2.7.7.53: ATP adenylyltransferase
This is an abbreviated version!
For detailed information about ATP adenylyltransferase, go to the full flat file.
Reaction
+
=
+
Synonyms
5',5'''-P1,P4-tetraphosphate phosphorylase, adenine triphosphate adenylyltransferase, adenylyltransferase, adenine triphosphate, AP-4-A phosphorylase, Ap3A/Ap4A phosphorylase, Ap4A phosphorylase, bis(5'-nucleosyl)-tetraphosphate phosphorylase (NDP-forming), diadenosine 5',5'''-P1,P4-tetraphosphate alpha,beta-phosphorylase, diadenosine 5',5'''-P1,P4-tetraphosphate alpha,beta-phosphorylase (ADP-forming), diadenosine 5',5'''-P1,P4-tetraphosphate alphabeta-phosphorylase (ADP-forming), diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase, diadenosinetetraphosphate alpha,beta-phosphorylase, diadenosinetetraphosphate alphabeta-phosphorylase, dinucleoside oligophosphate alphabeta-phosphorylase, MAV_3489, MEG_2932, Rv2613c
ECTree
Metals Ions
Metals Ions on EC 2.7.7.53 - ATP adenylyltransferase
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Ca2+
-
activates
Ca2+
2 mM, 38% of the activity with Mn2+
Ca2+
Rv2613c requires bivalent metal ions such as Ca2+ to exert its Ap4A phosphorylase activity (64% activity in the presence of 2 mM Ca2+)
Ca2+
2 mM, 43% of the activity with Mn2+
Ca2+
-
less effective than Mg2+
Ca2+
-
requirement, less effective than Mn2+
Ca2+
-
less effective than Mg2+
Ca2+
-
less effective than Co2+
Cd2+
-
slight activation
Co2+
-
activates
Co2+
2 mM, 89% of the activity with Mn2+
Co2+
Rv2613c requires bivalent metal ions such as Co2+ to exert its Ap4A phosphorylase activity (68% activity in the presence of 2 mM Co2+)
Co2+
2 mM, 60% of the activity with Mn2+
Co2+
-
activation, less effective than Mn2+ or Ca2+ or Mg2+
Co2+
-
slight activation of P1,P4-bis(5'-adenosyl) tetraphosphate-synthesis
Co2+
-
activation, less effective than Mn2+ or Ca2+ or Mg2+
divalent metal cations
-
requirement
divalent metal cations
-
requirement
divalent metal cations
-
requirement
Mg2+
-
required, most effective divalent cation
Mg2+
2 mM, 98% of the activity with Mn2+
Mg2+
Rv2613c requires bivalent metal ions such as Mg2+ to exert its Ap4A phosphorylase activity (34% activity in the presence of 2 mM Mg2+)
Mg2+
2 mM, 97% of the activity with Mn2+
Mg2+
-
less effective than Mn2+ or Ca2+
Mg2+
-
inhibitory in presence of phosphate for ADP/phosphate exchange reaction
Mg2+
-
activation, P1,P4-bis(5'-adenosyl) tetraphosphate-synthesis
Mn2+
-
activates
Mn2+
2 mM, best divalent activator
Mn2+
Rv2613c requires bivalent metal ions such as Mn2+ to exert its Ap4A phosphorylase activity (100% activity in the presence of 2 mM Mn2+)
Mn2+
2 mM, best divalent activator
Mn2+
-
not NDP-arsenolysis or NDP/phosphate-exchange reaction
Mn2+
-
requirement, Ap4A-synthesis
Mn2+
-
less effective than Mg2+ or Co2+
Zn2+
-
slight activation
Zn2+
-
slight activation of P1,P4-bis(5'-adenosyl) tetraphosphate-synthesis
additional information
-
no divalent metal cation requirement for NDP-arsenolysis or NDP/phosphate-exchange reaction
additional information
-
no activation by Ni2+
additional information
-
no activation by Ni2+
additional information
-
Cu2+
additional information
-
no divalent metal cation requirement for NDP-arsenolysis or NDP/phosphate-exchange reaction