Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
dinoflagellate luciferin + O2
?
dinoflagellate luciferin + O2
oxidized dinoflagellate luciferin + H2O + hnu
-
-
-
-
?
dinoflagellate luciferin + O2
oxidized dinoflagellate luciferin + H2O + hv
additional information
?
-
each of the three domains of Lingulodinium polyedrum luciferase encodes an active luciferase that catalyzes the oxidation of a chlorophyll-derived open tetrapyrrole (dinoflagellate luciferin) to produce blue light
-
-
?
dinoflagellate luciferin + O2
?
-
-
-
-
?
dinoflagellate luciferin + O2
?
-
-
-
-
?
dinoflagellate luciferin + O2
oxidized dinoflagellate luciferin + H2O + hv
-
-
-
-
?
dinoflagellate luciferin + O2
oxidized dinoflagellate luciferin + H2O + hv
-
-
-
-
ir
dinoflagellate luciferin + O2
oxidized dinoflagellate luciferin + H2O + hv
-
-
-
?
dinoflagellate luciferin + O2
oxidized dinoflagellate luciferin + H2O + hv
-
-
-
-
?
dinoflagellate luciferin + O2
oxidized dinoflagellate luciferin + H2O + hv
-
-
-
-
?
dinoflagellate luciferin + O2
oxidized dinoflagellate luciferin + H2O + hv
-
-
-
?
dinoflagellate luciferin + O2
oxidized dinoflagellate luciferin + H2O + hv
-
-
-
-
?
dinoflagellate luciferin + O2
oxidized dinoflagellate luciferin + H2O + hv
-
-
-
-
?
dinoflagellate luciferin + O2
oxidized dinoflagellate luciferin + H2O + hv
-
-
-
-
?
dinoflagellate luciferin + O2
oxidized dinoflagellate luciferin + H2O + hv
-
-
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Ag+
-
-
chlorotetracycline
-
-
Co2+
-
-
Cu2+
-
inhibits the light emission by dinoflagellate luciferase
Cu2+
-
inhibits the light emission by dinoflagellate luciferase
Cu2+
-
inhibits the light emission by dinoflagellate luciferase
cyanide
-
-
EDTA
-
-
EGTA
-
-
Fe2+
-
inhibits the light emission by dinoflagellate luciferase
Fe2+
-
inhibits the light emission by dinoflagellate luciferase
Fe2+
-
inhibits the light emission by dinoflagellate luciferase
Fe3+
-
inhibits the light emission by dinoflagellate luciferase
Fe3+
-
inhibits the light emission by dinoflagellate luciferase
Fe3+
-
inhibits the light emission by dinoflagellate luciferase
Hg2+
-
-
Ni2+
-
inhibits the light emission by dinoflagellate luciferase
Ni2+
-
inhibits the light emission by dinoflagellate luciferase
Ni2+
-
inhibits the light emission by dinoflagellate luciferase
Pb2+
-
-
Sodium azide
-
-
Sr2+
-
-
Zn2+
-
inhibits the light emission by dinoflagellate luciferase
Zn2+
-
inhibits the light emission by dinoflagellate luciferase
Zn2+
-
inhibits the light emission by dinoflagellate luciferase
additional information
-
after a 15 min incubation at pH 8.0 and 20°C with subtilisin, trypsin, chymotrypsin, pepsin, carboxypeptidase, and leucine aminopeptidase, the flash height measured in the presence of saturating luciferin is 50% lowered and, after 1 h, the flash height is 10% of the control. Moreover, proteolysis of the extracts completely inactivates the luciferase
-
additional information
-
after a 15 min incubation at pH 8.0 and 20°C with subtilisin, trypsin, chymotrypsin, pepsin, carboxypeptidase, and leucine aminopeptidase, the flash height measured in the presence of saturating luciferin is 50% lowered and, after 1 h, the flash height is 10% of the control. Moreover, proteolysis of the extracts completely inactivates the luciferase
-
additional information
-
after a 15 min incubation at pH 8.0 and 20°C with subtilisin, trypsin, chymotrypsin, pepsin, carboxypeptidase, and leucine aminopeptidase, the flash height measured in the presence of saturating luciferin is 50% lowered and, after 1 h, the flash height is 10% of the control. Moreover, proteolysis of the extracts completely inactivates the luciferase
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Liu, L.; Im, H.; Cegielski, M.; LeMagueres, P.; Schultz, L.W.; Krause, K.L.; Hastings, J.W.
Characterization and crystallization of active domains of a novel luciferase from a marine dinoflagellate
Acta Crystallogr. Sect. D
59
761-764
2003
Lingulodinium polyedra
brenda
Lecuyer, B.; Arrio, B.; Fresneau, C.; Volfin, P.
Dinoflagellate luciferases: purification of luciferases from Gonyaulax polyedra, Pyrocystis lunula, and Pyrocystis fusiformis
Arch. Biochem. Biophys.
