We're sorry, but BRENDA doesn't work properly without JavaScript. Please make sure you have JavaScript enabled in your browser settings.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments A hemoprotein. This enzyme is an isoform of aldehyde oxidase (EC 1.2.3.1). It has a preference for aldehydes having an indole-ring structure as substrate [6,7]. It may play a role in plant hormone biosynthesis as its activity is higher in the auxin-overproducing mutant, super-root1 , than in wild-type Arabidopsis thaliana . While (indol-3-yl)acetaldehyde is the preferred substrate, it also oxidizes indole-3-carbaldehyde and acetaldehyde, but more slowly. The enzyme from maize contains FAD, iron and molybdenum .
The expected taxonomic range for this enzyme is: Eukaryota, Archaea
Synonyms
aogamma, indoleacetaldehyde oxidase, iaald oxidase, indole-3-acetaldehyde oxidase,
more
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
indoleacetaldehyde oxidase
-
-
-
-
oxidase, indoleacetaldehyde
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
(indol-3-yl)acetaldehyde + H2O + O2 = (indol-3-yl)acetate + H2O2
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
(indol-3-yl)acetaldehyde:oxygen oxidoreductase
A hemoprotein. This enzyme is an isoform of aldehyde oxidase (EC 1.2.3.1). It has a preference for aldehydes having an indole-ring structure as substrate [6,7]. It may play a role in plant hormone biosynthesis as its activity is higher in the auxin-overproducing mutant, super-root1 , than in wild-type Arabidopsis thaliana [7]. While (indol-3-yl)acetaldehyde is the preferred substrate, it also oxidizes indole-3-carbaldehyde and acetaldehyde, but more slowly. The enzyme from maize contains FAD, iron and molybdenum [4].
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
abscisic aldehyde + oxidized 2,6-dichloroindophenol + H2O
abscisic acid + reduced 2,6-dichloroindophenol
-
-
-
?
acetaldehyde + O2 + H2O
acetate + H2O2
benzaldehyde + oxidized 2,6-dichloroindophenol + H2O
benzoic acid + reduced 2,6-dichloroindophenol
weak substrate
-
-
?
heptaldehyde + oxidized 2,6-dichloroindophenol + H2O
heptanoic acid + reduced 2,6-dichloroindophenol
weak substrate
-
-
?
indole-3-acetaldehyde + O2
indole-3-acetate + H2O2
highly efficient conversion
-
-
?
indole-3-acetaldehyde + O2 + H2O
indole-3-acetate + H2O2
indole-3-acetaldehyde + oxidized 2,6-dichloroindophenol + H2O
indole-3-acetate + reduced 2,6-dichloroindophenol
efficient substrate
-
-
?
indole-3-acetaldehyde + phenazine methosulfate
indole-3-acetate + ?
-
-
-
-
?
indole-3-aldehyde + O2
3-carboxyindole + H2O
phenylacetaldehyde + O2
phenylacetate + H2O
-
86% of the activity with indole-3-acetaldehyde
-
-
?
additional information
?
-
in addition to the two-electron reduction of molecular oxygen, isoform AAO1 also catalyzes a one-electron transfer to molecular oxygen, leading to the formation of O2-. However, the production of O2 appears to be less efficient than the production of H2O2
-
-
?
acetaldehyde + O2 + H2O
acetate + H2O2
-
no activity
-
-
?
acetaldehyde + O2 + H2O
acetate + H2O2
-
42% of the activity with indole-3-acetaldehyde
-
-
?
indole-3-acetaldehyde + O2 + H2O
indole-3-acetate + H2O2
-
-
-
?
indole-3-acetaldehyde + O2 + H2O
indole-3-acetate + H2O2
-
enzyme form AO1 has a possible role in indole-3-acetic acid biosynthesis
-
-
?
indole-3-acetaldehyde + O2 + H2O
indole-3-acetate + H2O2
-
-
-
?
indole-3-acetaldehyde + O2 + H2O
indole-3-acetate + H2O2
-
terminal step in biogenesis of indole-3-acetic acid
-
-
?
indole-3-acetaldehyde + O2 + H2O
indole-3-acetate + H2O2
-
-
-
?
indole-3-acetaldehyde + O2 + H2O
indole-3-acetate + H2O2
-
-
-
?
indole-3-acetaldehyde + O2 + H2O
indole-3-acetate + H2O2
-
-
-
?
indole-3-aldehyde + O2
3-carboxyindole + H2O
-
88% of the activity with indole-3-acetaldehyde
-
-
?
indole-3-aldehyde + O2
3-carboxyindole + H2O
-
21% of the activity with indole-3-acetaldehyde
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
indole-3-acetaldehyde + O2
indole-3-acetate + H2O2
highly efficient conversion
-
-
?
indole-3-acetaldehyde + O2 + H2O
indole-3-acetate + H2O2
indole-3-acetaldehyde + O2 + H2O
indole-3-acetate + H2O2
-
enzyme form AO1 has a possible role in indole-3-acetic acid biosynthesis
-
-
?
