Disease on EC 1.5.3.16 - spermine oxidase
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Adenocarcinoma
Induction of the PAOh1/SMO polyamine oxidase by polyamine analogues in human lung carcinoma cells.
Brain Infarction
Aggravation of brain infarction through an increase in acrolein production and a decrease in glutathione with aging.
Brain Injuries
Astrocyte-Dependent Vulnerability to Excitotoxicity in Spermine Oxidase-Overexpressing Mouse.
Breast Neoplasms
Spermine oxidase (SMO) activity in breast tumor tissues and biochemical analysis of the anticancer spermine analogues BENSpm and CPENSpm.
Breast Neoplasms
Spermine oxidase SMO(PAOh1), Not N1-acetylpolyamine oxidase PAO, is the primary source of cytotoxic H2O2 in polyamine analogue-treated human breast cancer cell lines.
Carcinogenesis
Epigenetic silencing of miR-124 prevents spermine oxidase regulation: implications for Helicobacter pylori-induced gastric cancer.
Carcinogenesis
Increased spermine oxidase expression in human prostate cancer and prostatic intraepithelial neoplasia tissues.
Carcinogenesis
Nuclear localization of human spermine oxidase isoforms - possible implications in drug response and disease etiology.
Carcinogenesis
The Mechanism of Bacteroides fragilis Toxin Contributes to Colon Cancer Formation.
Carcinogenesis
Tumor necrosis factor-alpha increases reactive oxygen species by inducing spermine oxidase in human lung epithelial cells: a potential mechanism for inflammation-induced carcinogenesis.
Carcinoma
Induction of the PAOh1/SMO polyamine oxidase by polyamine analogues in human lung carcinoma cells.
Carcinoma, Hepatocellular
Spermine oxidase is upregulated and promotes tumor growth in hepatocellular carcinoma.
Colitis
Distinct Immunomodulatory Effects of Spermine Oxidase in Colitis Induced by Epithelial Injury or Infection.
Colitis, Ulcerative
Increased expression and cellular localization of spermine oxidase in ulcerative colitis and relationship to disease activity.
Colorectal Neoplasms
Polyamine catabolism in colorectal cancer cells following treatment with oxaliplatin, 5-fluorouracil and N1, N11 diethylnorspermine.
Colorectal Neoplasms
The roles of microbial products in the development of colorectal cancer: a review.
Diabetic Retinopathy
Spermine oxidase: A promising therapeutic target for neurodegeneration in diabetic retinopathy.
Epilepsy
Epileptic seizures and oxidative stress in a mouse model over-expressing spermine oxidase.
Gastritis
Epigenetic silencing of miR-124 prevents spermine oxidase regulation: implications for Helicobacter pylori-induced gastric cancer.
Gastritis
Spermine oxidation induced by Helicobacter pylori results in apoptosis and DNA damage: implications for gastric carcinogenesis.
Herpes Zoster
Identification of reproduction-related genes and SSR-markers through expressed sequence tags analysis of a monsoon breeding carp rohu, Labeo rohita (Hamilton).
Hypersensitivity
Chronic sub-lethal oxidative stress by spermine oxidase overactivity induces continuous DNA repair and hypersensitivity to radiation exposure.
Infections
Cotton polyamine oxidase is required for spermine and camalexin signalling in the defence response to Verticillium dahliae.
Infections
Distinct Immunomodulatory Effects of Spermine Oxidase in Colitis Induced by Epithelial Injury or Infection.
Infections
Increased Helicobacter pylori-associated gastric cancer risk in the Andean region of Colombia is mediated by spermine oxidase.
Infections
Spermine oxidation induced by Helicobacter pylori results in apoptosis and DNA damage: implications for gastric carcinogenesis.
Inflammatory Bowel Diseases
The roles of microbial products in the development of colorectal cancer: a review.
Kidney Failure, Chronic
Polyamine oxidase and acrolein as novel biochemical markers for diagnosis of cerebral stroke.
Lung Neoplasms
Induction of the PAOh1/SMO polyamine oxidase by polyamine analogues in human lung carcinoma cells.
Muscular Atrophy
Spermine oxidase maintains basal skeletal muscle gene expression and fiber size and is strongly repressed by conditions that cause skeletal muscle atrophy.
