2.7.7.5: sulfate adenylyltransferase (ADP)
This is an abbreviated version!
For detailed information about sulfate adenylyltransferase (ADP), go to the full flat file.
Word Map on EC 2.7.7.5
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2.7.7.5
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ap4a
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sulfite
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5',5'''-p1,p4-tetraphosphate
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diadenosine
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thiobacillus
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arsenolysis
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nucleoside
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cdp
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orthophosphate
- 2.7.7.5
- ap4a
- sulfite
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5',5'''-p1,p4-tetraphosphate
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diadenosine
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thiobacillus
-
arsenolysis
- nucleoside
- cdp
- orthophosphate
Reaction
Synonyms
adenosine 5'-phosphosulfate phosphorylase, adenosine diphosphate sulfurylase, adenylylsulfate:phosphate adenylyltransferase, ADP sulfurylase, ADP-sulfurylase, APS phosphorylase, Dcps, Hint4, More, sulfate (adenosine diphosphate) adenylyltransferase
ECTree
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Substrates Products
Substrates Products on EC 2.7.7.5 - sulfate adenylyltransferase (ADP)
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REACTION DIAGRAM
phosphate + adenosine 5'-phosphoamidate
ADP + NH4+
22% reaction velocity compared to adenosine 5'-phosphosulfate
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-
ir
phosphate + adenosine 5'-phosphofluoride
ADP + fluoride
8% reaction velocity compared to adenosine 5'-phosphosulfate
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-
?
phosphate + diadenosine tetraphosphate
?
2% reaction velocity compared to adenosine 5'-phosphosulfate
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-
?
phosphate + adenosine 5'-phosphosulfate
ADP + SO42-
100% reaction velocity
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-
ir
phosphate + adenosine 5'-phosphosulfate
ADP + SO42-
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100% reaction velocity
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-
ir
phosphate + adenosine 5'-phosphosulfate
ADP + SO42-
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-
-
?
phosphate + adenosine 5'-phosphosulfate
ADP + SO42-
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-
-
?
phosphate + adenosine 5'-phosphosulfate
ADP + SO42-
-
-
-
?
phosphate + adenosine 5'-phosphosulfate
ADP + SO42-
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ping pong reaction mechanism
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r
phosphate + adenosine 5'-phosphosulfate
ADP + SO42-
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role in production of sulfated and reduced sulfur compounds postulated
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?
phosphate + adenosine 5'-phosphosulfate
ADP + SO42-
-
-
?
phosphate + adenosine 5'-phosphosulfate
ADP + SO42-
ping pong reaction mechanism
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ir
phosphate + adenosine 5'-phosphosulfate
ADP + SO42-
highly specific for adenosine 5'-phosphosulfate
-
ir
phosphate + adenosine 5'-phosphosulfate
ADP + SO42-
-
-
?
phosphate + adenosine 5'-phosphosulfate
ADP + SO42-
ping pong reaction mechanism
-
ir
phosphate + adenosine 5'-phosphosulfate
ADP + SO42-
highly specific for adenosine 5'-phosphosulfate
-
ir
?
7% reaction velocity compared to adenosine 5'-phosphosulfate
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-
?
phosphate + diadenosine triphosphate
?
-
4% reaction velocity compared to adenosine 5'-phosphosulfate
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-
?
?
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the enzyme can act as a sulfohydrolase, catalyzing the liberation of AMP from adenosine 5'-phosphosulfate. However, in the presence of phosphate, the enzyme also behaves as adenosine 5'-phosphosulfate phosphorylases, forming ADP
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-
?
additional information
?
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when assayed in 0.1 M KH2PO4 with adenosine 5'-phosphosulfate, the enzyme cannot use diphosphate or triphosphate as potential adenylate acceptors in place of phosphate
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-
?
additional information
?
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-
the enzyme can act as a sulfohydrolase, catalyzing the liberation of AMP from adenosine 5'-phosphosulfate. However, in the presence of phosphate, the enzyme also behaves as adenosine 5'-phosphosulfate phosphorylases, forming ADP. The enzyme does not use adenosine 5'-phosphoamidate, adenosine 5'-phosphofluoride, and diadenosine tetraphosphate as substrates
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-
?
additional information
?
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when assayed in 0.1 M KH2PO4 with adenosine 5'-phosphosulfate, the enzyme cannot use diphosphate or tripolyphosphate as potential adenylate acceptors in place of phosphate
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-
?
additional information
?
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no activity with AMP, ATP or diphosphate
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-
?
additional information
?
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Saccharomyces fragilis
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several nucleotide derivatives tested for activity
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-
?
additional information
?
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no activity with ADP, CDP, GDP, UDP and IDP
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-
?
additional information
?
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no activity with ADP, CDP, GDP, UDP and IDP
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-
?
additional information
?
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no activity with ADP, CDP, GDP, UDP and IDP
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-
?