Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.7.7.19: polynucleotide adenylyltransferase

This is an abbreviated version!
For detailed information about polynucleotide adenylyltransferase, go to the full flat file.

Word Map on EC 2.7.7.19

Reaction

ATP
+
RNAn
=
diphosphate
 +
RNAn+3'-A

Synonyms

AAS, adenosine triphosphate:ribonucleic acid adenylyltransferase, AMP polynucleotidylexotransferase, ATP-polynucleotide adenylyltransferase, ATP:polynucleotidylexotransferase, CC-adding enzyme, Cid1, Cid14, FAM46A, FAM46B, FAM46C, FAM46D, germline development 2, GLD-2, GLD2, GLD4, Hs2, MTPAP, neo-PAP, non-canonical poly(A) RNA polymerase PAPD7, NTP polymerase, nuclear poly(A) polymerase 1, nuclear speckle targeted PIPKIalpha regulated-poly(A) polymerase, nucleotidyltransferase, polyadenylate, PAP, PAP I, Pap II, PAP1, Pap1p, PAPalpha, PAPbeta, PapD1, PapD5, PAPD7, PAPgamma, PAPOLA, PAPOLB/TPAP, PAPOLG, PAPS1, PAPS2, PAPS4, PcnB, pcnB2, pcnB2 aq_2158, poly A polymerase, poly(A) hydrolase, poly(A) polymerase, poly(A) polymerase gamma, poly(A) polymerase I, poly(A) polymerase II, poly(A) RNA polymerase protein 1, poly(A) synthetase, poly(A)-polymerase, poly(A)polymerase I, polyA polymerase, polyadenylate nucleotidyltransferase, polyadenylate polymerase, polyadenylate synthetase, polyadenylic acid polymerase, polyadenylic polymerase, poly[A] polymerase beta, RNA adenylating enzyme, RNA formation factors, PF1, RNA poly(A) polymerase, Star-PAP, Tb927.3.3160, Tb927.7.3780, terminal riboadenylate transferase, Tpap, Trf5, Trf5p, TUT1, TUTase1, VP55, Wisp, yPAP, ZCCHC6

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.7 Nucleotidyltransferases
                2.7.7.19 polynucleotide adenylyltransferase

Activating Compound

Activating Compound on EC 2.7.7.19 - polynucleotide adenylyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
3',5'-AMP
-
slight stimulation
Dinucleotide
-
in presence of 0.5 mM ATP, activation in decreasing order: GP4G, GP3G, AP6A, GP2G, AP4A, AP2A, GP5G, AP5A, AP3A, activation at 0.01 mM is 4-10fold
dithiothreitol
-
required
germ cell-specific gene 1 protein
TPAP interaction partner protein leading to redistribution of TPAP from the cytosol to the endoplasmic reticulum
-
host factor I
-
Hfq-PAP I interaction facilitates RNA recognition by PAP I
-
KCl
-
major poly(A) polymerase, optimal at 250 mM, minor poly(A) polymerase, optimal at 125 mM, inhibition of both above 250 mM
phosphatidylinositol 4,5-bisphosphate
-
in the presence of 50 mM phosphatidylinositol 4,5-bisphosphate Star-PAP activity is markedly stimulated
Poly(U)
-
stimulates
spermidine
-
slight stimulation, 5 mM
additional information
-