Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.7.7.53: ATP adenylyltransferase

This is an abbreviated version!
For detailed information about ATP adenylyltransferase, go to the full flat file.

Word Map on EC 2.7.7.53

Reaction

ADP
+
ATP
=
phosphate
 +
P1,P4-bis(5'-adenosyl) tetraphosphate

Synonyms

5',5'''-P1,P4-tetraphosphate phosphorylase, adenine triphosphate adenylyltransferase, adenylyltransferase, adenine triphosphate, AP-4-A phosphorylase, Ap3A/Ap4A phosphorylase, Ap4A phosphorylase, bis(5'-nucleosyl)-tetraphosphate phosphorylase (NDP-forming), diadenosine 5',5'''-P1,P4-tetraphosphate alpha,beta-phosphorylase, diadenosine 5',5'''-P1,P4-tetraphosphate alpha,beta-phosphorylase (ADP-forming), diadenosine 5',5'''-P1,P4-tetraphosphate alphabeta-phosphorylase (ADP-forming), diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase, diadenosinetetraphosphate alpha,beta-phosphorylase, diadenosinetetraphosphate alphabeta-phosphorylase, dinucleoside oligophosphate alphabeta-phosphorylase, MAV_3489, MEG_2932, Rv2613c

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.7 Nucleotidyltransferases
                2.7.7.53 ATP adenylyltransferase

