Information on EC 1.11.1.B7 - bromide peroxidase (heme-containing)

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The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
1.11.1.B7
preliminary BRENDA-supplied EC number
RECOMMENDED NAME
GeneOntology No.
bromide peroxidase (heme-containing)
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
RH + HBr + H2O2 = RBr + 2 H2O
show the reaction diagram
Brings about the bromination of a range of organic molecules, forming stable C-Br bonds. Contains heme.
-
-
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SYSTEMATIC NAME
IUBMB Comments
bromide:hydrogen-peroxide oxidoreductase (heme-containing)
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
EF group 70B
-
-
Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
Br- + H2O2 + 1,1-dimethyl-4-chloro-3,5-cyclohexanedione
?
show the reaction diagram
Br- + H2O2 + 3-chloro-4-(2-nitro-3-chlorophenyl)pyrrole
2-bromo-3-chloro-4-(2-nitro-3-chlorophenyl)pyrrole + ?
show the reaction diagram
Br- + H2O2 + dianisidine
?
show the reaction diagram
-
-
-
-
?
Br- + H2O2 + monochlorodimedone
?
show the reaction diagram
additional information
?
-
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
azide
-
75 mM, 50% inhibition
cyanide
-
0.023 mM, 50% inhibition
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
7
-
catalase activity
pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
5 - 7
-
totally inactive at pGH 4.5, pH optimum at pH 5.0, 30% of maximal activity at pH 7.0
pI VALUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
4
-
isoelectric focusing, pH-range 3.5-9.5
4.7
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isoelectric focusing, pH-range 2.5-6.5
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
147000
-
gel filtration
153000
-
gel filtration
SUBUNITS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
pH STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
4 - 12
-
30 min, stable
673375
TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
55
-
30 min, stable
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE