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2.7.7.18: nicotinate-nucleotide adenylyltransferase

This is an abbreviated version!
For detailed information about nicotinate-nucleotide adenylyltransferase, go to the full flat file.

Word Map on EC 2.7.7.18

Reaction

ATP
+
beta-nicotinate D-ribonucleotide
=
diphosphate
+
deamido-NAD+

Synonyms

adenylyltransferase, nicotinate mononucleotide, Arabidopsis thaliana nicotinate/nicotinamide mononucleotide adenyltransferase, AtNMNAT, deamido-NAD+ pyrophosphorylase, deamidonicotinamide adenine dinucleotide pyrophosphorylase, GlNMNAT, M6_Spy0291, nadD, NaMN AT, NaMN-ATase, NaMNAT, nicotinamide/nicotinate mononucleotide adenylyltransferase, nicotinamide/nicotinic acid mononucleotide adenylyltransferase, nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1, nicotinate mononucleotide adenylyltransferase, nicotinate/nicotinamide mononucleotide adenyltransferase, nicotinic acid mononucleotide adenylyltransferase, NMN/NaMN adenylyltransferase, NMN/NaMN adenylyltransferase 2, NMN/NaMN adenylyltransferase 3, NMNAT, NMNAT1, NMNAT2, NMNAT3, PF3D7_1327600, PfNMNAT, sp.NadD, TTHA1780

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.7 Nucleotidyltransferases
                2.7.7.18 nicotinate-nucleotide adenylyltransferase

Cloned

Cloned on EC 2.7.7.18 - nicotinate-nucleotide adenylyltransferase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expression in Escherichia coli
expression in Escherichia coli NZN111 with IdhA and pflB genes inactivated for the production of succinic acid
-
expression in HeLa S3 cells
gene nadD, overexpression of the His-tagged enzyme in Escherichia coli strain BL21(DE3)
gene nadD, sequence comparisons, recombinant expression of N-terminally His6-tagged wild-type and mutant enzymes in Escherichia coli strain BL21(DE3)
gene PF13_0159, phylogenetic tree, recombinant expression of His6-tagged enzyme in Escherichia coli strain BL21 (RIL Codon PLUS), recombinant expression of GFP-tagged enzyme in Plasmodium falciparum ring stage D10 culture cells
genes glnmnat-a and glnmnat-b, encoded on chromosome 3 and 5, respectively, DNA and amino acid sequence determination and analysis, phylogenetic analysis of GlNMNAT isoenzymes, sequence comparisons to human isozymes, recombinant expression of His-tagged glnmnat-a gene product in Escherichia coli strain BL21
overexpression in Escherichia coli BL21 with a 6 x His-tag
overexpression in Escherichia coli BL21 with a His-tag
-