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2.7.7.B16: DNA primase

This is an abbreviated version!
For detailed information about DNA primase, go to the full flat file.

Word Map on EC 2.7.7.B16

Reaction

dNTP
+ n dNTP =
dN(pdN)n
+ n diphosphate

Synonyms

archaeal eukaryotic-type primase, DNA primase-polymerase, DnaG primase, Mjpri, Pabp41, Pabp46, pIT3 replication protein, PolpTN2, PriL, PriS, PriSL, PriX, Sso core primase, SsoPriSL

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.7 Nucleotidyltransferases
                2.7.7.B16 DNA primase

Reference

Reference on EC 2.7.7.B16 - DNA primase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Matsui, E.; Nishio, M.; Yokoyama, H.; Harata, K.; Darnis, S.; Matsui, I.
Distinct domain functions regulating de novo DNA synthesis of thermostable DNA primase from hyperthermophile Pyrococcus horikoshii
Biochemistry
42
14968-14976
2003
Pyrococcus horikoshii (O57934 and O57935), Pyrococcus horikoshii
Manually annotated by BRENDA team
Ito, N.; Matsui, I.; Matsui, E.
Molecular basis for the subunit assembly of the primase from an archaeon Pyrococcus horikoshii
FEBS J.
274
1340-1351
2007
Pyrococcus horikoshii (O57934 and O57935)
Manually annotated by BRENDA team
Prato, S.; Vitale, R.M.; Contursi, P.; Lipps, G.; Saviano, M.; Rossi, M.; Bartolucci, S.
Molecular modeling and functional characterization of the monomeric primase-polymerase domain from the Sulfolobus solfataricus plasmid pIT3
FEBS J.
275
4389-4402
2008
Saccharolobus solfataricus (Q9UWW1 and Q97Z83), Saccharolobus solfataricus, Saccharolobus solfataricus P2 (Q9UWW1 and Q97Z83)
Manually annotated by BRENDA team
Ito, N.; Nureki, O.; Shirouzu, M.; Yokoyama, S.; Hanaoka, F.
Crystal structure of the Pyrococcus horikoshii DNA primase-UTP complex: implications for the mechanism of primer synthesis
Genes Cells
8
913-923
2003
Pyrococcus horikoshii (O57934 and O57935), Pyrococcus horikoshii
Manually annotated by BRENDA team
Ito, N.; Nureki, O.; Shirouzu, M.; Yokoyama, S.; Hanaoka, F.
Crystallization and preliminary X-ray analysis of a DNA primase from hyperthermophilic archaeon Pyrococcus horikoshii
J. Biochem.
130
727-730
2001
Pyrococcus horikoshii (O57934 and O57935), Pyrococcus horikoshii
Manually annotated by BRENDA team
Liu, L.; Komori, K.; Ishino, S.; Bocquier, A.A.; Cann, I.K.; Kohda, D.; Ishino, Y.
The archaeal DNA primase: biochemical characterization of the p41-p46 complex from Pyrococcus furiosus
J. Biol. Chem.
276
45484-45490
2001
Pyrococcus furiosus (Q9P9H1 and Q8U4H7), Pyrococcus furiosus
Manually annotated by BRENDA team
Chemnitz Galal, W.; Pan, M.; Kelman, Z.; Hurwitz, J.
Characterization of DNA primase complex isolated from the archaeon, Thermococcus kodakaraensis
J. Biol. Chem.
287
16209-16219
2012
Thermococcus kodakarensis (Q5JJ72 and Q5JJ73), Thermococcus kodakarensis
Manually annotated by BRENDA team
Chemnitz Galal, W.; Pan, M.; Giulian, G.; Yuan, W.; Li, S.; Edwards, J.L.; Marino, J.P.; Kelman, Z.; Hurwitz, J.
Formation of dAMP-glycerol and dAMP-Tris derivatives by Thermococcus kodakaraensis DNA primase
J. Biol. Chem.
287
16220-16229
2012
Thermococcus kodakarensis (Q5JJ72 and Q5JJ73), Thermococcus kodakarensis
Manually annotated by BRENDA team
Lao-Sirieix, S.H.; Bell, S.D.
The heterodimeric primase of the hyperthermophilic archaeon Sulfolobus solfataricus possesses DNA and RNA primase, polymerase and 3-terminal nucleotidyl transferase activities
J. Mol. Biol.
344
1251-1263
2004
