Information on EC 1.2.1.98 - 2-hydroxy-2-methylpropanal dehydrogenase

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The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
1.2.1.98
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RECOMMENDED NAME
GeneOntology No.
2-hydroxy-2-methylpropanal dehydrogenase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2-hydroxy-2-methylpropanal + NAD+ + H2O = 2-hydroxyisobutanoate + NADH + H+
show the reaction diagram
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
2-methylpropene degradation
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methyl tert-butyl ether degradation
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SYSTEMATIC NAME
IUBMB Comments
2-hydroxy-2-methylpropanal:NAD+ oxidoreductase
This bacterial enzyme is involved in the degradation pathways of the alkene 2-methylpropene and the fuel additive tert-butyl methyl ether (MTBE), a widely occurring groundwater contaminant.