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Disease on EC 1.1.1.40 - malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Adenocarcinoma
Arginine Methylation of MDH1 by CARM1 Inhibits Glutamine Metabolism and Suppresses Pancreatic Cancer.
[Oxidoreductase activity in the cells of stomach cancer]
Breast Neoplasms
Identification of genes with altered expression in medullary breast cancer vs. ductal breast cancer and normal breast epithelia.
Malic Enzyme 1 Indicates Worse Prognosis in Breast Cancer and Promotes Metastasis by Manipulating Reactive Oxygen Species.
Carcinogenesis
MicroRNA-30a attenuates mutant KRAS-driven colorectal tumorigenesis via direct suppression of ME1.
Carcinoma
Down-regulation of malic enzyme 1 and 2: Sensitizing head and neck squamous cell carcinoma cells to therapy-induced senescence.
Malic Enzyme 1 Is Associated with Tumor Budding in Oral Squamous Cell Carcinomas.
Carcinoma, Hepatocellular
Hydroperoxide-stimulated release of calcium from rat liver and AS-30D hepatoma mitochondria.
Malic enzyme 1 induces epithelial-mesenchymal transition and indicates poor prognosis in hepatocellular carcinoma.
Proportional activities of glycerol kinase and glycerol 3-phosphate dehydrogenase in rat hepatomas.
Carcinoma, Non-Small-Cell Lung
Mutant KRAS associated malic enzyme 1 expression is a predictive marker for radiation therapy response in non-small cell lung cancer.
Carcinoma, Squamous Cell
Down-regulation of malic enzyme 1 and 2: Sensitizing head and neck squamous cell carcinoma cells to therapy-induced senescence.
Cholangiocarcinoma
Malic enzyme 1 is a potential marker of combined hepatocellular cholangiocarcinoma, subtype with stem-cell features, intermediate-cell type.
Colonic Neoplasms
The HMGB1 protein induces a metabolic type of tumour cell death by blocking aerobic respiration.
Dehydration
Implications of terminal oxidase function in regulation of salicylic acid on soybean seedling photosynthetic performance under water stress.
Induced expression of the gene for NADP-malic enzyme in leaves of Aloe vera L. under salt stress.
Photosynthetic and anatomical characteristics in the C4crassulacean acid metabolism-cycling plant Portulaca grandiflora.
The activities of PEP carboxylase and the C(4) acid decarboxylases are little changed by drought stress in three C(4) grasses of different subtypes.
Diabetes Mellitus, Experimental
[Activity of NAD- and NADP-dependent malate dehydrogenase isoenzymes in the myocardium of rabbits with alloxan diabetes]
[Antagonism in the action of hydrocortisone and insulin in vivo on enzymes of pyruvate and malate metabolism in adipose tissue]
Dwarfism
Plastidial NAD-dependent malate dehydrogenase is critical for embryo development and heterotrophic metabolism in Arabidopsis.
Friedreich Ataxia
Skeletal muscle NAD+(P) and NADP+-dependent malic enzyme in Friedreich's ataxia.
Hypertriglyceridemia
Regulation of gene expression and activity of malic enzyme in liver of hereditary hypertriglyceridemic (hHTG) insulin resistant rat: effect of dietary sucrose and marine fish oil.
Hypokinesia
[Oxidative enzyme activity of the tricarboxylic acid cycle in rat skeletal muscles in hypokinesia]
Hypothyroidism
Changes of activity and kinetics of certain liver and heart enzymes of hypothyroid and T(3)-treated rats.
Infections
Activities of key enzymes in the C4 pathway and anatomy of sugarcane infected by Leifsoniaxyli subsp. xyli.
Iron- and Reactive Oxygen Species-Dependent Ferroptotic Cell Death in Rice-Magnaporthe oryzae Interactions.
Loss of cytosolic NADP-malic enzyme 2 in Arabidopsis thaliana is associated with enhanced susceptibility to Colletotrichum higginsianum.
Intestinal Volvulus
Inhibition of NADP-linked malic enzyme from Onchocerca volvulus and Dirofilaria immitis by suramin.
