-L-fucose 1-phosphate
GDP-alpha-L-fucose + diphosphate
show the reaction diagram
-
-
-
-
?
GTP + alpha-N-acetyl-D-glucosamine 1-phosphate
GDP-alpha-N-acetyl-D-glucosamine + diphosphate
show the reaction diagram
-
-
-
-
?
GTP + D-mannose 1-phosphate
diphosphate + GDP-mannose
show the reaction diagram
IDPmannose + diphosphate
ITP + mannose 1-phosphate
show the reaction diagram
-
72% of activity with GDPglucose
-
r
ITP + alpha-D-mannose 1-phosphate
IDPmannose + diphosphate
show the reaction diagram
ITP + glucose 1-phosphate
IDP-glucose + diphosphate
show the reaction diagram
-
-
-
?
UTP + alpha-D-mannose 1-phosphate
alpha-UDP-mannose + diphosphate
show the reaction diagram
-
-
-
-
?
UTP + alpha-D-mannose 1-phosphate
diphosphate + UDP-mannose
show the reaction diagram
about 8% of the activity with GTP
-
-
?
UTP + alpha-D-mannose 1-phosphate
UDPmannose + diphosphate
show the reaction diagram
-
recombinant beta subunit of GDPmannose pyrophosphorylase, 12% of activity with GTP
-
?
additional information
?
-