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2.7.7.40: D-ribitol-5-phosphate cytidylyltransferase

This is an abbreviated version!
For detailed information about D-ribitol-5-phosphate cytidylyltransferase, go to the full flat file.

Word Map on EC 2.7.7.40

Reaction

CTP
+
D-ribitol 5-phosphate
=
diphosphate
+
CDP-ribitol

Synonyms

Bcs1, CDP-L-ribitol pyrophosphorylase A, CDP-ribitol (ribose) pyrophosphorylase, CDP-ribitol pyrophosphorylase, CDP-ribitol synthase, CDPribitol pyrophosphorylase, CRPPA, cytidine diphosphate ribitol pyrophosphorylase, cytidine diphosphate-l-ribitol pyrophosphorylase A, Cytidine diphosphoribitol pyrophosphorylase, cytidylyltransferase, cytidylyltransferase, ribitol 5-phosphate, isoprenoid synthase domain-containing protein, IspD, ribitol 5-phosphate cytidylyltransferase, TarI, TarIJ

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.7 Nucleotidyltransferases
                2.7.7.40 D-ribitol-5-phosphate cytidylyltransferase

Reference

Reference on EC 2.7.7.40 - D-ribitol-5-phosphate cytidylyltransferase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Shaw, D.R.D.
Phosphorolysis and enzymic synthesis of cytidine diphosphate glycerol and cytidine diphosphate ribitol
Biochem. J.
82
297-312
1962
Bacillus subtilis, Saccharomyces cerevisiae, Chlorella vulgaris, Lactiplantibacillus plantarum, Lactococcus lactis, Staphylococcus aureus, Propionibacterium freudenreichii subsp. shermanii
Manually annotated by BRENDA team
Cheah, S.C.; Hussey, H.; Baddiley, J.
Control of synthesis of wall teichoic acid in phosphate-starved cultures of Bacillus subtilis W23
Eur. J. Biochem.
118
497-500
1981
Bacillus subtilis, Bacillus subtilis W23
Manually annotated by BRENDA team
Follens, A.; Veiga-da-Cunha, M.; Merckx, R.; van Schaftingen, E.; van Eldere, J.
acs1 of Haemophilus influenzae type a capsulation locus region II encodes a bifunctional ribulose 5-phosphate reductase- CDP-ribitol pyrophosphorylase
J. Bacteriol.
181
2001-2007
1999
Haemophilus influenzae
Manually annotated by BRENDA team
Zolli, M.; Kobric, D.J.; Brown, E.D.
Reduction precedes cytidylyl transfer without substrate channeling in distinct active sites of the bifunctional CDP-ribitol synthase from Haemophilus influenzae
Biochemistry
40
5041-5048
2001
Haemophilus influenzae
Manually annotated by BRENDA team
Pereira, M.P.; Brown, E.D.
Bifunctional catalysis by CDP-ribitol synthase: convergent recruitment of the reductase and cytidylyltransferase activities in Haemophilus influenzae and Staphylococcus aureus
Biochemistry
43
11802-11812
2004
Haemophilus influenzae, Staphylococcus aureus
Manually annotated by BRENDA team
Allali-Hassani, A.; Pereira, M.P.; Navani, N.K.; Brown, E.D.; Li, Y.
Isolation of DNA aptamers for CDP-ribitol synthase, and characterization of their inhibitory and structural properties
Chembiochem
8
2052-2057
2007
Haemophilus influenzae
Manually annotated by BRENDA team
Chen, S.C.; Yang, C.S.; Lin, C.T.; Chan, N.L.; Chang, M.C.; Chen, Y.
Expression, purification, crystallization and preliminary X-ray analysis of ribitol-5-phosphate cytidylyltransferase from Bacillus subtilis
Acta Crystallogr. Sect. F
68
1195-1197
2012
Bacillus subtilis (Q8RKI9)
Manually annotated by BRENDA team
Praissman, J.L.; Willer, T.; Sheikh, M.O.; Toi, A.; Chitayat, D.; Lin, Y.Y.; Lee, H.; Stalnaker, S.H.; Wang, S.; Prabhakar, P.K.; Nelson, S.F.; Stemple, D.L.; Moore, S.A.; Moremen, K.W.; Campbell, K.P.; Wells, L.
The functional O-mannose glycan on alpha-dystroglycan contains a phospho-ribitol primed for matriglycan addition
eLife
5
e14473
2016
Homo sapiens (A4D126), Homo sapiens
Manually annotated by BRENDA team
van Tol, W.; van Scherpenzeel, M.; Alsady, M.; Riemersma, M.; Hermans, E.; Kragt, E.; Tasca, G.; Kamsteeg, E.J.; Pennings, M.; van Beusekom, E.; Vermeulen, J.R.; van Bokhoven, H.; Voermans, N.C.; Willemsen, M.A.; Ashikov, A.; Lefeber, D.J.
Cytidine diphosphate-ribitol analysis for diagnostics and treatment monitoring of cytidine diphosphate-l-ribitol pyrophosphorylase A muscular dystrophy
Clin. Chem.
65
1295-1306
2019
Homo sapiens (A4D126), Homo sapiens, Mus musculus (Q5RJG7), Mus musculus
Manually annotated by BRENDA team
Gerin, I.; Ury, B.; Breloy, I.; Bouchet-Seraphin, C.; Bolsee, J.; Halbout, M.; Graff, J.; Vertommen, D.; Muccioli, G.G.; Seta, N.; Cuisset, J.M.; Dabaj, I.; Quijano-Roy, S.; Grahn, A.; Van Schaftingen, E.; Bommer, G.T.
ISPD produces CDP-ribitol used by FKTN and FKRP to transfer ribitol phosphate onto alpha-dystroglycan
Nat. Commun.
7
11534
2016
Mus musculus (Q5RJG7)
Manually annotated by BRENDA team