Lung Neoplasms
Mutant KRAS associated malic enzyme 1 expression is a predictive marker for radiation therapy response in non-small cell lung cancer.
malate dehydrogenase deficiency
Plastidial NAD-dependent malate dehydrogenase is critical for embryo development and heterotrophic metabolism in Arabidopsis.
Melanoma
Gene Expression Profiles of Adult Peripheral and Cord Blood Mononuclear Cells Altered by Lipopolysaccharide.
Nasopharyngeal Carcinoma
Repressing malic enzyme 1 redirects glucose metabolism, unbalances the redox state, and attenuates migratory and invasive abilities in nasopharyngeal carcinoma cell lines.
Neoplasm Metastasis
Malic Enzyme 1 Indicates Worse Prognosis in Breast Cancer and Promotes Metastasis by Manipulating Reactive Oxygen Species.
miR-885-5p Inhibits Invasion and Metastasis in Gastric Cancer by Targeting Malic Enzyme 1.
Neoplasms
Caffeic Acid Targets AMPK Signaling and Regulates Tricarboxylic Acid Cycle Anaplerosis while Metformin Downregulates HIF-1?-Induced Glycolytic Enzymes in Human Cervical Squamous Cell Carcinoma Lines.
Dynamic Description of the Catalytic Cycle of Malate Enzyme?Stereoselective Recognition of Substrate, Chemical Reaction and Ligand Release.
Effects of ME3 on the proliferation, invasion and metastasis of pancreatic cancer cells through epithelial-mesenchymal transition.
Gene Expression Profiles of Adult Peripheral and Cord Blood Mononuclear Cells Altered by Lipopolysaccharide.
Human NAD(+)-dependent mitochondrial malic enzyme. cDNA cloning, primary structure, and expression in Escherichia coli.
Inhibition of malic enzyme 1 disrupts cellular metabolism and leads to vulnerability in cancer cells in glucose-restricted conditions.
Interleukin-12 administration is more effective for preventing metastasis than for inhibiting primary established tumors in a murine model of spontaneous hepatic metastasis.
Malic enzyme 1 (ME1) in the biology of cancer: it is not just intermediary metabolism.
Malic enzyme 1 (ME1) is a potential oncogene in gastric cancer cells and is associated with poor survival of gastric cancer patients.
Malic Enzyme 1 Is Associated with Tumor Budding in Oral Squamous Cell Carcinomas.
Metformin and caffeic acid regulate metabolic reprogramming in human cervical carcinoma SiHa/HTB-35 cells and augment anticancer activity of Cisplatin via cell cycle regulation.
Mutant KRAS associated malic enzyme 1 expression is a predictive marker for radiation therapy response in non-small cell lung cancer.
[Oxidoreductase activity in the cells of stomach cancer]
Obesity
[Obesity, malic enzyme and aging--an animal experiment study]
Pancreatic Neoplasms
Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma.
Squamous Cell Carcinoma of Head and Neck
Down-regulation of malic enzyme 1 and 2: Sensitizing head and neck squamous cell carcinoma cells to therapy-induced senescence.
Malic Enzyme 1 Is Associated with Tumor Budding in Oral Squamous Cell Carcinomas.
Starvation
The effect of starvation and refeeding on lipogenic enzymes in mammary glands and livers of lactating rats.
Stomach Neoplasms
Malic enzyme 1 (ME1) is a potential oncogene in gastric cancer cells and is associated with poor survival of gastric cancer patients.
miR-885-5p Inhibits Invasion and Metastasis in Gastric Cancer by Targeting Malic Enzyme 1.
Thiamine Deficiency
Lipogenesis in the brain of thiamine-deficient rat pups.
Urinary Bladder Neoplasms
Tumor-suppressing effects of microRNA-612 in bladder cancer cells by targeting malic enzyme 1 expression.
Virus Diseases
Effect of Potato Virus Y on the NADP-Malic Enzyme from Nicotiana tabacum L.: mRNA, Expressed Protein and Activity.