Inhibitors

Inhibitors on EC 2.7.7.53 - ATP adenylyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
(11aR,13S,14R,15S,15aR)-2,3,4,5,6,7-hexahydroxy-9,17-dioxo-9,11,11a,13,14,15,15a,17-octahydrodibenzo[g,i]pyrano[3,2-b][1,5]dioxacycloundecine-13,14,15-triyl tris(3,4,5-trihydroxybenzoate)
29.96% activity remaining
1,2,3,4,6-pentakis-O-(3,4,5-trihydroxybenzoyl)-beta-D-glucopyranose
35.81% activity remaining
1,2,3,6-tetrakis-O-(3,4,5-trihydroxybenzoyl)-beta-D-glucopyranose
47.50% activity remaining
10-(3,4-dimethoxyphenyl)-7,7-dimethyl-7,8,10,10a-tetrahydro-6H-indeno[1,2-b]quinoline-9,11-dione
24.76% activity remaining
2-(4-chlorobenzene-1-sulfonyl)-3-(methylsulfanyl)-3-[3-(trifluoromethyl)anilino]propanenitrile
1.59% activity remaining
2-(benzenesulfonyl)-3-(3-ethylanilino)-3-(methylsulfanyl)propanenitrile
-
2-(benzenesulfonyl)-3-(3-methoxyanilino)-3-(methylsulfanyl)propanenitrile
-
2-(benzenesulfonyl)-3-(3-methylanilino)-3-(methylsulfanyl)propanenitrile
-
2-(benzenesulfonyl)-3-(benzylsulfanyl)-3-[3-(trifluoromethyl)anilino]propanenitrile
-
2-(benzenesulfonyl)-3-(ethylsulfanyl)-3-[3-(trifluoromethyl)anilino]propanenitrile
-
2-(benzenesulfonyl)-3-(methylsulfanyl)-3-(3-nitroanilino)propanenitrile
-
2-(benzenesulfonyl)-3-(methylsulfanyl)-3-(3-propylanilino)propanenitrile
-
2-(benzenesulfonyl)-3-(methylsulfanyl)-3-[2-(trifluoromethyl)anilino]propanenitrile
-
2-(benzenesulfonyl)-3-(methylsulfanyl)-3-[3-(propan-2-yl)anilino]propanenitrile
-
2-(benzenesulfonyl)-3-(methylsulfanyl)-3-[3-(trifluoromethyl)anilino]propanenitrile
docking structure
2-(benzenesulfonyl)-3-(methylsulfanyl)-3-[4-(trifluoromethyl)anilino]propanenitrile
-
2-(benzenesulfonyl)-3-(propylsulfanyl)-3-[3-(trifluoromethyl)anilino]propanenitrile
-
2-(benzenesulfonyl)-3-[(3,3-dimethylcyclohexa-1,5-dien-1-yl)amino]-3-(methylsulfanyl)propanenitrile
-
2-(benzenesulfonyl)-3-[(prop-2-en-1-yl)sulfanyl]-3-[3-(trifluoromethyl)anilino]propanenitrile
-
2-(benzenesulfonyl)-3-[(propan-2-yl)sulfanyl]-3-[3-(trifluoromethyl)anilino]propanenitrile
-
2-(benzenesulfonyl)-3-[[3,3-bis(trifluoromethyl)cyclohexa-1,5-dien-1-yl]amino]-3-(methylsulfanyl)propanenitrile
-
2-amino-3-[(E)-([2-[(4-chlorophenyl)sulfanyl]phenyl]methylidene)amino]butanedinitrile
46.29% activity remaining
2-amino-4-(3,4-dimethoxyphenyl)-7-methyl-3-nitro-4H,5H-pyrano[4,3-b]pyran-5-one
48.50% activity remaining
2-amino-5-(4-ethoxyphenyl)-5,11-dihydro-3H-indeno[2',1':5,6]pyrido[2,3-d]pyrimidine-4,6-dione
48.87% activity remaining
2-ethoxyethyl 4-(3-bromo-4-methoxyphenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate
31.80% activity remaining
2-iodo-5-[(4-methylphenyl)methyl]pyridin-3-ol
29.63% activity remaining
2-[(2-[[2-(3-fluoro-4-nitroanilino)-2-oxoethyl]sulfanyl]-1,3-benzothiazol-6-yl)carbamoyl]benzoic acid
43.56% activity remaining
2-[[6-amino-4-(2-chlorophenyl)-3,5-dicyanopyridin-2-yl]sulfanyl]-N-benzylacetamide
42.76% activity remaining
3-(3-chloro-4-hydroxy-5-methoxyphenyl)-2,3,6,7,8,9-hexahydro-5H-[1]benzothieno[2,3-d][1,3]thiazolo[3,2-a]pyrimidin-5-one
43.92% activity remaining
3-anilino-2-(4-chlorobenzene-1-sulfonyl)-3-(methylsulfanyl)propanenitrile
-
3-anilino-2-(benzenesulfonyl)-3-(methylsulfanyl)propanenitrile
-
3-[[2-(benzenesulfonyl)-2-cyano-1-(methylsulfanyl)ethyl]amino]benzonitrile
-
4-([[9-(3,4-dimethoxyphenyl)-8-oxo-4,5,6,7,8,9-hexahydro[1,2,4]triazolo[5,1-b]quinazolin-2-yl]sulfanyl]methyl)benzoic acid
33.53% activity remaining
5,5',6,6',8,8'-hexahydroxy-2,2'-dimethyl-2,2',3,3'-tetrahydro-4H,4'H-[9,9'-binaphtho[2,3-b]pyran]-4,4'-dione
no activity remaining
5-(2,4-dichlorophenyl)-2-methyl-2,3,5,6-tetrahydro-4H-pyrano[2,3-a][4,7]phenanthrolin-4-one
42.23% activity remaining
7-(4-chlorophenyl)-1,7-dimethyl-N-[2-(morpholin-4-yl)ethyl]-9-oxo-8,9-dihydro-7H-furo[3,2-f][1]benzopyran-2-carboxamide
32.08% activity remaining
7-(4-fluorophenyl)-1,7-dimethyl-9-oxo-N-propyl-8,9-dihydro-7H-furo[3,2-f][1]benzopyran-2-carboxamide
48.72% activity remaining
7-(4-fluorophenyl)-1,7-dimethyl-N-[3-(morpholin-4-yl)propyl]-9-oxo-8,9-dihydro-7H-furo[3,2-f][1]benzopyran-2-carboxamide
47.73% activity remaining
AMP
-
ADP/phosphate-exchange
Ap3A
-
ADP/phosphate-exchange
Ca2+
-
weak, NDP-arsenolysis or NDP/phosphate-exchange reaction
Cd2+
-
only NDP-arsenolysis or NDP/phosphate-exchange reaction
Co2+
-
weak, NDP-arsenolysis or NDP/phosphate-exchange reaction
dithioerythritol
-
-
ethyl 4-[2,5-bis(sulfanylidene)-4,5-dihydro[1,3]thiazolo[4',5':4,5]pyrimido[1,6-a]benzimidazol-3(2H)-yl]benzoate
42.80% activity remaining
methyl 3-[[2-(benzenesulfonyl)-2-cyano-1-(methylsulfanyl)ethyl]amino]benzoate
-
methylsulfanylacrylonitril
-
-
Mn2+
-
weak, NDP-arsenolysis or NDP/phosphate-exchange reaction
N-ethylmaleimide
-
-
p-hydroxymercuribenzoate
-
-
P1,P3-bis(5'-adenosyl) triphosphate with CCl2-bridge between P1 and P2
-
i.e. ApCCl2ppA
P1,P3-bis(5'-adenosyl) triphosphate with CHCl-bridge between P1 and P2
-
i.e. ApCHClppA
P1,P4-bis(5'-adenosyl) tetraphosphate
-
ADP/phosphate-exchange
[(5E)-5-[[2-(4-carbamoylpiperidin-1-yl)-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid
28.09% activity remaining
additional information
-