Information on EC 1.1.99.B7 - menaquinol-acceptor oxidoreductase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Specify your search results
Select one or more organisms in this record:
Show additional data
Do not include text mining results
Include (text mining) results (more...)
Include results (AMENDA + additional results, but less precise; more...)


The expected taxonomic range for this enzyme is: Archaeoglobus fulgidus

EC NUMBER
COMMENTARY hide
1.1.99.B7
preliminary BRENDA-supplied EC number
RECOMMENDED NAME
GeneOntology No.
menaquinol-acceptor oxidoreductase
-
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a quinol + acceptor = a quinone + reduced acceptor
show the reaction diagram
-
-
-
-
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
methanogenesis from CO2
-
-
SYSTEMATIC NAME
IUBMB Comments
quinol:acceptor oxidoreductase
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
O29751: extracytoplasmic iron-sulfur protein 1 (Hme subunit A), O29749: Hdr-like menaquinol oxidoreductase cytochrome b-like subunit (Hme subunit C), O29748: Hdr-like menaquinol oxidoreductase iron-sulfur subunit 2 (Hme subunit D), O29747: Hdr-like menaquinol oxidoreductase cytochrome c subunit (Hme subunit E)
O29751 and O29749 and O29748 and O29747
-
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
O29751 and O29749 and O29748 and O29747
the enzyme plays a key role in the energy metabolism of methanogenic archaea
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2,3-dimethyl-1,4-naphthoquinone + reduced coenzyme F420
2,3-dimethyl-1,4-naphthoquinol + oxidized coenzyme F420
show the reaction diagram
O29751 and O29749 and O29748 and O29747
-
-
-
?
additional information
?
-
O29751 and O29749 and O29748 and O29747
the enzyme plays a key role in the energy metabolism of methanogenic archaea
-
-
-
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
additional information
?
-
O29751 and O29749 and O29748 and O29747
the enzyme plays a key role in the energy metabolism of methanogenic archaea
-
-
-
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
heme
O29751 and O29749 and O29748 and O29747
heme/iron-sulfur protein. The heme groups of the enzyme are rapidly reduced by reduced 2,3-dimethyl-1,4-naphthoquinone, which indicates that the enzyme functions as a menaquinol-acceptor oxidoreductase
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Iron-sulfur cluster
O29751 and O29749 and O29748 and O29747
contains [4Fe-4S]+ clusters
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
O29751 and O29749 and O29748 and O29747
membrane-bound enzyme complex
Manually annotated by BRENDA team
SUBUNITS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
oligomer
O29751 and O29749 and O29748 and O29747
x * 64400 (Hme subunit D) + x * 38000 (Hme subunit C) + x * 30500 (Hme subunit A) + x * 16700 (Hme subunit E), SDS-PAGE
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
-
O29751 and O29749 and O29748 and O29747