2.7.7.14: ethanolamine-phosphate cytidylyltransferase
This is an abbreviated version!
For detailed information about ethanolamine-phosphate cytidylyltransferase, go to the full flat file.
Word Map on EC 2.7.7.14
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2.7.7.14
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phosphatidylethanolamine
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phospholipid
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cdp-ethanolamine
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diacylglycerols
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kennedy
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cdp-choline
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ctp:phosphocholine
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phosphocholine
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3hethanolamine
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ptdetn
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ethanolaminephosphotransferase
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14cethanolamine
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drug development
- 2.7.7.14
- phosphatidylethanolamine
- phospholipid
- cdp-ethanolamine
- diacylglycerols
-
kennedy
- cdp-choline
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ctp:phosphocholine
- phosphocholine
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3hethanolamine
-
ptdetn
- ethanolaminephosphotransferase
-
14cethanolamine
- drug development
Reaction
Synonyms
CTP-phosphoethanolamine cytidylyltransferase, CTP:ethanolaminephosphate cytidylyltransferase, CTP:phosphoethanolamine CT, CTP:phosphoethanolamine cytidylyltransferase, CTP:phosphoethanolamine cytidylyltransferase gene, cytidylyltransferase, ethanolamine phosphate, ECT, ET, ethanolamine phosphate cytidylyltransferase, ethanolamine-phosphate cytidylyltransferase, Pcyt2, Pcyt2alpha, Pcyt2beta, PECT1, phosphoethanolamine cytidyltransferase, phosphoethanolamine cytidylyltransferase, phosphorylethanolamine transferase, Tb11.01.5730
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Disease
Disease on EC 2.7.7.14 - ethanolamine-phosphate cytidylyltransferase
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Atherosclerosis
Liver X Receptor Agonists Inhibit the Phospholipid Regulatory Gene CTP: Phosphoethanolamine Cytidylyltransferase-Pcyt2.
Breast Neoplasms
Breast cancer cells adapt to metabolic stress by increasing ethanolamine phospholipid synthesis and CTP:ethanolaminephosphate cytidylyltransferase-Pcyt2 activity.
Breast Neoplasms
Characterization of transcription factors and cis-acting elements that regulate human CTP: phosphoethanolamine cytidylyltransferase (Pcyt2).
Breast Neoplasms
Liver X Receptor Agonists Inhibit the Phospholipid Regulatory Gene CTP: Phosphoethanolamine Cytidylyltransferase-Pcyt2.
Breast Neoplasms
Phosphoethanolamine Accumulation Protects Cancer Cells under Glutamine Starvation through Downregulation of PCYT2.
Dwarfism
Defects in CTP:PHOSPHORYLETHANOLAMINE CYTIDYLYLTRANSFERASE affect embryonic and postembryonic development in Arabidopsis.
Epilepsy
Mutations in PCYT2 disrupt etherlipid biosynthesis and cause a complex hereditary spastic paraplegia.
ethanolamine-phosphate cytidylyltransferase deficiency
Choline supplementation restores substrate balance and alleviates complications of Pcyt2 deficiency.
ethanolamine-phosphate cytidylyltransferase deficiency
Mechanism of hypertriglyceridemia in CTP:phosphoethanolamine cytidylyltransferase-deficient mice.
ethanolamine-phosphate cytidylyltransferase deficiency
The development of a metabolic disease phenotype in CTP:phosphoethanolamine cytidylyltransferase-deficient mice.
Fatty Liver
Mechanism of hypertriglyceridemia in CTP:phosphoethanolamine cytidylyltransferase-deficient mice.
Fatty Liver
The development of a metabolic disease phenotype in CTP:phosphoethanolamine cytidylyltransferase-deficient mice.
Hypertriglyceridemia
Mechanism of hypertriglyceridemia in CTP:phosphoethanolamine cytidylyltransferase-deficient mice.
Hypertriglyceridemia
The development of a metabolic disease phenotype in CTP:phosphoethanolamine cytidylyltransferase-deficient mice.
Insulin Resistance
Mechanism of hypertriglyceridemia in CTP:phosphoethanolamine cytidylyltransferase-deficient mice.
Insulin Resistance
The development of a metabolic disease phenotype in CTP:phosphoethanolamine cytidylyltransferase-deficient mice.
Insulin Resistance
Type 2 diabetes-related proteins derived from an in vitro model of inflamed fat tissue.
Metabolic Syndrome
Mechanism of hypertriglyceridemia in CTP:phosphoethanolamine cytidylyltransferase-deficient mice.
Metabolic Syndrome
The development of a metabolic disease phenotype in CTP:phosphoethanolamine cytidylyltransferase-deficient mice.
Muscle Spasticity
Mutations in PCYT2 disrupt etherlipid biosynthesis and cause a complex hereditary spastic paraplegia.
Neoplasms
Breast cancer cells adapt to metabolic stress by increasing ethanolamine phospholipid synthesis and CTP:ethanolaminephosphate cytidylyltransferase-Pcyt2 activity.
Neoplasms
Phosphoethanolamine Accumulation Protects Cancer Cells under Glutamine Starvation through Downregulation of PCYT2.
Obesity
Mechanism of hypertriglyceridemia in CTP:phosphoethanolamine cytidylyltransferase-deficient mice.
Obesity
The development of a metabolic disease phenotype in CTP:phosphoethanolamine cytidylyltransferase-deficient mice.
Parkinson Disease
Elevated activity of phospholipid biosynthetic enzymes in substantia nigra of patients with Parkinson's disease.
Spastic Paraplegia, Hereditary
A novel PCYT2 mutation identified in a Chinese consanguineous family with hereditary spastic paraplegia.
Spastic Paraplegia, Hereditary
Mutations in PCYT2 disrupt etherlipid biosynthesis and cause a complex hereditary spastic paraplegia.
Starvation
Phosphoethanolamine Accumulation Protects Cancer Cells under Glutamine Starvation through Downregulation of PCYT2.
Starvation
Transcriptional suppression of CTP:phosphoethanolamine cytidylyltransferase by 25-hydroxycholesterol is mediated by nuclear factor-Y and Yin Yang 1.
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