indole-3-acetaldehyde + O2 + H2O
indole-3-acetate + H2O2
-
terminal step in biogenesis of indole-3-acetic acid
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
heme
-
contains a heme type iron component
flavin
-
no flavoprotein
flavin
-
metalloflavoprotein
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Iron
-
contains a heme type iron component
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
2,4-Dichlorophenoxyacetic acid
-
-
Dichlorophenoxyacetic acid
-
-
diphenylene iodonium
strong inhibitor
indole-3-acetic acid
-
feedback inhibition in vivo
KCN
complete inhibition at 20 mM after 1 h incubation at room temperature
p-hydroxymercuribenzoate
-
-
additional information
-
not: p-phenanthroline, diethyldithiocarbamate, xanthogenate, semicarbazide
-
cyanide
-
-
EDTA
-
-
iodoacetate
-
-
N-ethylmaleimide
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
2-mercaptoethanol
-
activates
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Migraine Disorders
An MMPI control study: Chinese migraineurs during frequent headache attack intervals.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
0.345 - 1.4
Indole-3-acetaldehyde
0.345
Indole-3-acetaldehyde
-
-
1.4
Indole-3-acetaldehyde
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
0.093
using heptaldehyde as substrate, pH 7.5, temperature not specified in the publication
0.11
using benzaldehyde as substrate, pH 7.5, temperature not specified in the publication
0.515
using abscisic aldehyde as substrate, pH 7.5, temperature not specified in the publication
0.558
using indole-3-carbaldehyde as substrate, pH 7.5, temperature not specified in the publication
additional information
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
2.9 - 5.5
-
about 50% of maximal activity at pH 2.9 and at pH 5.5
5.8 - 6.8
-
pH 5.8: about 40% of maximal activity, pH 6.8: about 25% of maximal activity, crude extract
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
50 - 80
-
50°C: about 50% of maximal activity, 80°C: about 70% of maximal activity
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-
-
-
brenda
-
-
-
brenda
-
-
-
brenda
-
-
-
brenda
-
UniProt
brenda
enzyme form AO1
-
-
brenda
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
brenda
-
activity is higher in sur1 mutant seddlings than in wild-type
brenda
-
-
brenda
-
-
brenda
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
ALDO1_ARATH
1368
0
149554
Swiss-Prot
other Location (Reliability: 2 )
ALDO1_MAIZE
1358
0
146683
Swiss-Prot
other Location (Reliability: 4 )
ALDO2_ARATH
1321
0
144580
Swiss-Prot
other Location (Reliability: 3 )
ALDO2_MAIZE
1349
0
145176
Swiss-Prot
other Location (Reliability: 4 )
ALDO3_ARATH
1332
0
146701
Swiss-Prot
other Location (Reliability: 1 )
ALDO4_ARATH
1337
0
147304
Swiss-Prot
other Location (Reliability: 3 )
F9VNL5_SULTO
Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
162
0
17932
TrEMBL
-
F9VNL6_SULTO
Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
283
0
31255
TrEMBL
-
A0A6C0T926_PROCL
507
0
56401
TrEMBL
other Location (Reliability: 2 )
F9VNL4_SULTO
Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
744
0
81947
TrEMBL
-
A0A7C9AF54_OPUST
298
0
33204
TrEMBL
other Location (Reliability: 2 )
A0A7C9AEP6_OPUST
141
0
15224
TrEMBL
Mitochondrion (Reliability: 4 )
A0A7C9EFF1_OPUST
221
0
24485
TrEMBL
Mitochondrion (Reliability: 4 )
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
6 - 9
-
4°C, 18 h, stable
390440
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
40
-
10 min, 41% loss of activity
additional information
-
activated by heating at 60°C, about 2 min
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
prolonged dialysis inactivates
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Ni-NTA agarose column chromatography, and Source 15Q colum chromatography
partial
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
expressed in Pichia pastoris
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Bower, P.J.; Brown, H.M.; Purves, W.K.
Cucumber seedlings indoleacetaldehyde oxidase
Plant Physiol.
61
107-110
1978
Cucumis sativus
brenda
Miyata, S.; Suzuki, Y.; Kamisaka, S.; Masuda, Y.
Indole-3-acetyldehyde oxidase of pea seedlings
Physiol. Plant.
51
402-406
1981
Pisum sativum
-
brenda
Rajagopal, R.
Metabolism of indole-3-acetaldehyde. III. Some characteristics of the aldehyde oxidase of Avena coleoptiles
Physiol. Plant.
24
272-281
1971
Avena sativa
-
brenda
Koshiba, T.; Matsuyama, H.
An in vitro system of indole-3-acetic acid formation from tryptophan in maize (Zea mays) coleoptile extracts
Plant Physiol.
102
1319-1324
1993
Zea mays
brenda
Seo, M.; Akaba, S.; Oritani, T.; Delarue, M.; Bellini, C.; Caboche, M.; Koshiba, T.
Higher activity of an aldehyde oxidase in the auxin-overproducing superroot1 mutant of Arabidopsis thaliana
Plant Physiol.
116
687-693
1998
Arabidopsis thaliana
brenda
Zarepour, M.; Simon, K.; Wilch, M.; Nielaender, U.; Koshiba, T.; Seo, M.; Lindel, T.; Bittner, F.
Identification of superoxide production by Arabidopsis thaliana aldehyde oxidases AAO1 and AAO3
Plant Mol. Biol.
80
659-671
2012
Arabidopsis thaliana (Q7G193)
brenda
Select items on the left to see more content.
html completed