Information on EC 1.1.1.400 - 2-methyl-1,2-propanediol dehydrogenase

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The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
1.1.1.400
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RECOMMENDED NAME
GeneOntology No.
2-methyl-1,2-propanediol dehydrogenase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2-methylpropane-1,2-diol + NAD+ = 2-hydroxy-2-methylpropanal + NADH + H+
show the reaction diagram
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
2-methylpropene degradation
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methyl tert-butyl ether degradation
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SYSTEMATIC NAME
IUBMB Comments
2-methylpropane-1,2-diol:NAD+ 1-oxidoreductase
This bacterial enzyme is involved in the degradation pathways of the alkene 2-methylpropene and the fuel additive tert-butyl methyl ether (MTBE), a widely occurring groundwater contaminant.