Information on EC 1.14.99.44 - diapolycopene oxygenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Specify your search results
Select one or more organisms in this record:
Show additional data
Do not include text mining results
Include (text mining) results (more...)
Include results (AMENDA + additional results, but less precise; more...)

The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
1.14.99.44
-
RECOMMENDED NAME
GeneOntology No.
diapolycopene oxygenase
-
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
4,4'-diapolycopene + 4 AH2 + 4 O2 = 4,4'-diapolycopenedial + 4 A + 6 H2O
show the reaction diagram
-
-
-
-
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
4,4'-diapolycopenedioate biosynthesis
-
-
Carotenoid biosynthesis
-
-
SYSTEMATIC NAME
IUBMB Comments
4,4'-diapolycopene,AH2:oxygen oxidoreductase (4,4'-hydroxylating)
Little activity with neurosporene or lycopene. Involved in the biosynthesis of C30 carotenoids such as staphyloxanthin. The enzyme oxidizes each methyl group to the hydroxymethyl and then a dihydroxymethyl group, followed by the spontaneous loss of water to give an aldehyde group.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2,4,2',4'-tetradehydrolycopene + AH2 + O2
2,4,2',4'-tetradehydrolycopendial + A + H2O
show the reaction diagram
-
-
-
?
2,4,2',4'-tetradehydrolycopene + AH2 + O2
2,4,2',4'-tetradehydrolycopene dialdehyde + 2,4,2',4'-tetradehydrolycopene monoaldehyde + A + H2O
show the reaction diagram
4,4'-diapolycopene + AH2 + O2
4,4'-diapolycopen-4,4'-dial + A + H2O
show the reaction diagram
-
-
-
?
4,4'-diapolycopene + AH2 + O2
4,4'-diapolycopene-4,4'-dial + A + H2O
show the reaction diagram
4,4'-diapolycopene + AH2 + O2
4,4'-diapolycopene-4,4'-dialdehyde + A + H2O
show the reaction diagram
4,4'-diaponeurosporene + AH2 + O2
4,4'-diaponeurosporen-4-al + A + H2O
show the reaction diagram
4,4'-diaponeurosporene + AH2 + O2
4,4'-diaponeurosporen-4-monoaldehyde + A + H2O
show the reaction diagram
additional information
?
-
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
expressed in Escherichia coli
expressed in Escherichia coli BL21(DE3) cells
expressed in Escherichia coli JM109 cells