Information on EC 1.14.99.35 - thiophene-2-carbonyl-CoA monooxygenase

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The expected taxonomic range for this enzyme is: Aquamicrobium defluvii

EC NUMBER
COMMENTARY hide
1.14.99.35
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RECOMMENDED NAME
GeneOntology No.
thiophene-2-carbonyl-CoA monooxygenase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
thiophene-2-carbonyl-CoA + AH2 + O2 = 5-hydroxythiophene-2-carbonyl-CoA + A + H2O
show the reaction diagram
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-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
oxidation
-
-
-
-
redox reaction
-
-
-
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reduction
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-
-
-
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
glycolipid desaturation
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SYSTEMATIC NAME
IUBMB Comments
thiophene-2-carbonyl-CoA, hydrogen-donor:oxygen oxidoreductase
A molybdenum enzyme. Highly specific for thiophene-2-carbonyl-CoA. Tetrazolium salts can act as electron acceptors.
CAS REGISTRY NUMBER
COMMENTARY hide
208540-44-7
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
gen. nov. sp. nov.
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-
Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
thiophene-2-carbonyl-CoA + AH2 + O2
5-hydroxythiophene-2-carbonyl-CoA + A + H2O
show the reaction diagram
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
thiophene-2-carbonyl-CoA + AH2 + O2
5-hydroxythiophene-2-carbonyl-CoA + A + H2O
show the reaction diagram
-
enzyme is involved in metabolism of thiophene 2-carboxylate
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-
?
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Molybdenum
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enzyme contains molybdenum
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
220000
-
gel filtration