Saccharolobus solfataricus (Q9UWW1 and Q97Z83), Saccharolobus solfataricus, Saccharolobus solfataricus P2 (Q9UWW1 and Q97Z83)
Manually annotated by BRENDA team
Le Breton, M.; Henneke, G.; Norais, C.; Flament, D.; Myllykallio, H.; Querellou, J.; Raffin, J.P.
The heterodimeric primase from the euryarchaeon Pyrococcus abyssi: a multifunctional enzyme for initiation and repair?
J. Mol. Biol.
374
1172-1185
2007
Pyrococcus abyssi (Q9V292 and Q9V291), Pyrococcus abyssi
Manually annotated by BRENDA team
Wu, K.; Lai, X.; Guo, X.; Hu, J.; Xiang, X.; Huang, L.
Interplay between primase and replication factor C in the hyperthermophilic archaeon Sulfolobus solfataricus
Mol. Microbiol.
63
826-837
2006
Saccharolobus solfataricus (Q9UWW1 and Q97Z83), Saccharolobus solfataricus P2 (Q9UWW1 and Q97Z83)
Manually annotated by BRENDA team
Augustin, M.A.; Huber, R.; Kaiser, J.T.
Crystal structure of a DNA-dependent RNA polymerase (DNA primase)
Nat. Struct. Biol.
8
57-61
2001
Pyrococcus furiosus (Q9P9H1 and Q8U4H7)
Manually annotated by BRENDA team
Lao-Sirieix, S.H.; Nookala, R.K.; Roversi, P.; Bell, S.D.; Pellegrini, L.
Structure of the heterodimeric core primase
Nat. Struct. Mol. Biol.
12
1137-1144
2005
Saccharolobus solfataricus (Q9UWW1 and Q97Z83), Saccharolobus solfataricus P2 (Q9UWW1 and Q97Z83)
Manually annotated by BRENDA team
Desogus, G.; Onesti, S.; Brick, P.; Rossi, M.; Pisani, F.M.
Identification and characterization of a DNA primase from the hyperthermophilic archaeon Methanococcus jannaschii
Nucleic Acids Res.
27
4444-4450
1999
Methanocaldococcus jannaschii (Q58249), Methanocaldococcus jannaschii, Methanocaldococcus jannaschii JAL-1 (Q58249)
Manually annotated by BRENDA team
De Falco, M.; Fusco, A.; De Felice, M.; Rossi, M.; Pisani, F.M.
The DNA primase of Sulfolobus solfataricus is activated by substrates containing a thymine-rich bubble and has a 3'-terminal nucleotidyl-transferase activity
Nucleic Acids Res.
32
5223-5230
2004
Saccharolobus solfataricus (Q9UWW1 and Q97Z83), Saccharolobus solfataricus, Saccharolobus solfataricus P2 (Q9UWW1 and Q97Z83)
Manually annotated by BRENDA team
Hu, J.; Guo, L.; Wu, K.; Liu, B.; Lang, S.; Huang, L.
Template-dependent polymerization across discontinuous templates by the heterodimeric primase from the hyperthermophilic archaeon Sulfolobus solfataricus
Nucleic Acids Res.
40
3470-3483
2012
Saccharolobus solfataricus (Q9UWW1 and Q97Z83), Saccharolobus solfataricus, Saccharolobus solfataricus P2 (Q9UWW1 and Q97Z83)
Manually annotated by BRENDA team
Bauer, R.J.; Graham, B.W.; Trakselis, M.A.
Novel interaction of the bacterial-like DnaG primase with the MCM helicase in archaea
J. Mol. Biol.
425
1259-1273
2013
Saccharolobus solfataricus
Manually annotated by BRENDA team
Lipps, G.; Weinzierl, A.O.; von Scheven, G.; Buchen, C.; Cramer, P.
Structure of a bifunctional DNA primase-polymerase
Nat. Struct. Mol. Biol.
11
157-162
2004
Sulfolobus islandicus
Manually annotated by BRENDA team
Beguin, P.; Gill, S.; Charpin, N.; Forterre, P.
Synergistic template-free synthesis of dsDNA by Thermococcus nautili primase PolpTN2, DNA polymerase PolB, and pTN2 helicase
Extremophiles
19
69-76
2015
Thermococcus nautili
Manually annotated by BRENDA team
Liu, B.; Ouyang, S.; Makarova, K.S.; Xia, Q.; Zhu, Y.; Li, Z.; Guo, L.; Koonin, E.V.; Liu, Z.J.; Huang, L.
A primase subunit essential for efficient primer synthesis by an archaeal eukaryotic-type primase
Nat. Commun.
6
7300
2015
Saccharolobus solfataricus (Q9UWW1 AND Q97Z83 AND Q97ZS7), Saccharolobus solfataricus
Manually annotated by BRENDA team