2.7.7.46: gentamicin 2''-nucleotidyltransferase
This is an abbreviated version!
For detailed information about gentamicin 2''-nucleotidyltransferase, go to the full flat file.
Word Map on EC 2.7.7.46
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2.7.7.46
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aac3-ii
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tobramycin
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colistin
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integrons
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nucleotidylated
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aminoglycoside-modifying
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aac6'-ie
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aph3\'-vi
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amikacin
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extended-spectrum
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esbls
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medicine
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theorell-chance
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blandm-1
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northrop
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colistin-resistant
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co-harboured
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genre
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carbapenemases
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gentamicin-resistant
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netilmicin
- 2.7.7.46
-
aac3-ii
- tobramycin
- colistin
- integrons
-
nucleotidylated
-
aminoglycoside-modifying
-
aac6'-ie
-
aph3\'-vi
- amikacin
-
extended-spectrum
-
esbls
- medicine
-
theorell-chance
- blandm-1
-
northrop
-
colistin-resistant
-
co-harboured
-
genre
- carbapenemases
-
gentamicin-resistant
- netilmicin
Reaction
Synonyms
AAD 2'', aadB, aadB(ant2')Ia, aminoglycoside adenyltransferase 2''-Ia, aminoglycoside adenylyltransferase, aminoglycoside nucleotidyltransferase 2''-I, ANT(2'')-I, ANT(2'')-Ia, ANT2'', gentamicin 2''-adenylyltransferase, gentamicin nucleotidyltransferase
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Reference
Reference on EC 2.7.7.46 - gentamicin 2''-nucleotidyltransferase
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Angelatou, F.; Litsas, S.B.; Kontomichalou, P.
Purification and properties of two gentamicin-modifying enzymes, coded by a single plasmid pPK237 originating from Pseudomonas aeruginosa
J. Antibiot.
35
235-244
1982
Pseudomonas aeruginosa
Van Pelt, J.E.; Northrop, D.B.
Purification and properties of gentamicin nucleotidyltransferase from Escherichia coli: nucleotide specificity, pH optimum, and the separation of two electrophoretic variants
Arch. Biochem. Biophys.
230
250-263
1984
Escherichia coli
Yagisawa, M.; Naganawa, H.; Kondo, S.; Hamada, M.; Takeuchi, T.; Umezawa, H.
Adenylyldideoxykanamycin B, a product of the inactivation of dideoxykanamycin B by Escherichia coli carrying R factor
J. Antibiot.
26
911-912
1971
Escherichia coli, Escherichia coli JR66/W677
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Naganawa, H.; Yagisawa, M.; Kondo, S.; Takeuchi, T.; Umezawa, H.
The structure determination of an enzymatic inactivation product of 3',4'-dideoxykanamycin B
J. Antibiot.
26
913-914
1971
Escherichia coli, Escherichia coli JR66/W677
Gates, C.A.; Northrop, D.B.
Alternative substrate and inhibition kinetics of aminoglycoside nucleotidyltransferase 2''-I in support of a Theorell-Chance kinetic mechanism
Biochemistry
27
3826-3833
1988
Escherichia coli, Escherichia coli W677/pMY10
Gates, C.A.; Northrop, D.B.
Determination of the rate-limiting segment of aminoglycoside nucleotidyltransferase 2''-I by pH- and viscosity-dependent kinetics
Biochemistry
27
3834-3842
1988
Escherichia coli
Van Pelt, J.E.; Mooberry, E.S.; Frey, P.A.
1H, 13C, and 31P nuclear magnetic resonance spectral assignments for tobramycin, 2"-(adenosine-5'-phosphoryl)-tobramycin and 2"-(adenosine-5'-thiophosphoryl)-tobramycin
Arch. Biochem. Biophys.
280
284-291
1990
Escherichia coli
Ekman, D.R.; DiGiammarino, E.L.; Wright, E.; Witter, E.D.; Serpersu, E.H.
Cloning, overexpression, and purification of aminoglycoside antibiotic nucleotidyltransferase (2'')-Ia: conformational studies with bound substrates
Biochemistry
40
7017-7024
2001
Pseudomonas aeruginosa
Anderson, S.E.; Sherman, E.X.; Weiss, D.S.; Rather, P.N.
Aminoglycoside heteroresistance in Acinetobacter baumannii AB5075
mSphere
3
e00271-18
2018
Acinetobacter baumannii (B0VCJ4), Acinetobacter baumannii AB5075 (B0VCJ4)
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