Information on EC 1.1.99.26 - 3-hydroxycyclohexanone dehydrogenase

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The expected taxonomic range for this enzyme is: Pseudomonas sp.

EC NUMBER
COMMENTARY hide
1.1.99.26
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RECOMMENDED NAME
GeneOntology No.
3-hydroxycyclohexanone dehydrogenase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
3-hydroxycyclohexanone + acceptor = cyclohexane-1,3-dione + reduced acceptor
show the reaction diagram
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-
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-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
oxidation
-
-
-
-
redox reaction
-
-
-
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reduction
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-
-
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SYSTEMATIC NAME
IUBMB Comments
3-hydroxycyclohexanone:acceptor 1-oxidoreductase
2,6-Dichloroindophenol and methylene blue can act as acceptors.
CAS REGISTRY NUMBER
COMMENTARY hide
123516-44-9
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
enzyme is induced by growth on cyclohexanone under anaerobic conditions
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Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
3-hydroxycyclohexanone + acceptor
1,3-cyclohexanedione + reduced acceptor
show the reaction diagram
-
methylene blue or 2,6-dichlorophenolindophenol can function as electron acceptor in vitro
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?
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.27
-
2-cyclohexenone hydratase and 3-hydroxycyclohexanone dehydrogenase activity in cell extracts
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
7.8
-
assay at
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
30
-
assay at
STORAGE STABILITY
ORGANISM
UNIPROT
LITERATURE
-20°C, cell extract stable for several days
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Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE