Information on EC 1.14.13.216 - asperlicin C monooxygenase

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The expected taxonomic range for this enzyme is: Aspergillus alliaceus

EC NUMBER
COMMENTARY hide
1.14.13.216
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RECOMMENDED NAME
GeneOntology No.
asperlicin C monooxygenase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
asperlicin C + NAD(P)H + H+ + O2 = asperlicin E + NAD(P)+ + H2O
show the reaction diagram
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
asperlicin E biosynthesis
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SYSTEMATIC NAME
IUBMB Comments
asperlicin C,NAD(P)H:oxygen oxidoreductase
The enzyme, characterized from the fungus Aspergillus alliaceus, contains an FAD cofactor. The enzyme inserts a hydroxyl group, leading to formation of a N-C bond that creates an additional cycle between the bicyclic indole and the tetracyclic core moieties, resulting in the heptacyclic asperlicin E.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
gene aspB
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Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
evolution
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
asperlicin C + FADH2 + O2
asperlicin E + FAD + H2O
show the reaction diagram
additional information
?
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NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
asperlicin C + FADH2 + O2
asperlicin E + FAD + H2O
show the reaction diagram
additional information
?
-
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
FAD
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FAD binding enzyme
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
gene aspB, recombinant expression in Escherichia coli
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