Information on EC 1.10.1.1 - trans-acenaphthene-1,2-diol dehydrogenase

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The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
1.10.1.1
-
RECOMMENDED NAME
GeneOntology No.
trans-acenaphthene-1,2-diol dehydrogenase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(+/-)-trans-acenaphthene-1,2-diol + 2 NADP+ = acenaphthenequinone + 2 NADPH + 2 H+
show the reaction diagram
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
oxidation
-
-
-
-
redox reaction
-
-
-
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reduction
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-
-
-
SYSTEMATIC NAME
IUBMB Comments
(+/-)-trans-acenaphthene-1,2-diol:NADP+ oxidoreductase
Some preparations also utilize NAD+.
CAS REGISTRY NUMBER
COMMENTARY hide
51901-21-4
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
-
-
Manually annotated by BRENDA team
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-
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Manually annotated by BRENDA team
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-
-
Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(-)-trans-acenaphthene-1,2-diol + NADP+
acenaphthenequinone + NADPH
show the reaction diagram
1-acenaphthenol + NADP+
1-acenaphthenone + NADPH
show the reaction diagram
trans-1,2-dihydronaphthalene-1,2-diol + NADP+
1,2-naphthoquinone + NADPH
show the reaction diagram
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
(-)-trans-acenaphthene-1,2-diol + NADP+
acenaphthenequinone + NADPH
show the reaction diagram
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
NADP+
-
inactive with NAD+
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Mg2+
-
activation
INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
(+)-trans-Acenaphthene-1,2-diol
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-
2,4-Dichlorophenol
-
75% inhibition at 1 mM
catechol
-
75% inhibition at 1 mM
Hg2+
-
100% inhibition at 0.1 mM
KCN
-
70% inhibition at 5 mM
p-chloromercuribenzoate
-
100% inhibition at 0.25 mM
ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
ethanol
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activation
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE