Information on EC 1.13.11.70 - all-trans-10'-apo-beta-carotenal 13,14-cleaving dioxygenase

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The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
1.13.11.70
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RECOMMENDED NAME
GeneOntology No.
all-trans-10'-apo-beta-carotenal 13,14-cleaving dioxygenase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
all-trans-10'-apo-beta-carotenal + O2 = 13-apo-beta-carotenone + (2E,4E,6E)-4-methylocta-2,4,6-trienedial
show the reaction diagram
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
carotenoid cleavage
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SYSTEMATIC NAME
IUBMB Comments
all-trans-10'-apo-beta-carotenal:O2 oxidoreductase (13,14-cleaving)
Requires Fe2+. The enzyme from the plant Arabidopsis thaliana also catalyses EC 1.13.11.69, carlactone synthase, 10-fold faster.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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UniProt
Manually annotated by BRENDA team
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Manually annotated by BRENDA team
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UniProt
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
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using a PpCCD8 knockout mutant, it is shown that PpCCD8 is involved in strigolactone biosynthesis and regulates the branching of filament and colony extension. In wild-type Physcomitrella patens, secreted strigolactones are directly involved in the regulation of colony extension in response to internal cues or population density
physiological function
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
all-trans-10'-apo-beta-carotenal + O2
13-apo-beta-carotenone + (2E,4E,6E)-4-methylocta-2,4,6-trienedial
show the reaction diagram
all-trans-10'-apo-beta-carotenal + O2
13-apo-beta-carotenone + ?
show the reaction diagram
all-trans-10'-apo-beta-carotenol + O2
13-apo-beta-carotenone + ?
show the reaction diagram
additional information
?
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INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
additional information
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no evidence for feedback regulation
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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
additional information
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expression of gene is widely distributed, but at low level
Manually annotated by BRENDA team
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
expression in Escherichia coli
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
enzyme is upregulated in the root eleongation zone following 24 h auxin treatment, and hypocotyl, and this is not required for the inhibition of shoot branching
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expression is induced by auxin
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gene is repressed by low phosphate stress
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no evidence is found for auxin-induced upregulation of enzyme expression in nodal tissue
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ENGINEERING
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information