196
371-384
1979
Lingulodinium polyedra, Pyrocystis lunula, Pyrocystis fusiformis
brenda
Li, L.; Liu, L.; Hong, R.; Robertson, D.; Hastings, J.W.
N-terminal intramolecularly conserved histidines of three domains in Gonyaulax luciferase are responsible for loss of activity in the alkaline region
Biochemistry
40
1844-1849
2001
Lingulodinium polyedra
brenda
Bae, Y.M.; Hastings, J.W.
Cloning, sequencing and expression of dinoflagellate luciferase DNA from a marine alga, Gonyaulax polyedra
Biochim. Biophys. Acta
1219
449-456
1994
Lingulodinium polyedra (O77206), Lingulodinium polyedra, Lingulodinium polyedra GP70 (O77206)
brenda
Suzuki, C.; Nakajima, Y.; Akimoto, H.; Wu, C.; Ohmiya, Y.
A new additional reporter enzyme, dinoflagellate luciferase, for monitoring of gene expression in mammalian cells
Gene
344
61-66
2005
Pyrocystis lunula
brenda
Dunlap, J.C.; Hastings, J.W.
The biological clock in Gonyaulax controls luciferase activity by regulating turnover
J. Biol. Chem.
256
10509-10518
1981
Lingulodinium polyedra, Lingulodinium polyedra 70
brenda
Morse, D.; Pappenheimer, A.M., Jr.; Hastings, J.W.
Role of a luciferin-binding protein in the circadian bioluminescent reaction of Gonyaulax polyedra
J. Biol. Chem.
264
11822-11826
1989
Lingulodinium polyedra
brenda
Nicolas, M.T.; Nicolas, G.; Johnson, C.H.; Bassot, J.M.; Hastings, J.W.
Characterization of the bioluminescent organelles in Gonyaulax polyedra (dinoflagellates) after fast-freeze fixation and antiluciferase immunogold staining
J. Cell Biol.
105
723-735
1987
Lingulodinium polyedra, Lingulodinium polyedra 70
brenda
Nicolas, M.T.; Sweeney, B.M.; Hastings, J.W.
The ultrastructural localization of luciferase in three bioluminescent dinoflagellates, two species of Pyrocystis, and Noctiluca, using anti-luciferase and immunogold labelling
J. Cell Sci.
87
189-196
1987
no activity in Cachonina illdefina, Pyrocystis fusiformis, Pyrocystis noctiluca, Noctiluca scintillans
brenda
Li, L.
Gonyaulax luciferase: gene structure, protein expression, and purification from recombinant sources
Methods Enzymol.
305
249-258
2000
Lingulodinium polyedra
brenda
Morse, D.; Mittag, M.
Dinoflagellate luciferin-binding protein
Methods Enzymol.
305
258-276
2000
Lingulodinium polyedra
brenda
Suzuki-Ogoh, C.; Wu, C.; Ohmiya, Y.
C-terminal region of the active domain enhances enzymatic activity in dinoflagellate luciferase
Photochem. Photobiol. Sci.
7
208-211
2008
Lingulodinium polyedra
brenda
Liu, L.; Wilson, T.; Hastings, J.W.
Molecular evolution of dinoflagellate luciferases, enzymes with three catalytic domains in a single polypeptide
Proc. Natl. Acad. Sci. USA
101
16555-16560
2004
Lingulodinium polyedra
brenda
Schultz, L.W.; Liu, L.; Cegielski, M.; Hastings, J.W.
Crystal structure of a pH-regulated luciferase catalyzing the bioluminescent oxidation of an open tetrapyrrole
Proc. Natl. Acad. Sci. USA
102
1378-1383
2005
Lingulodinium polyedra (O77206)
brenda
Liu, L.; Hastings, J.W.
Two different domains of the luciferase gene in the heterotrophic dinoflagellate Noctiluca scintillans occur as two separate genes in photosynthetic species
Proc. Natl. Acad. Sci. USA
104
696-701
2007
Noctiluca scintillans
brenda
Valiadi, M.; Painter, S.C.; Allen, J.T.; Balch, W.M.; Iglesias-Rodriguez, M.D.
Molecular detection of bioluminescent dinoflagellates in surface waters of the Patagonian shelf during early austral summer 2008
PLoS ONE
9
e98849
2014
uncultured dinoflagellate
brenda
Donnan, P.; Ngo, P.; Mansoorabadi, S.
Constant pH accelerated molecular dynamics investigation of the pH regulation mechanism of Dinoflagellate luciferase
Biochemistry
57
295-299
2018
Lingulodinium polyedra (O77206)
brenda
Kamerlin, N.; Delcey, M.G.; Lindh, R.
Unravelling the mechanism of pH-regulation in dinoflagellate luciferase
Int. J. Biol. Macromol.
164
2671-2680
2020
Lingulodinium polyedra (O77206), Lingulodinium polyedra
brenda