2.7.7.42: [glutamine synthetase] adenylyltransferase

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For detailed information about [glutamine synthetase] adenylyltransferase, go to the full flat file.

Reaction

Synonyms

adenosine triphosphate:glutamine synthetase adenylyltransferase, adenylyltransferase, adenylyltransferase, glutamine synthetase, ATASE, ATP:glutamine synthetase adenylyltransferase, ATP:[L-glutamate:ammonia ligase (ADP-forming)] adenylyl transferase, GlnE, glutamine synthetase adenylyl transferase, glutamine synthetase adenylyltransferase, glutamine synthetase ATase, glutamine-synthetase adenylyltransferase, GS ATase, [glutamate-ammonia-ligase] adenylyltransferase

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.7 Nucleotidyltransferases

                2.7.7.42 [glutamine synthetase] adenylyltransferase

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Results	in table
42	Activating Compound
16628	AA Sequence
1	CAS Registry Number
8	Cloned(Commentary)
17	Cofactor
4	Crystallization (Commentary)
2	Expression
7	General Information
5	General Stability
34	Inhibitors
10	Ki Value [mM]
18	KM Value [mM]
23	Metals/Ions
5	Molecular Weight [Da]
22	Natural Substrates/ Products (Substrates)
946	Organism
3	PDB ID
9	pH Optimum
1	pH Range
3	pH Stability
2	pI Value
26	Protein Variants
10	Purification (Commentary)
3	Reaction
6	Reaction Type
40	Reference
5	Specific Activity [micromol/min/mg]
3	Storage Stability
59	Substrates and Products (Substrate)
1	Subunits
46	Synonyms
1	Systematic Name
10	Temperature Optimum [°C]
1	Temperature Range [°C]

General Stability

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General Stability on EC 2.7.7.42 - [glutamine synthetase] adenylyltransferase

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GENERAL STABILITY

ORGANISM

UNIPROT

LITERATURE

bovine serum albumin, above 1 mg/ml, prevents inactivation at 4°C and 25°C and aggregation

Escherichia coli

-

643329, 643330

considerably less stable in Tris or imidazole buffer than in a magnesium phosphate buffer

Escherichia coli

-

643334

Mg2+, 20 mM protects to some extent against heat inactivation

Escherichia coli

-

643329

no stabilization by ATP, CTP, Mn2+, glutamine, cysteine or mercaptoethanol each at 20 mM, 2 mM DTT, 20% glycerol, sucrose, polyethyleneglycol or urea at 1 M

Escherichia coli

-

643329