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2.7.7.24: glucose-1-phosphate thymidylyltransferase

This is an abbreviated version!
For detailed information about glucose-1-phosphate thymidylyltransferase, go to the full flat file.

Word Map on EC 2.7.7.24

Reaction

dTTP
+
alpha-D-glucose 1-phosphate
=
diphosphate
+
dTDP-alpha-D-glucose

Synonyms

Cps23FL, Cps2L, D-glucose-1-phosphate thymidylyltransferase, DnmL, dTDP-alpha-D-glucose pyrophosphorylase, dTDP-D-glucose synthase, dTDP-glucose synthase, dTDP-glucose-pyrophosphorylase, dTDPglucose pyrophosphorylase, Glc-1-P thymidylyltransferase, Glc-1-P TTase, Glc-1-P-TT, Glc1P-thymidylyltransferase, glucose 1-phosphate thymidylyltransferase, glucose-1-phosphate thymidylyltransferase, RfbA, rml-1, RmlA, RmlA protein, SchS6, SgcA1, ST0452, sugar-1-phosphate nucleotidyltransferase, TDP-glucose pyrophosphorylase, thymidine diphosphate glucose pyrophosphorylase, thymidine diphosphoglucose pyrophosphorylase, thymidylyltransferase, glucose 1-phosphate, ugpG, UgpG protein, UTP/dTTP-glucose-1-phosphate uridylyl/thymidylyl transferase

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.7 Nucleotidyltransferases
                2.7.7.24 glucose-1-phosphate thymidylyltransferase

KM Value

KM Value on EC 2.7.7.24 - glucose-1-phosphate thymidylyltransferase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.69 - 0.7
2-deoxy-2-amino-alpha-D-glucose 1-phosphate
1.1
3-deoxy-3-amino-alpha-D-glucose 1-phosphate
-
cosubstrate dTTP, pH 7.5, temperature not specified in the publication
1.1
3-deoxy-3-azido-alpha-D-glucose 1-phosphate
-
cosubstrate dTTP, pH 7.5, temperature not specified in the publication
0.03224 - 1.12
alpha-D-glucose 1-phosphate
0.336 - 9
ATP
0.276 - 13.7
CTP
1.1 - 7.8
dATP
10.5
dCTP
3.7 - 11.5
dGTP
0.154 - 0.39
diphosphate
0.05
dTDP-alpha-D-glucose
0.0094 - 0.095
dTDP-glucose
0.0106 - 6.2
dTTP
0.184 - 8.5
GTP
0.05
TDP-glucose
-
25°C, pH 8
0.1
TTP
-
25°C, pH 8
0.00947 - 4.6
UTP
0.18 - 0.38
[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]methyl]phosphonic acid