Neoplasms
Genetic regulation of spermine oxidase activity and cancer risk: a Mendelian randomization study.
Neoplasms
Increased spermine oxidase expression in human prostate cancer and prostatic intraepithelial neoplasia tissues.
Neoplasms
Induction of the PAOh1/SMO polyamine oxidase by polyamine analogues in human lung carcinoma cells.
Neoplasms
Purvalanol A is a strong apoptotic inducer via activating polyamine catabolic pathway in MCF-7 estrogen receptor positive breast cancer cells.
Neoplasms
Spermine metabolism and radiation-derived reactive oxygen species for future therapeutic implications in cancer: an additive or adaptive response.
Neoplasms
Spermine oxidase is upregulated and promotes tumor growth in hepatocellular carcinoma.
Neoplasms
The polyamine analog PG11047 potentiates the antitumor activity of cisplatin and bevacizumab in preclinical models of lung and prostate cancer.
Neoplasms
The roles of microbial products in the development of colorectal cancer: a review.
Neoplasms
Tumor necrosis factor-alpha increases reactive oxygen species by inducing spermine oxidase in human lung epithelial cells: a potential mechanism for inflammation-induced carcinogenesis.
Neuroblastoma
Chronic sub-lethal oxidative stress by spermine oxidase overactivity induces continuous DNA repair and hypersensitivity to radiation exposure.
Neuroblastoma
Direct oxidative DNA damage, apoptosis and radio sensitivity by spermine oxidase activities in mouse neuroblastoma cells.
Neuroblastoma
HIV-Tat Induces the Nrf2/ARE Pathway through NMDA Receptor-Elicited Spermine Oxidase Activation in Human Neuroblastoma Cells.
Neuroblastoma
Link between spermine oxidase and apoptosis antagonizing transcription factor: A new pathway in neuroblastoma.
Neuroblastoma
Mouse spermine oxidase gene splice variants. Nuclear subcellular localization of a novel active isoform.
Ovarian Neoplasms
Polyamine catabolism in platinum drug action: Interactions between oxaliplatin and the polyamine analogue N1,N11-diethylnorspermine at the level of spermidine/spermine N1-acetyltransferase.
Pancreatitis
[Methylated analogues of spermine and spermidine as tools to investigate cellular functions of polyamines and the enzymes of their metabolism]
Prostatic Intraepithelial Neoplasia
Increased spermine oxidase expression in human prostate cancer and prostatic intraepithelial neoplasia tissues.
Prostatic Neoplasms
Increased spermine oxidase expression in human prostate cancer and prostatic intraepithelial neoplasia tissues.
Prostatic Neoplasms
Polyamine Analogues of Propanediamine Series Inhibit Prostate Tumor Cell Growth and Activate the Polyamine Catabolic Pathway.
Reperfusion Injury
The Role of Spermidine/Spermine-N1-Acetyltransferase in Endotoxin-Induced Acute Kidney Injury.
Seizures
Astrocyte-Dependent Vulnerability to Excitotoxicity in Spermine Oxidase-Overexpressing Mouse.
Seizures
Epileptic seizures and oxidative stress in a mouse model over-expressing spermine oxidase.
Stomach Diseases
Human and Helicobacter pylori Interactions Determine the Outcome of Gastric Diseases.
Stomach Neoplasms
Epigenetic silencing of miR-124 prevents spermine oxidase regulation: implications for Helicobacter pylori-induced gastric cancer.
Stomach Neoplasms
Increased Helicobacter pylori-associated gastric cancer risk in the Andean region of Colombia is mediated by spermine oxidase.
Stomach Neoplasms
Spermine oxidase mediates Helicobacter pylori-induced gastric inflammation, DNA damage, and carcinogenic signaling.
Stomach Neoplasms
Spermine Oxidase Mediates the Gastric Cancer Risk Associated With Helicobacter pylori CagA.
Stomach Neoplasms
Spermine oxidase, a polyamine catabolic enzyme that links Helicobacter pylori CagA and gastric cancer risk.
Stomach Neoplasms
Spermine oxidation induced by Helicobacter pylori results in apoptosis and DNA damage: implications for gastric carcinogenesis.
Zika Virus Infection
Polymeric Prodrugs Targeting Polyamine Metabolism Inhibit Zika Virus Replication.
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